Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with all data for entry = 50033705
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Sun Yat-sen University

Curated by ChEMBL
LigandPNGBDBM50349933(CHEMBL1812144)copy SMILEScopy InChI
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibition of human topoisomerase 2 alpha-mediated relaxation of supercoiled pBR322 DNA after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2513ZJDPubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Sun Yat-sen University

Curated by ChEMBL
LigandPNGBDBM50349934(CHEMBL1812139)copy SMILEScopy InChI
Affinity DataIC50: 1.88E+3nMAssay Description:Inhibition of human topoisomerase 2 alpha-mediated relaxation of supercoiled pBR322 DNA after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2513ZJDPubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Sun Yat-sen University

Curated by ChEMBL
LigandPNGBDBM50349932(CHEMBL1812137)copy SMILEScopy InChI
Affinity DataIC50: 4.88E+3nMAssay Description:Inhibition of human topoisomerase 2 alpha-mediated relaxation of supercoiled pBR322 DNA after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2513ZJDPubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Sun Yat-sen University

Curated by ChEMBL
LigandPNGBDBM50127140((-)-etoposide | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...)copy SMILEScopy InChI
Affinity DataIC50: 6.03E+4nMAssay Description:Inhibition of human topoisomerase 2 alpha-mediated relaxation of supercoiled pBR322 DNA after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair