TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of human DGAT1More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:Inhibition of human DGAT1 using [14C]palmitic acid by TLC analysisMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 41nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected Sf9 cells using [14C]oleoyl-CoA after 15 mins by TLC analysisMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 48nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 57nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 59nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 67nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 68nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 71nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 77nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 82nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 84nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 84nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 113nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 128nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 128nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 136nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 165nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 202nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 237nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 277nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 325nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 1.51E+4nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 2.47E+4nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
Affinity DataIC50: 6.84E+4nMAssay Description:Inhibition of human ACAT1 expressed in human HepG2 cells after incubated with compound for 15 mins measured after 1 hr using palmitoyl-1-14C-coenzyme...More data for this Ligand-Target Pair
Affinity DataIC50: 6.84E+4nMAssay Description:Inhibition of human ACAT2 expressed in human HepG2 cells after incubated with compound for 15 mins measured after 1 hr using palmitoyl-1-14C-coenzyme...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human DGAT2 expressed in baculovirus infected Sf9 cells using palmitoyl-1-14C-coenzyme A by TLC assayMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataEC50: 1.44E+3nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataEC50: 2.36E+3nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataEC50: 1.07E+3nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataEC50: 1.76E+3nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataEC50: 371nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataEC50: 362nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataEC50: 165nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataEC50: 190nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataEC50: 378nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataEC50: 219nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataEC50: 410nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataEC50: 93nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataEC50: 138nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataEC50: 216nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair