Compile Data Set for Download or QSAR
Found 115 Enz. Inhib. hit(s) with all data for entry = 50033842
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352418(CHEMBL1823863)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352419(CHEMBL1823864)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352296(CHEMBL1822468)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352419(CHEMBL1823864)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of of Bodipy-labelled cyclopamine binding to Smo expressed in COS-1 cells in presence of 20% NHS after 4 to 6 hrs by FACS flow cytometric ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352418(CHEMBL1823863)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of of Bodipy-labelled cyclopamine binding to Smo expressed in COS-1 cells in presence of 20% NHS after 4 to 6 hrs by FACS flow cytometric ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352296(CHEMBL1822468)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Inhibition of of Bodipy-labelled cyclopamine binding to Smo expressed in COS-1 cells in presence of 20% NHS after 4 to 6 hrs by FACS flow cytometric ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352420(CHEMBL1823865)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352433(CHEMBL1823821)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352421(CHEMBL1823591)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352424(CHEMBL1823579)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352420(CHEMBL1823865)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of of Bodipy-labelled cyclopamine binding to Smo expressed in COS-1 cells in presence of 20% NHS after 4 to 6 hrs by FACS flow cytometric ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352435(CHEMBL1823825)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352397(CHEMBL1823842)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352396(CHEMBL1823841)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352400(CHEMBL1823845)copy SMILEScopy InChI
Affinity DataIC50: 320nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352439(CHEMBL1823831)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352416(CHEMBL1823861)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352440(CHEMBL1823832)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352423(CHEMBL1823584)copy SMILEScopy InChI
Affinity DataIC50: 380nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352395(CHEMBL1823840)copy SMILEScopy InChI
Affinity DataIC50: 420nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352477(CHEMBL1823830)copy SMILEScopy InChI
Affinity DataIC50: 470nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352415(CHEMBL1823860)copy SMILEScopy InChI
Affinity DataIC50: 480nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352475(CHEMBL1823824)copy SMILEScopy InChI
Affinity DataIC50: 480nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352441(CHEMBL1823833)copy SMILEScopy InChI
Affinity DataIC50: 490nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352437(CHEMBL1823828)copy SMILEScopy InChI
Affinity DataIC50: 510nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352428(CHEMBL1823587)copy SMILEScopy InChI
Affinity DataIC50: 620nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352427(CHEMBL1823586)copy SMILEScopy InChI
Affinity DataIC50: 640nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352438(CHEMBL1823829)copy SMILEScopy InChI
Affinity DataIC50: 670nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352417(CHEMBL1823862)copy SMILEScopy InChI
Affinity DataIC50: 690nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352421(CHEMBL1823591)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:Inhibition of of Bodipy-labelled cyclopamine binding to Smo expressed in COS-1 cells in presence of 20% NHS after 4 to 6 hrs by FACS flow cytometric ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352457(CHEMBL1823602)copy SMILEScopy InChI
Affinity DataIC50: 750nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352394(CHEMBL1823839)copy SMILEScopy InChI
Affinity DataIC50: 750nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352417(CHEMBL1823862)copy SMILEScopy InChI
Affinity DataIC50: 760nMAssay Description:Inhibition of of Bodipy-labelled cyclopamine binding to Smo expressed in COS-1 cells in presence of 20% NHS after 4 to 6 hrs by FACS flow cytometric ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352426(CHEMBL1823585)copy SMILEScopy InChI
Affinity DataIC50: 790nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352414(CHEMBL1823859)copy SMILEScopy InChI
Affinity DataIC50: 860nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352432(CHEMBL1823617)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352431(CHEMBL1823590)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352422(CHEMBL1823616)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352467(CHEMBL1823612)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352416(CHEMBL1823861)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of of Bodipy-labelled cyclopamine binding to Smo expressed in COS-1 cells in presence of 20% NHS after 4 to 6 hrs by FACS flow cytometric ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352444(CHEMBL1823836)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352399(CHEMBL1823844)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352412(CHEMBL1823857)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of of Bodipy-labelled cyclopamine binding to Smo expressed in COS-1 cells in presence of 20% NHS after 4 to 6 hrs by FACS flow cytometric ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352442(CHEMBL1823834)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352436(CHEMBL1823827)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352443(CHEMBL1823835)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352415(CHEMBL1823860)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of of Bodipy-labelled cyclopamine binding to Smo expressed in COS-1 cells in presence of 20% NHS after 4 to 6 hrs by FACS flow cytometric ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352398(CHEMBL1823843)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352446(CHEMBL1823838)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352414(CHEMBL1823859)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of of Bodipy-labelled cyclopamine binding to Smo expressed in COS-1 cells in presence of 20% NHS after 4 to 6 hrs by FACS flow cytometric ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
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