Compile Data Set for Download or QSAR
Found 27 Enz. Inhib. hit(s) with all data for entry = 50032970
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50337121(2-chloro-4-(((6-cyanobiphenyl-3-yl)(4H-1,2,4-triaz...)copy SMILEScopy InChI
Affinity DataIC50: 0.0150nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X067BNPubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50337123(4-(((6-cyano-4'-methoxybiphenyl-3-yl)(4H-1,2,4-tri...)copy SMILEScopy InChI
Affinity DataIC50: 0.0150nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X067BNPubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50337122(2-bromo-4-(((6-cyanobiphenyl-3-yl)(4H-1,2,4-triazo...)copy SMILEScopy InChI
Affinity DataIC50: 0.0180nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X067BNPubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50337118(5'-((4-bromobenzyl)(4H-1,2,4-triazol-4-yl)amino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X067BNPubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50337117(5'-(benzyl(4H-1,2,4-triazol-4-yl)amino)-2'-cyanobi...)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X067BNPubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50337122(2-bromo-4-(((6-cyanobiphenyl-3-yl)(4H-1,2,4-triazo...)copy SMILEScopy InChI
Affinity DataIC50: 0.130nMAssay Description:Inhibition of steroid sulfatase in human JEG-3 cells using [6,7-3H]E1S after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X067BNPubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50337120(4-(((6-cyanobiphenyl-3-yl)(4H-1,2,4-triazol-4-yl)a...)copy SMILEScopy InChI
Affinity DataIC50: 0.150nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X067BNPubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50337119(4-(((6-cyanobiphenyl-3-yl)(4H-1,2,4-triazol-4-yl)a...)copy SMILEScopy InChI
Affinity DataIC50: 0.210nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X067BNPubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50337124(4-(((6-cyano-4'-fluorobiphenyl-3-yl)(4H-1,2,4-tria...)copy SMILEScopy InChI
Affinity DataIC50: 0.470nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X067BNPubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM10016(4-{[(4-bromophenyl)methyl](4H-1,2,4-triazol-4-yl)a...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X067BNPubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50307884(3-CHLORO-2'-CYANO-5'-(1H-1,2,4-TRIAZOL-1-YLMETHYL)...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X067BNPubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50337125(4-(((4',6-dicyanobiphenyl-3-yl)(4H-1,2,4-triazol-4...)copy SMILEScopy InChI
Affinity DataIC50: 0.75nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X067BNPubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM10020((2-bromo-4-{[(4-cyanophenyl)(4H-1,2,4-triazol-4-yl...)copy SMILEScopy InChI
Affinity DataIC50: 0.820nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X067BNPubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50337121(2-chloro-4-(((6-cyanobiphenyl-3-yl)(4H-1,2,4-triaz...)copy SMILEScopy InChI
Affinity DataIC50: 0.830nMAssay Description:Inhibition of steroid sulfatase in human JEG-3 cells using [6,7-3H]E1S after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X067BNPubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50307886(5'-((1H-1,2,4-triazol-1-yl)methyl)-2'-cyanobipheny...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X067BNPubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50337120(4-(((6-cyanobiphenyl-3-yl)(4H-1,2,4-triazol-4-yl)a...)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:Inhibition of steroid sulfatase in human JEG-3 cells using [6,7-3H]E1S after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X067BNPubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50307884(3-CHLORO-2'-CYANO-5'-(1H-1,2,4-TRIAZOL-1-YLMETHYL)...)copy SMILEScopy InChI
Affinity DataIC50: 5.5nMAssay Description:Inhibition of steroid sulfatase in human JEG-3 cells using [6,7-3H]E1S after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X067BNPubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50337119(4-(((6-cyanobiphenyl-3-yl)(4H-1,2,4-triazol-4-yl)a...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of steroid sulfatase in human JEG-3 cells using [6,7-3H]E1S after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X067BNPubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50337123(4-(((6-cyano-4'-methoxybiphenyl-3-yl)(4H-1,2,4-tri...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of steroid sulfatase in human JEG-3 cells using [6,7-3H]E1S after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X067BNPubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50307886(5'-((1H-1,2,4-triazol-1-yl)methyl)-2'-cyanobipheny...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of steroid sulfatase in human JEG-3 cells using [6,7-3H]E1S after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X067BNPubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM10020((2-bromo-4-{[(4-cyanophenyl)(4H-1,2,4-triazol-4-yl...)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Inhibition of steroid sulfatase in human JEG-3 cells using [6,7-3H]E1S after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X067BNPubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50337124(4-(((6-cyano-4'-fluorobiphenyl-3-yl)(4H-1,2,4-tria...)copy SMILEScopy InChI
Affinity DataIC50: 55nMAssay Description:Inhibition of steroid sulfatase in human JEG-3 cells using [6,7-3H]E1S after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X067BNPubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM10017((4-{[(4-cyanophenyl)(4H-1,2,4-triazol-4-yl)amino]m...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X067BNPubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50337125(4-(((4',6-dicyanobiphenyl-3-yl)(4H-1,2,4-triazol-4...)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Inhibition of steroid sulfatase in human JEG-3 cells using [6,7-3H]E1S after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X067BNPubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM10017((4-{[(4-cyanophenyl)(4H-1,2,4-triazol-4-yl)amino]m...)copy SMILEScopy InChI
Affinity DataIC50: 277nMAssay Description:Inhibition of steroid sulfatase in human JEG-3 cells using [6,7-3H]E1S after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X067BNPubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50337117(5'-(benzyl(4H-1,2,4-triazol-4-yl)amino)-2'-cyanobi...)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of steroid sulfatase in human JEG-3 cells using [6,7-3H]E1S after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X067BNPubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50337118(5'-((4-bromobenzyl)(4H-1,2,4-triazol-4-yl)amino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of steroid sulfatase in human JEG-3 cells using [6,7-3H]E1S after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X067BNPubMed