Compile Data Set for Download or QSAR
Found 41 Enz. Inhib. hit(s) with all data for entry = 50033756
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50182801((3R,4R,5R)-5-(Hydroxymethyl)piperidine-3,4-diol, 8...)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Inhibition of human lysosome beta-glucosidase assessed as production of 4-methylumbelliferone using 4-methylumbelliferyl beta-D-glucoside as substrat...More data for this Ligand-Target Pair
TargetLactase/phlorizin hydrolase(Rattus norvegicus)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50182801((3R,4R,5R)-5-(Hydroxymethyl)piperidine-3,4-diol, 8...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of rat intestinal lactase assessed as production of p-nitrophenol by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC3ZWWPubMed
TargetSucrase-isomaltase, intestinal(Rattus norvegicus (Rat))
University of Toyama

Curated by ChEMBL
LigandPNGBDBM18351((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)copy SMILEScopy InChI
Affinity DataIC50: 510nMAssay Description:Inhibition of rat intestinal sucrase assessed as production of p-nitrophenol at by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC3ZWWPubMed
TargetLactase/phlorizin hydrolase(Rattus norvegicus)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50350758(CHEMBL1818433)copy SMILEScopy InChI
Affinity DataIC50: 510nMAssay Description:Inhibition of rat intestinal lactase assessed as production of p-nitrophenol by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC3ZWWPubMed
TargetSucrase-isomaltase, intestinal(Rattus norvegicus (Rat))
University of Toyama

Curated by ChEMBL
LigandPNGBDBM18351((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)copy SMILEScopy InChI
Affinity DataIC50: 650nMAssay Description:Inhibition of rat intestinal isomaltase assessed as production of p-nitrophenol at by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC3ZWWPubMed
TargetBeta-galactosidase(Bos taurus (Bovine))
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50292389(3-epi-fagomine | 3-epifagomine | CHEMBL456583)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of bovine liver beta-galactosidase assessed as production of p-nitrophenol by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC3ZWWPubMed
TargetBeta-galactosidase(Bos taurus (Bovine))
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50182801((3R,4R,5R)-5-(Hydroxymethyl)piperidine-3,4-diol, 8...)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of bovine liver beta-galactosidase assessed as production of p-nitrophenol by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC3ZWWPubMed
TargetLactase/phlorizin hydrolase(Rattus norvegicus)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50292389(3-epi-fagomine | 3-epifagomine | CHEMBL456583)copy SMILEScopy InChI
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of rat intestinal lactase assessed as production of p-nitrophenol by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC3ZWWPubMed
TargetLysosomal acid glucosylceramidase(Bos taurus)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50292389(3-epi-fagomine | 3-epifagomine | CHEMBL456583)copy SMILEScopy InChI
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of bovine liver beta-glucosidase assessed as production of 4-methylumbelliferone using 4-methylumbelliferyl beta-D-glucoside as substrate ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC3ZWWPubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50263043(CHEMBL501385 | L-Isofagomine)copy SMILEScopy InChI
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of human lysosome beta-glucosidase assessed as production of 4-methylumbelliferone using 4-methylumbelliferyl beta-D-glucoside as substrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC3ZWWPubMed
TargetSucrase-isomaltase, intestinal(Rattus norvegicus (Rat))
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50163447((2S,3S,4S,5R)-2-Hydroxymethyl-piperidine-3,4,5-tri...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of rat intestinal sucrase assessed as production of p-nitrophenol at by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC3ZWWPubMed
TargetLactase/phlorizin hydrolase(Rattus norvegicus)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50263043(CHEMBL501385 | L-Isofagomine)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of rat intestinal lactase assessed as production of p-nitrophenol by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC3ZWWPubMed
TargetBeta-galactosidase(Bos taurus (Bovine))
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50350758(CHEMBL1818433)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of bovine liver beta-galactosidase assessed as production of p-nitrophenol by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC3ZWWPubMed
TargetLysosomal acid glucosylceramidase(Bos taurus)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50182801((3R,4R,5R)-5-(Hydroxymethyl)piperidine-3,4-diol, 8...)copy SMILEScopy InChI
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of bovine liver beta-glucosidase assessed as production of 4-methylumbelliferone using 4-methylumbelliferyl beta-D-glucoside as substrate ...More data for this Ligand-Target Pair
TargetSucrase-isomaltase, intestinal(Rattus norvegicus (Rat))
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50240725((2R,3R,4R)-2-Hydroxymethyl-piperidine-3,4-diol | C...)copy SMILEScopy InChI
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of rat intestinal sucrase assessed as production of p-nitrophenol at by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC3ZWWPubMed
TargetSucrase-isomaltase, intestinal(Rattus norvegicus (Rat))
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50263043(CHEMBL501385 | L-Isofagomine)copy SMILEScopy InChI
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of rat intestinal sucrase assessed as production of p-nitrophenol at by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC3ZWWPubMed
TargetSucrase-isomaltase, intestinal(Rattus norvegicus (Rat))
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50240725((2R,3R,4R)-2-Hydroxymethyl-piperidine-3,4-diol | C...)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of rat intestinal isomaltase assessed as production of p-nitrophenol at by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC3ZWWPubMed
TargetBeta-galactosidase(Bos taurus (Bovine))
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50240725((2R,3R,4R)-2-Hydroxymethyl-piperidine-3,4-diol | C...)copy SMILEScopy InChI
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of bovine liver beta-galactosidase assessed as production of p-nitrophenol by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC3ZWWPubMed
TargetLactase/phlorizin hydrolase(Rattus norvegicus)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM18351((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)copy SMILEScopy InChI
Affinity DataIC50: 4.90E+4nMAssay Description:Inhibition of rat intestinal lactase assessed as production of p-nitrophenol by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC3ZWWPubMed
TargetLactase/phlorizin hydrolase(Rattus norvegicus)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50350761(CHEMBL1818321)copy SMILEScopy InChI
Affinity DataIC50: 5.20E+4nMAssay Description:Inhibition of rat intestinal lactase assessed as production of p-nitrophenol by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC3ZWWPubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50350758(CHEMBL1818433)copy SMILEScopy InChI
Affinity DataIC50: 5.40E+4nMAssay Description:Inhibition of human lysosome beta-glucosidase assessed as production of 4-methylumbelliferone using 4-methylumbelliferyl beta-D-glucoside as substrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC3ZWWPubMed
TargetLysosomal acid glucosylceramidase(Bos taurus)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50350758(CHEMBL1818433)copy SMILEScopy InChI
Affinity DataIC50: 6.30E+4nMAssay Description:Inhibition of bovine liver beta-glucosidase assessed as production of 4-methylumbelliferone using 4-methylumbelliferyl beta-D-glucoside as substrate ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC3ZWWPubMed
TargetLactase/phlorizin hydrolase(Rattus norvegicus)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50350759(CHEMBL1818434)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+4nMAssay Description:Inhibition of rat intestinal lactase assessed as production of p-nitrophenol by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC3ZWWPubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50350761(CHEMBL1818321)copy SMILEScopy InChI
Affinity DataIC50: 1.13E+5nMAssay Description:Inhibition of human lysosome beta-glucosidase assessed as production of 4-methylumbelliferone using 4-methylumbelliferyl beta-D-glucoside as substrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC3ZWWPubMed
TargetLactase/phlorizin hydrolase(Rattus norvegicus)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50350760(CHEMBL1818436)copy SMILEScopy InChI
Affinity DataIC50: 1.22E+5nMAssay Description:Inhibition of rat intestinal lactase assessed as production of p-nitrophenol by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC3ZWWPubMed
TargetSucrase-isomaltase, intestinal(Rattus norvegicus (Rat))
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50163447((2S,3S,4S,5R)-2-Hydroxymethyl-piperidine-3,4,5-tri...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of rat intestinal isomaltase assessed as production of p-nitrophenol at by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC3ZWWPubMed
TargetLactase/phlorizin hydrolase(Rattus norvegicus)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50350756(CHEMBL1818323)copy SMILEScopy InChI
Affinity DataIC50: 2.11E+5nMAssay Description:Inhibition of rat intestinal lactase assessed as production of p-nitrophenol by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC3ZWWPubMed
TargetSucrase-isomaltase, intestinal(Rattus norvegicus (Rat))
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50350760(CHEMBL1818436)copy SMILEScopy InChI
Affinity DataIC50: 2.25E+5nMAssay Description:Inhibition of rat intestinal sucrase assessed as production of p-nitrophenol at by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC3ZWWPubMed
TargetLysosomal acid glucosylceramidase(Bos taurus)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50240725((2R,3R,4R)-2-Hydroxymethyl-piperidine-3,4-diol | C...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of bovine liver beta-glucosidase assessed as production of 4-methylumbelliferone using 4-methylumbelliferyl beta-D-glucoside as substrate ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC3ZWWPubMed
TargetTissue alpha-L-fucosidase(Bos taurus)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50350760(CHEMBL1818436)copy SMILEScopy InChI
Affinity DataIC50: 2.60E+5nMAssay Description:Inhibition of bovine epididymis alpha-L-fucosidase assessed as production of p-nitrophenol by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC3ZWWPubMed
TargetSucrase-isomaltase, intestinal(Rattus norvegicus (Rat))
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50182801((3R,4R,5R)-5-(Hydroxymethyl)piperidine-3,4-diol, 8...)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+5nMAssay Description:Inhibition of rat intestinal isomaltase assessed as production of p-nitrophenol at by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC3ZWWPubMed
TargetLactase/phlorizin hydrolase(Rattus norvegicus)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50163447((2S,3S,4S,5R)-2-Hydroxymethyl-piperidine-3,4,5-tri...)copy SMILEScopy InChI
Affinity DataIC50: 3.17E+5nMAssay Description:Inhibition of rat intestinal lactase assessed as production of p-nitrophenol by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC3ZWWPubMed
TargetBeta-galactosidase(Bos taurus (Bovine))
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50350757(CHEMBL1818432)copy SMILEScopy InChI
Affinity DataIC50: 3.89E+5nMAssay Description:Inhibition of bovine liver beta-galactosidase assessed as production of p-nitrophenol by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC3ZWWPubMed
TargetLactase/phlorizin hydrolase(Rattus norvegicus)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50350762(CHEMBL1818322)copy SMILEScopy InChI
Affinity DataIC50: 4.69E+5nMAssay Description:Inhibition of rat intestinal lactase assessed as production of p-nitrophenol by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC3ZWWPubMed
TargetSucrase-isomaltase, intestinal(Rattus norvegicus (Rat))
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50182801((3R,4R,5R)-5-(Hydroxymethyl)piperidine-3,4-diol, 8...)copy SMILEScopy InChI
Affinity DataIC50: 5.31E+5nMAssay Description:Inhibition of rat intestinal sucrase assessed as production of p-nitrophenol at by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC3ZWWPubMed
TargetBeta-galactosidase(Bos taurus (Bovine))
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50163447((2S,3S,4S,5R)-2-Hydroxymethyl-piperidine-3,4,5-tri...)copy SMILEScopy InChI
Affinity DataIC50: 5.60E+5nMAssay Description:Inhibition of bovine liver beta-galactosidase assessed as production of p-nitrophenol by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC3ZWWPubMed
TargetLysosomal acid glucosylceramidase(Bos taurus)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50263043(CHEMBL501385 | L-Isofagomine)copy SMILEScopy InChI
Affinity DataIC50: 6.11E+5nMAssay Description:Inhibition of bovine liver beta-glucosidase assessed as production of 4-methylumbelliferone using 4-methylumbelliferyl beta-D-glucoside as substrate ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC3ZWWPubMed
TargetLactase/phlorizin hydrolase(Rattus norvegicus)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50350757(CHEMBL1818432)copy SMILEScopy InChI
Affinity DataIC50: 6.46E+5nMAssay Description:Inhibition of rat intestinal lactase assessed as production of p-nitrophenol by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC3ZWWPubMed
TargetLysosomal acid glucosylceramidase(Bos taurus)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50350757(CHEMBL1818432)copy SMILEScopy InChI
Affinity DataIC50: 6.76E+5nMAssay Description:Inhibition of bovine liver beta-glucosidase assessed as production of 4-methylumbelliferone using 4-methylumbelliferyl beta-D-glucoside as substrate ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC3ZWWPubMed
TargetBeta-galactosidase(Bos taurus (Bovine))
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50263043(CHEMBL501385 | L-Isofagomine)copy SMILEScopy InChI
Affinity DataIC50: 8.21E+5nMAssay Description:Inhibition of bovine liver beta-galactosidase assessed as production of p-nitrophenol by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC3ZWWPubMed
TargetBeta-galactosidase(Bos taurus (Bovine))
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50350760(CHEMBL1818436)copy SMILEScopy InChI
Affinity DataIC50: 9.60E+5nMAssay Description:Inhibition of bovine liver beta-galactosidase assessed as production of p-nitrophenol by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC3ZWWPubMed