Compile Data Set for Download or QSAR
Found 77 Enz. Inhib. hit(s) with all data for entry = 50033205
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50341350(2-(1-Acetyl-piperidin-4-ylamino)-6-(2,4-difluoroph...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant p38alpha assessed as incorporation of 33P from gamma-[33P]ATP into myelin basic protein after 30 mins by scintillatio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P109XPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50341370(6-(2,4-Difluorophenoxy)-8-(1-methanesulfonyl-piper...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant p38alpha assessed as incorporation of 33P from gamma-[33P]ATP into myelin basic protein after 30 mins by scintillatio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P109XPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50341361(6-(2,4-Difluorophenoxy)-8-ethyl-2-(tetrahydro-2H-p...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant p38alpha assessed as incorporation of 33P from gamma-[33P]ATP into myelin basic protein after 30 mins by scintillatio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P109XPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50341366(6-(2,4-Difluorophenoxy)-8-(1,1-dioxo-hexahydro-thi...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant p38alpha assessed as incorporation of 33P from gamma-[33P]ATP into myelin basic protein after 30 mins by scintillatio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P109XPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50341363(6-(2,4-Difluorophenoxy)-8-(3-hydroxy-propyl)-2-(te...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant p38alpha assessed as incorporation of 33P from gamma-[33P]ATP into myelin basic protein after 30 mins by scintillatio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P109XPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50341356(6-(2,4-Difluorophenoxy)-8-methyl-2-((S)-1-methyl-2...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant p38alpha assessed as incorporation of 33P from gamma-[33P]ATP into myelin basic protein after 30 mins by scintillatio...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50341369(CHEMBL1766506 | [6-(2,4-Difluorophenoxy)-7-oxo-2-(...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant p38alpha assessed as incorporation of 33P from gamma-[33P]ATP into myelin basic protein after 30 mins by scintillatio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P109XPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50341352(CHEMBL1766580 | trans-6-(2,4-Difluorophenoxy)-2-(t...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant p38alpha assessed as incorporation of 33P from gamma-[33P]ATP into myelin basic protein after 30 mins by scintillatio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P109XPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50341372(6-(2,4-Difluorophenoxy)-2-isopropylamino-8-methyl-...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant p38alpha assessed as incorporation of 33P from gamma-[33P]ATP into myelin basic protein after 30 mins by scintillatio...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50341346((R)-6-(2,4-difluorophenoxy)-8-methyl-2-(1-(methyls...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant p38alpha assessed as incorporation of 33P from gamma-[33P]ATP into myelin basic protein after 30 mins by scintillatio...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50341365(6-(2,4-Difluorophenoxy)-8-(3-methanesulfonyl-propy...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant p38alpha assessed as incorporation of 33P from gamma-[33P]ATP into myelin basic protein after 30 mins by scintillatio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P109XPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50341368(6-(2,4-Difluorophenoxy)-8-((S)-2,3-dihydroxy-propy...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of human recombinant p38alpha assessed as incorporation of 33P from gamma-[33P]ATP into myelin basic protein after 30 mins by scintillatio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P109XPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50341362(6-(2,4-Difluorophenoxy)-8-cyclopropyl-2-(tetrahydr...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant p38alpha assessed as incorporation of 33P from gamma-[33P]ATP into myelin basic protein after 30 mins by scintillatio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P109XPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50341342(6-(2,4-difluorophenoxy)-8-methyl-2-(tetrahydro-2H-...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant p38alpha assessed as incorporation of 33P from gamma-[33P]ATP into myelin basic protein after 30 mins by scintillatio...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50341358(6-(2,4-Difluoro-phenoxy)-8-methyl-2-((R)-1-methyl-...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant p38alpha assessed as incorporation of 33P from gamma-[33P]ATP into myelin basic protein after 30 mins by scintillatio...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50341367(6-(2,4-Difluorophenoxy)-8-(2-hydroxy-2-methyl-prop...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant p38alpha assessed as incorporation of 33P from gamma-[33P]ATP into myelin basic protein after 30 mins by scintillatio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P109XPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50341349(6-(4-Fluorophenoxy)-8-methyl-2-(tetrahydro-2H-pyra...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant p38alpha assessed as incorporation of 33P from gamma-[33P]ATP into myelin basic protein after 30 mins by scintillatio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P109XPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50314070(6-(2,4-difluorophenoxy)-2-{[3-hydroxy-1-(2-hydroxy...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant p38alpha assessed as incorporation of 33P from gamma-[33P]ATP into myelin basic protein after 30 mins by scintillatio...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50341353(6-(2-Fluorophenoxy)-8-methyl-2-(tetrahydro-2H-pyra...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant p38alpha assessed as incorporation of 33P from gamma-[33P]ATP into myelin basic protein after 30 mins by scintillatio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P109XPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50341354(2-[(1,1-Dioxidotetrahydro-2H-thiopyran-4-yl)amino]...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant p38alpha assessed as incorporation of 33P from gamma-[33P]ATP into myelin basic protein after 30 mins by scintillatio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P109XPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50341360(6-(2,4-Difluorophenoxy)-8H-2-(tetrahydro-2H-pyran-...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of human recombinant p38alpha assessed as incorporation of 33P from gamma-[33P]ATP into myelin basic protein after 30 mins by scintillatio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P109XPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50341364(6-(2,4-Difluorophenoxy)-8-(2-methanesulfonyl-ethyl...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant p38alpha assessed as incorporation of 33P from gamma-[33P]ATP into myelin basic protein after 30 mins by scintillatio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P109XPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50341345(6-(2-Chlorophenyl)-8-methyl-2-(tetrahydro-2H-pyran...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of human recombinant p38alpha assessed as incorporation of 33P from gamma-[33P]ATP into myelin basic protein after 30 mins by scintillatio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P109XPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50341375(6-(2,4-Difluorophenoxy)-2-(2-hydroxy-1,1-dimethyl-...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of human recombinant p38alpha assessed as incorporation of 33P from gamma-[33P]ATP into myelin basic protein after 30 mins by scintillatio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P109XPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50341373(6-(2,4-Difluorophenoxy)-8-methyl-2-[(S)-(tetrahydr...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of human recombinant p38alpha assessed as incorporation of 33P from gamma-[33P]ATP into myelin basic protein after 30 mins by scintillatio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P109XPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50341359(6-(2,4-Difluorobenzyl)-8-methyl-2-(tetrahydro-2H-p...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant p38alpha assessed as incorporation of 33P from gamma-[33P]ATP into myelin basic protein after 30 mins by scintillatio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P109XPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50341357(6-(2-Fluorobenzyl)-8-methyl-2-(tetrahydro-2H-pyran...)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Inhibition of human recombinant p38alpha assessed as incorporation of 33P from gamma-[33P]ATP into myelin basic protein after 30 mins by scintillatio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P109XPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50341348(6-(2,4-Difluorophenoxy)-2-((S)-2-methanesulfonyl-1...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of human recombinant p38alpha assessed as incorporation of 33P from gamma-[33P]ATP into myelin basic protein after 30 mins by scintillatio...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50341374(6-(2,4-Difluorophenoxy)-2-(2-hydroxy-2-methyl-prop...)copy SMILEScopy InChI
Affinity DataIC50: 67nMAssay Description:Inhibition of human recombinant p38alpha assessed as incorporation of 33P from gamma-[33P]ATP into myelin basic protein after 30 mins by scintillatio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P109XPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50341347(6-(Phenoxy)-8-methyl-2-(tetrahydro-2H-pyran-4-ylam...)copy SMILEScopy InChI
Affinity DataIC50: 106nMAssay Description:Inhibition of human recombinant p38alpha assessed as incorporation of 33P from gamma-[33P]ATP into myelin basic protein after 30 mins by scintillatio...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50341355(6-(2-Fluorophenylthio)-8-methyl-2-(tetrahydro-2H-p...)copy SMILEScopy InChI
Affinity DataIC50: 111nMAssay Description:Inhibition of human recombinant p38alpha assessed as incorporation of 33P from gamma-[33P]ATP into myelin basic protein after 30 mins by scintillatio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P109XPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50341343(6-(2,4-Difluorophenoxy)-2-(2-hydroxy-1-hydroxymeth...)copy SMILEScopy InChI
Affinity DataIC50: 158nMAssay Description:Inhibition of human recombinant p38alpha assessed as incorporation of 33P from gamma-[33P]ATP into myelin basic protein after 30 mins by scintillatio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P109XPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50341344(2-(2'-Methylsulfonylethylamino))-6-(2,4-difluoroph...)copy SMILEScopy InChI
Affinity DataIC50: 223nMAssay Description:Inhibition of human recombinant p38alpha assessed as incorporation of 33P from gamma-[33P]ATP into myelin basic protein after 30 mins by scintillatio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P109XPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50341371(6-(2,4-Difluorophenoxy)-8-methyl-2-methylamino-8H-...)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:Inhibition of human recombinant p38alpha assessed as incorporation of 33P from gamma-[33P]ATP into myelin basic protein after 30 mins by scintillatio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P109XPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50341351(6-(3-Fluorophenoxy)-8-methyl-2-(tetrahydro-2H-pyra...)copy SMILEScopy InChI
Affinity DataIC50: 594nMAssay Description:Inhibition of human recombinant p38alpha assessed as incorporation of 33P from gamma-[33P]ATP into myelin basic protein after 30 mins by scintillatio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P109XPubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50314070(6-(2,4-difluorophenoxy)-2-{[3-hydroxy-1-(2-hydroxy...)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P109XPubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50314070(6-(2,4-difluorophenoxy)-2-{[3-hydroxy-1-(2-hydroxy...)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P109XPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50314070(6-(2,4-difluorophenoxy)-2-{[3-hydroxy-1-(2-hydroxy...)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P109XPubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50314070(6-(2,4-difluorophenoxy)-2-{[3-hydroxy-1-(2-hydroxy...)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P109XPubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50314070(6-(2,4-difluorophenoxy)-2-{[3-hydroxy-1-(2-hydroxy...)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P109XPubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50341342(6-(2,4-difluorophenoxy)-8-methyl-2-(tetrahydro-2H-...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P109XPubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50341342(6-(2,4-difluorophenoxy)-8-methyl-2-(tetrahydro-2H-...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P109XPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50341342(6-(2,4-difluorophenoxy)-8-methyl-2-(tetrahydro-2H-...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P109XPubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50341342(6-(2,4-difluorophenoxy)-8-methyl-2-(tetrahydro-2H-...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P109XPubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50341342(6-(2,4-difluorophenoxy)-8-methyl-2-(tetrahydro-2H-...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P109XPubMed
TargetMitogen-activated protein kinase 11(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50314070(6-(2,4-difluorophenoxy)-2-{[3-hydroxy-1-(2-hydroxy...)copy SMILEScopy InChI
Affinity DataKd:  120nMAssay Description:Inhibition of P38betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P109XPubMed
TargetAtypical kinase COQ8A, mitochondrial(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50314070(6-(2,4-difluorophenoxy)-2-{[3-hydroxy-1-(2-hydroxy...)copy SMILEScopy InChI
Affinity DataKd: >1.00E+3nMAssay Description:Inhibition of ADCK3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P109XPubMed
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50314070(6-(2,4-difluorophenoxy)-2-{[3-hydroxy-1-(2-hydroxy...)copy SMILEScopy InChI
Affinity DataKd:  260nMAssay Description:Inhibition of CSNK1epsilonMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P109XPubMed
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50314070(6-(2,4-difluorophenoxy)-2-{[3-hydroxy-1-(2-hydroxy...)copy SMILEScopy InChI
Affinity DataKd: >1.00E+3nMAssay Description:Inhibition of DDR1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P109XPubMed
TargetCyclin-G-associated kinase(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50314070(6-(2,4-difluorophenoxy)-2-{[3-hydroxy-1-(2-hydroxy...)copy SMILEScopy InChI
Affinity DataKd: >1.00E+3nMAssay Description:Inhibition of GAKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P109XPubMed
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