Compile Data Set for Download or QSAR
Found 33 Enz. Inhib. hit(s) with all data for entry = 50032974
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50337199(4-((S)-3-((S)-1-(6-(Benzylcarbamoyl)-4'-carbamoylb...)copy SMILEScopy InChI
Affinity DataKi:  5.00E+3nMAssay Description:Displacement of 5-carboxyfluorescein-GpYLPQTV-NH2 from mouse recombinant His-tagged STAT3-SH2 domain expressed in Escherichia coli BL21 (DE3) by fluo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ4058PubMed
TargetSignal transducer and activator of transcription 1(Mus musculus)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50337199(4-((S)-3-((S)-1-(6-(Benzylcarbamoyl)-4'-carbamoylb...)copy SMILEScopy InChI
Affinity DataKi:  6.30E+3nMAssay Description:Displacement of 5-carboxyfluorescein-GpYDKPHVL-NH2 from mouse recombinant His-tagged STAT1-SH2 domain expressed in Escherichia coli BL21 (DE3) by flu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ4058PubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50337198((S)-3-(((S)-1-((5-(Benzylcarbamoyl)-4'-carbamoyl-[...)copy SMILEScopy InChI
Affinity DataKi:  9.00E+3nMAssay Description:Displacement of 5-carboxyfluorescein-GpYLPQTV-NH2 from mouse recombinant His-tagged STAT3-SH2 domain expressed in Escherichia coli BL21 (DE3) by fluo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ4058PubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50337205(CHEMBL1684879 | Methyl 2'-(benzylcarbamoyl)-5'-((S...)copy SMILEScopy InChI
Affinity DataKi:  1.00E+4nMAssay Description:Displacement of 5-carboxyfluorescein-GpYLPQTV-NH2 from mouse recombinant His-tagged STAT3-SH2 domain expressed in Escherichia coli BL21 (DE3) by fluo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ4058PubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50337209(4-((S)-3-(((S)-1-((6-(Benzylcarbamoyl)-4'-cyano-[1...)copy SMILEScopy InChI
Affinity DataKi:  1.10E+4nMAssay Description:Displacement of 5-carboxyfluorescein-GpYLPQTV-NH2 from mouse recombinant His-tagged STAT3-SH2 domain expressed in Escherichia coli BL21 (DE3) by fluo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ4058PubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50337206(4-((S)-3-(((S)-1-((6-(Benzylcarbamoyl)-3'-cyano-[1...)copy SMILEScopy InChI
Affinity DataKi:  1.30E+4nMAssay Description:Displacement of 5-carboxyfluorescein-GpYLPQTV-NH2 from mouse recombinant His-tagged STAT3-SH2 domain expressed in Escherichia coli BL21 (DE3) by fluo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ4058PubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50337207(4-((S)-3-(((S)-1-((6-(Benzylcarbamoyl)-3'-carbamoy...)copy SMILEScopy InChI
Affinity DataKi:  1.50E+4nMAssay Description:Displacement of 5-carboxyfluorescein-GpYLPQTV-NH2 from mouse recombinant His-tagged STAT3-SH2 domain expressed in Escherichia coli BL21 (DE3) by fluo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ4058PubMed
TargetSignal transducer and activator of transcription 1(Mus musculus)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50337198((S)-3-(((S)-1-((5-(Benzylcarbamoyl)-4'-carbamoyl-[...)copy SMILEScopy InChI
Affinity DataKi:  1.65E+4nMAssay Description:Displacement of 5-carboxyfluorescein-GpYDKPHVL-NH2 from mouse recombinant His-tagged STAT1-SH2 domain expressed in Escherichia coli BL21 (DE3) by flu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ4058PubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50337201(4-((S)-3-(((S)-1-((5-(Benzylcarbamoyl)-3'-cyano-[1...)copy SMILEScopy InChI
Affinity DataKi:  1.80E+4nMAssay Description:Displacement of 5-carboxyfluorescein-GpYLPQTV-NH2 from mouse recombinant His-tagged STAT3-SH2 domain expressed in Escherichia coli BL21 (DE3) by fluo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ4058PubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50337200(CHEMBL1681829 | Methyl 3'-(benzylcarbamoyl)-5'-((S...)copy SMILEScopy InChI
Affinity DataKi:  2.30E+4nMAssay Description:Displacement of 5-carboxyfluorescein-GpYLPQTV-NH2 from mouse recombinant His-tagged STAT3-SH2 domain expressed in Escherichia coli BL21 (DE3) by fluo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ4058PubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50337203(CHEMBL1681826 | Methyl 3'-(benzylcarbamoyl)-5'-((S...)copy SMILEScopy InChI
Affinity DataKi:  2.50E+4nMAssay Description:Displacement of 5-carboxyfluorescein-GpYLPQTV-NH2 from mouse recombinant His-tagged STAT3-SH2 domain expressed in Escherichia coli BL21 (DE3) by fluo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ4058PubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50337208(CHEMBL1684874 | Methyl 2'-(benzylcarbamoyl)-5'-((S...)copy SMILEScopy InChI
Affinity DataKi:  2.60E+4nMAssay Description:Displacement of 5-carboxyfluorescein-GpYLPQTV-NH2 from mouse recombinant His-tagged STAT3-SH2 domain expressed in Escherichia coli BL21 (DE3) by fluo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ4058PubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50337204(4-((S)-3-(((S)-1-((5-(Benzylcarbamoyl)-4'-cyano-[1...)copy SMILEScopy InChI
Affinity DataKi:  3.60E+4nMAssay Description:Displacement of 5-carboxyfluorescein-GpYLPQTV-NH2 from mouse recombinant His-tagged STAT3-SH2 domain expressed in Escherichia coli BL21 (DE3) by fluo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ4058PubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50337202(4-((S)-3-(((S)-1-((5-(Benzylcarbamoyl)-3'-carbamoy...)copy SMILEScopy InChI
Affinity DataKi:  3.80E+4nMAssay Description:Displacement of 5-carboxyfluorescein-GpYLPQTV-NH2 from mouse recombinant His-tagged STAT3-SH2 domain expressed in Escherichia coli BL21 (DE3) by fluo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ4058PubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50337198((S)-3-(((S)-1-((5-(Benzylcarbamoyl)-4'-carbamoyl-[...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of STAT3 dimerization in mouse NIH3T3 cells expressing v-Src assessed as disruption of STAT3-STAT3: DNA complexation in nucleus after 30 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ4058PubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50337209(4-((S)-3-(((S)-1-((6-(Benzylcarbamoyl)-4'-cyano-[1...)copy SMILEScopy InChI
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of STAT3 dimerization in mouse NIH3T3 cells expressing v-Src assessed as disruption of STAT3-STAT3: DNA complexation in nucleus after 30 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ4058PubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50337205(CHEMBL1684879 | Methyl 2'-(benzylcarbamoyl)-5'-((S...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of STAT3 dimerization in mouse NIH3T3 cells expressing v-Src assessed as disruption of STAT3-STAT3: DNA complexation in nucleus after 30 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ4058PubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50337204(4-((S)-3-(((S)-1-((5-(Benzylcarbamoyl)-4'-cyano-[1...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of STAT3 dimerization in mouse NIH3T3 cells expressing v-Src assessed as disruption of STAT3-STAT3: DNA complexation in nucleus after 30 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ4058PubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50337207(4-((S)-3-(((S)-1-((6-(Benzylcarbamoyl)-3'-carbamoy...)copy SMILEScopy InChI
Affinity DataIC50: 6.20E+4nMAssay Description:Inhibition of STAT3 dimerization in mouse NIH3T3 cells expressing v-Src assessed as disruption of STAT3-STAT3: DNA complexation in nucleus after 30 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ4058PubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50337206(4-((S)-3-(((S)-1-((6-(Benzylcarbamoyl)-3'-cyano-[1...)copy SMILEScopy InChI
Affinity DataIC50: 6.40E+4nMAssay Description:Inhibition of STAT3 dimerization in mouse NIH3T3 cells expressing v-Src assessed as disruption of STAT3-STAT3: DNA complexation in nucleus after 30 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ4058PubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50337200(CHEMBL1681829 | Methyl 3'-(benzylcarbamoyl)-5'-((S...)copy SMILEScopy InChI
Affinity DataIC50: 6.60E+4nMAssay Description:Inhibition of STAT3 dimerization in mouse NIH3T3 cells expressing v-Src assessed as disruption of STAT3-STAT3: DNA complexation in nucleus after 30 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ4058PubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50337199(4-((S)-3-((S)-1-(6-(Benzylcarbamoyl)-4'-carbamoylb...)copy SMILEScopy InChI
Affinity DataIC50: 7.31E+4nMAssay Description:Inhibition of STAT3 dimerization in mouse NIH3T3 cells expressing v-Src assessed as disruption of STAT3-STAT3: DNA complexation in nucleus after 30 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ4058PubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50337201(4-((S)-3-(((S)-1-((5-(Benzylcarbamoyl)-3'-cyano-[1...)copy SMILEScopy InChI
Affinity DataIC50: 9.20E+4nMAssay Description:Inhibition of STAT3 dimerization in mouse NIH3T3 cells expressing v-Src assessed as disruption of STAT3-STAT3: DNA complexation in nucleus after 30 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ4058PubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50337196(CHEMBL1684875 | N2-benzyl-5-((S)-2-((S)-2-(4-cyano...)copy SMILEScopy InChI
Affinity DataIC50: 1.03E+5nMAssay Description:Inhibition of STAT3 dimerization in mouse NIH3T3 cells expressing v-Src assessed as disruption of STAT3-STAT3: DNA complexation in nucleus after 30 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ4058PubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50337203(CHEMBL1681826 | Methyl 3'-(benzylcarbamoyl)-5'-((S...)copy SMILEScopy InChI
Affinity DataIC50: 1.12E+5nMAssay Description:Inhibition of STAT3 dimerization in mouse NIH3T3 cells expressing v-Src assessed as disruption of STAT3-STAT3: DNA complexation in nucleus after 30 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ4058PubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50337202(4-((S)-3-(((S)-1-((5-(Benzylcarbamoyl)-3'-carbamoy...)copy SMILEScopy InChI
Affinity DataIC50: 1.88E+5nMAssay Description:Inhibition of STAT3 dimerization in mouse NIH3T3 cells expressing v-Src assessed as disruption of STAT3-STAT3: DNA complexation in nucleus after 30 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ4058PubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50337197(CHEMBL1684876 | N3-benzyl-5-((S)-2-((S)-2-(4-cyano...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+5nMAssay Description:Inhibition of STAT3 dimerization in mouse NIH3T3 cells expressing v-Src assessed as disruption of STAT3-STAT3: DNA complexation in nucleus after 30 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ4058PubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50337208(CHEMBL1684874 | Methyl 2'-(benzylcarbamoyl)-5'-((S...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of STAT3 dimerization in mouse NIH3T3 cells expressing v-Src assessed as disruption of STAT3-STAT3: DNA complexation in nucleus after 30 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ4058PubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50337196(CHEMBL1684875 | N2-benzyl-5-((S)-2-((S)-2-(4-cyano...)copy SMILEScopy InChI
Affinity DataKd:  12nMAssay Description:Inhibition of mouse recombinant SH2 domain of His-tagged full-length STAT3 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ4058PubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50337197(CHEMBL1684876 | N3-benzyl-5-((S)-2-((S)-2-(4-cyano...)copy SMILEScopy InChI
Affinity DataKd:  17nMAssay Description:Inhibition of mouse recombinant SH2 domain of His-tagged full-length STAT3 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ4058PubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50337198((S)-3-(((S)-1-((5-(Benzylcarbamoyl)-4'-carbamoyl-[...)copy SMILEScopy InChI
Affinity DataKd:  205nMAssay Description:Inhibition of mouse recombinant SH2 domain of His-tagged full-length STAT3 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ4058PubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50337199(4-((S)-3-((S)-1-(6-(Benzylcarbamoyl)-4'-carbamoylb...)copy SMILEScopy InChI
Affinity DataKd:  900nMAssay Description:Inhibition of mouse recombinant SH2 domain of His-tagged full-length STAT3 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ4058PubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50337195(CHEMBL1684871 | GpYLPQTV-NH2)copy SMILEScopy InChI
Affinity DataKd:  24nMAssay Description:Inhibition of mouse recombinant SH2 domain of His-tagged full-length STAT3 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ4058PubMed