Compile Data Set for Download or QSAR
Found 18 Enz. Inhib. hit(s) with all data for entry = 50033936
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50354121(CHEMBL1836238)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Inhibition of hypoxia-induced HIF1alpha activation in human ME180 cells by HRE3-Bla-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70G65PubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50354120(CHEMBL1836239)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition of hypoxia-induced HIF1alpha activation in human ME180 cells by HRE3-Bla-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70G65PubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50354128(CHEMBL1836179)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of hypoxia-induced HIF1alpha activation in human ME180 cells by HRE3-Bla-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70G65PubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50354125(CHEMBL1345685)copy SMILEScopy InChI
Affinity DataIC50: 430nMAssay Description:Inhibition of hypoxia-induced HIF1alpha activation in human ME180 cells by HRE3-Bla-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70G65PubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50354119(CHEMBL1836233)copy SMILEScopy InChI
Affinity DataIC50: 470nMAssay Description:Inhibition of hypoxia-induced HIF1alpha activation in human ME180 cells by HRE3-Bla-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70G65PubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50354126(CHEMBL1836236)copy SMILEScopy InChI
Affinity DataIC50: 810nMAssay Description:Inhibition of hypoxia-induced HIF1alpha activation in human ME180 cells by HRE3-Bla-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70G65PubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50354122(CHEMBL1836230)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of hypoxia-induced HIF1alpha activation in human ME180 cells by HRE3-Bla-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70G65PubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50354117(CHEMBL1836234)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of hypoxia-induced HIF1alpha activation in human ME180 cells by HRE3-Bla-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70G65PubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50354127(CHEMBL1836177)copy SMILEScopy InChI
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of hypoxia-induced HIF1alpha activation in human ME180 cells by HRE3-Bla-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70G65PubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50354133(CHEMBL1836184)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of hypoxia-induced HIF1alpha activation in human ME180 cells by HRE3-Bla-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70G65PubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50354130(CHEMBL1836181)copy SMILEScopy InChI
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of hypoxia-induced HIF1alpha activation in human ME180 cells by HRE3-Bla-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70G65PubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50354129(CHEMBL1836180)copy SMILEScopy InChI
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of hypoxia-induced HIF1alpha activation in human ME180 cells by HRE3-Bla-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70G65PubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50354132(CHEMBL1836183)copy SMILEScopy InChI
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of hypoxia-induced HIF1alpha activation in human ME180 cells by HRE3-Bla-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70G65PubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50354116(CHEMBL1836235)copy SMILEScopy InChI
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of hypoxia-induced HIF1alpha activation in human ME180 cells by HRE3-Bla-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70G65PubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50354131(CHEMBL1836182)copy SMILEScopy InChI
Affinity DataIC50: 2.29E+4nMAssay Description:Inhibition of hypoxia-induced HIF1alpha activation in human ME180 cells by HRE3-Bla-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70G65PubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50354124(CHEMBL1836237)copy SMILEScopy InChI
Affinity DataIC50: 2.75E+4nMAssay Description:Inhibition of hypoxia-induced HIF1alpha activation in human ME180 cells by HRE3-Bla-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70G65PubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50354123(CHEMBL1833996)copy SMILEScopy InChI
Affinity DataIC50: 2.76E+4nMAssay Description:Inhibition of hypoxia-induced HIF1alpha activation in human ME180 cells by HRE3-Bla-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70G65PubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50354118(CHEMBL1836240)copy SMILEScopy InChI
Affinity DataIC50: 2.76E+4nMAssay Description:Inhibition of hypoxia-induced HIF1alpha activation in human ME180 cells by HRE3-Bla-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70G65PubMed