Compile Data Set for Download or QSAR
Found 48 Enz. Inhib. hit(s) with all data for entry = 50033451
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50345579(5-((5-(4-((4-(2-hydroxyethyl)piperazin-1-yl)methyl...)copy SMILEScopy InChI
Affinity DataIC50: 0.150nMAssay Description:Inhibition of human LYN using poly[Glu:Tyr] by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0MM8PubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50345579(5-((5-(4-((4-(2-hydroxyethyl)piperazin-1-yl)methyl...)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibition of wild type human ABL using [EAIYAAPFAKKK] peptide substrate by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0MM8PubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50345579(5-((5-(4-((4-(2-hydroxyethyl)piperazin-1-yl)methyl...)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibition of wild type human ABL using [EAIYAAPFAKKK] peptide substrate by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0MM8PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50345579(5-((5-(4-((4-(2-hydroxyethyl)piperazin-1-yl)methyl...)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human RET using KKKSPGEYVNIEFG by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0MM8PubMed
TargetEphrin type-A receptor 2(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50345579(5-((5-(4-((4-(2-hydroxyethyl)piperazin-1-yl)methyl...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human EPHA2 using poly[Glu:Tyr] peptide substrate by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0MM8PubMed
TargetEphrin type-A receptor 3(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50345579(5-((5-(4-((4-(2-hydroxyethyl)piperazin-1-yl)methyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human EPHA3 using poly[Glu:Tyr] peptide substrate by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0MM8PubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50345579(5-((5-(4-((4-(2-hydroxyethyl)piperazin-1-yl)methyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human PDGFRalpha using poly[Glu:Tyr] by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0MM8PubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50345579(5-((5-(4-((4-(2-hydroxyethyl)piperazin-1-yl)methyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human FGFR2 using poly[Glu:Tyr] peptide substrate by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0MM8PubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50345579(5-((5-(4-((4-(2-hydroxyethyl)piperazin-1-yl)methyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human FGFR1 using KKKSPGEYVNIEFG peptide substrate by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0MM8PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50345579(5-((5-(4-((4-(2-hydroxyethyl)piperazin-1-yl)methyl...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of human FLT3 using EAIYAAPFAKKK peptide substrate by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0MM8PubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50345579(5-((5-(4-((4-(2-hydroxyethyl)piperazin-1-yl)methyl...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human Tie2/TEK using poly[Glu:Tyr] by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0MM8PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50345579(5-((5-(4-((4-(2-hydroxyethyl)piperazin-1-yl)methyl...)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human VEGFR2 using poly[Glu:Tyr] by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0MM8PubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50345579(5-((5-(4-((4-(2-hydroxyethyl)piperazin-1-yl)methyl...)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Inhibition of human VEGFR3 using poly[Glu:Tyr] by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0MM8PubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50345579(5-((5-(4-((4-(2-hydroxyethyl)piperazin-1-yl)methyl...)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Inhibition of human PDGFRbeta using poly[Glu:Tyr] by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0MM8PubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50345587(1-methyl-5-((2-methyl-5-(4-((4-methylpiperazin-1-y...)copy SMILEScopy InChI
Affinity DataIC50: 3.60nMAssay Description:Inhibition of wild type human ABL using [EAIYAAPFAKKK] peptide substrate by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0MM8PubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50345584(5-((5-(4-((4-(2-hydroxyethyl)piperazin-1-yl)methyl...)copy SMILEScopy InChI
Affinity DataIC50: 3.60nMAssay Description:Inhibition of wild type human ABL using [EAIYAAPFAKKK] peptide substrate by Hotspot assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50345579(5-((5-(4-((4-(2-hydroxyethyl)piperazin-1-yl)methyl...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human Src using poly[Glu:Tyr] by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0MM8PubMed
TargetEphrin type-A receptor 7(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50345579(5-((5-(4-((4-(2-hydroxyethyl)piperazin-1-yl)methyl...)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human EPHA7 using poly[Glu:Tyr] peptide substrate by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0MM8PubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50345582(2-(4-(4-(3-((2-carbamoyl-1-methyl-1H-imidazol-5-yl...)copy SMILEScopy InChI
Affinity DataIC50: 4.30nMAssay Description:Inhibition of wild type human ABL using [EAIYAAPFAKKK] peptide substrate by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0MM8PubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50345583(5-((5-(4-((4-(2-methoxyethyl)piperazin-1-yl)methyl...)copy SMILEScopy InChI
Affinity DataIC50: 4.80nMAssay Description:Inhibition of wild type human ABL using [EAIYAAPFAKKK] peptide substrate by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0MM8PubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50345579(5-((5-(4-((4-(2-hydroxyethyl)piperazin-1-yl)methyl...)copy SMILEScopy InChI
Affinity DataIC50: 5.20nMAssay Description:Inhibition of human VEGFR1 using poly[Glu:Tyr] by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0MM8PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50345579(5-((5-(4-((4-(2-hydroxyethyl)piperazin-1-yl)methyl...)copy SMILEScopy InChI
Affinity DataIC50: 6.40nMAssay Description:Inhibition of human CDK2/Cyclin E using Histone H1 substrate by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0MM8PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50345579(5-((5-(4-((4-(2-hydroxyethyl)piperazin-1-yl)methyl...)copy SMILEScopy InChI
Affinity DataIC50: 7.20nMAssay Description:Inhibition of human FMS using poly[Glu:Tyr] by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0MM8PubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50322535(3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N...)copy SMILEScopy InChI
Affinity DataIC50: 8.60nMAssay Description:Inhibition of wild type human ABL using [EAIYAAPFAKKK] peptide substrate by Hotspot assayMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50345579(5-((5-(4-((4-(2-hydroxyethyl)piperazin-1-yl)methyl...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of human FGFR3 using poly[Glu:Tyr] peptide substrate by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0MM8PubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50345580(3-((2-acetamidothiazol-5-yl)ethynyl)-4-methyl-N-(4...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of wild type human ABL using [EAIYAAPFAKKK] peptide substrate by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0MM8PubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50345586(CHEMBL1784635 | N,1-dimethyl-5-((2-methyl-5-(4-((4...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of wild type human ABL using [EAIYAAPFAKKK] peptide substrate by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0MM8PubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50345594(3-((6-acetamidopyridin-3-yl)ethynyl)-4-methyl-N-(4...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of wild type human ABL using [EAIYAAPFAKKK] peptide substrate by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0MM8PubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50345579(5-((5-(4-((4-(2-hydroxyethyl)piperazin-1-yl)methyl...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human BRAF using MEK1 (K97R), ATP substrate by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0MM8PubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50345593(4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of wild type human ABL using [EAIYAAPFAKKK] peptide substrate by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0MM8PubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50345581(3-((2-aminothiazol-5-yl)ethynyl)-4-methyl-N-(4-((4...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of wild type human ABL using [EAIYAAPFAKKK] peptide substrate by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0MM8PubMed
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50345579(5-((5-(4-((4-(2-hydroxyethyl)piperazin-1-yl)methyl...)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of human FGFR4 using poly[Glu:Tyr] peptide substrate by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0MM8PubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50345596(4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of wild type human ABL using [EAIYAAPFAKKK] peptide substrate by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0MM8PubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50345592(5-((2-methyl-5-(4-((4-methylpiperazin-1-yl)methyl)...)copy SMILEScopy InChI
Affinity DataIC50: 49nMAssay Description:Inhibition of wild type human ABL using [EAIYAAPFAKKK] peptide substrate by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0MM8PubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50345591(3-((2-(cyclopropylamino)pyrimidin-5-yl)ethynyl)-4-...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of wild type human ABL using [EAIYAAPFAKKK] peptide substrate by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0MM8PubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50345579(5-((5-(4-((4-(2-hydroxyethyl)piperazin-1-yl)methyl...)copy SMILEScopy InChI
Affinity DataIC50: 55nMAssay Description:Inhibition of human JAK1 using poly[Glu:Tyr] by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0MM8PubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50345585(CHEMBL1784636 | N-(2-hydroxyethyl)-1-methyl-5-((2-...)copy SMILEScopy InChI
Affinity DataIC50: 55nMAssay Description:Inhibition of wild type human ABL using [EAIYAAPFAKKK] peptide substrate by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0MM8PubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50345579(5-((5-(4-((4-(2-hydroxyethyl)piperazin-1-yl)methyl...)copy SMILEScopy InChI
Affinity DataIC50: 58nMAssay Description:Inhibition of human JAK3 using GEEEEYFELVKKKK peptide substrate by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0MM8PubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50345595(4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(...)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Inhibition of wild type human ABL using [EAIYAAPFAKKK] peptide substrate by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0MM8PubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50345588(3-((1,2-dimethyl-1H-imidazol-5-yl)ethynyl)-4-methy...)copy SMILEScopy InChI
Affinity DataIC50: 73nMAssay Description:Inhibition of wild type human ABL using [EAIYAAPFAKKK] peptide substrate by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0MM8PubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50345589(4-methyl-3-((1-methyl-1H-imidazol-5-yl)ethynyl)-N-...)copy SMILEScopy InChI
Affinity DataIC50: 129nMAssay Description:Inhibition of wild type human ABL using [EAIYAAPFAKKK] peptide substrate by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0MM8PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50345579(5-((5-(4-((4-(2-hydroxyethyl)piperazin-1-yl)methyl...)copy SMILEScopy InChI
Affinity DataIC50: 536nMAssay Description:Inhibition of human JAK2 using poly[Glu:Tyr] by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0MM8PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50345579(5-((5-(4-((4-(2-hydroxyethyl)piperazin-1-yl)methyl...)copy SMILEScopy InChI
Affinity DataIC50: 736nMAssay Description:Inhibition of human EGFR using poly[Glu:Tyr] by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0MM8PubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50345590(3-((1H-imidazol-5-yl)ethynyl)-4-methyl-N-(4-((4-me...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of wild type human ABL using [EAIYAAPFAKKK] peptide substrate by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0MM8PubMed
TargetAurora kinase A(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50345579(5-((5-(4-((4-(2-hydroxyethyl)piperazin-1-yl)methyl...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human Aurora A using H-LRRASLG peptide substrate by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0MM8PubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50345579(5-((5-(4-((4-(2-hydroxyethyl)piperazin-1-yl)methyl...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human c-Met using KKKSPGEYVNIEFG peptide substrate by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0MM8PubMed
TargetInsulin receptor(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50345579(5-((5-(4-((4-(2-hydroxyethyl)piperazin-1-yl)methyl...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human IR using poly[Glu:Tyr] by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0MM8PubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50345579(5-((5-(4-((4-(2-hydroxyethyl)piperazin-1-yl)methyl...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human c-Kit using poly[Glu:Tyr] by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0MM8PubMed