Compile Data Set for Download or QSAR
Found 28 Enz. Inhib. hit(s) with all data for entry = 50033960
Target72 kDa type IV collagenase(Homo sapiens (Human))
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50354624(CHEMBL1834422 | US10357546, ND-322 | US9951035, ND...)copy SMILEScopy InChI
Affinity DataKi:  24nMAssay Description:Inhibition of human recombinant MMP2 assessed as hydrolysis of MOCAcPLGLA2pr(Dnp)AR-NH2 by fluorescence spectrofluorometry More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79BSMPubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50354622(CHEMBL1834418)copy SMILEScopy InChI
Affinity DataKi:  62nMAssay Description:Inhibition of human recombinant MMP2 assessed as hydrolysis of MOCAcPLGLA2pr(Dnp)AR-NH2 by fluorescence spectrofluorometry More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79BSMPubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50354628(CHEMBL1834419)copy SMILEScopy InChI
Affinity DataKi:  69nMAssay Description:Inhibition of human recombinant MMP2 assessed as hydrolysis of MOCAcPLGLA2pr(Dnp)AR-NH2 by fluorescence spectrofluorometry More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79BSMPubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50264811(CHEMBL485492 | N-(4-(4-(thiiran-2-ylmethylsulfonyl...)copy SMILEScopy InChI
Affinity DataKi:  130nMAssay Description:Inhibition of human recombinant MMP9 catalytic domain assessed as hydrolysis of MOCAcPLGLA2pr(Dnp)AR-NH2 by fluorescence spectrofluorometry More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79BSMPubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50264811(CHEMBL485492 | N-(4-(4-(thiiran-2-ylmethylsulfonyl...)copy SMILEScopy InChI
Affinity DataKi:  130nMAssay Description:Inhibition of human recombinant MMP9 assessed as hydrolysis of MOCAcPLGLA2pr(Dnp)AR-NH2 by fluorescence spectrofluorometry More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79BSMPubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50354624(CHEMBL1834422 | US10357546, ND-322 | US9951035, ND...)copy SMILEScopy InChI
Affinity DataKi:  210nMAssay Description:Inhibition of human recombinant MMP14 catalytic domain assessed as hydrolysis of MOCAcPLGLA2pr(Dnp)AR-NH2 by fluorescence spectrofluorometry More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79BSMPubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50354625(CHEMBL1834423)copy SMILEScopy InChI
Affinity DataKi:  260nMAssay Description:Inhibition of human recombinant MMP14 catalytic domain assessed as hydrolysis of MOCAcPLGLA2pr(Dnp)AR-NH2 by fluorescence spectrofluorometry More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79BSMPubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50354626(CHEMBL1834421)copy SMILEScopy InChI
Affinity DataKi:  420nMAssay Description:Inhibition of human recombinant MMP2 assessed as hydrolysis of MOCAcPLGLA2pr(Dnp)AR-NH2 by fluorescence spectrofluorometry More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79BSMPubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50354623(CHEMBL1834417)copy SMILEScopy InChI
Affinity DataKi:  440nMAssay Description:Inhibition of human recombinant MMP2 assessed as hydrolysis of MOCAcPLGLA2pr(Dnp)AR-NH2 by fluorescence spectrofluorometry More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79BSMPubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50354627(CHEMBL1834420)copy SMILEScopy InChI
Affinity DataKi:  520nMAssay Description:Inhibition of human recombinant MMP2 assessed as hydrolysis of MOCAcPLGLA2pr(Dnp)AR-NH2 by fluorescence spectrofluorometry More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79BSMPubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50264811(CHEMBL485492 | N-(4-(4-(thiiran-2-ylmethylsulfonyl...)copy SMILEScopy InChI
Affinity DataKi:  680nMAssay Description:Inhibition of human recombinant MMP14 assessed as hydrolysis of MOCAcPLGLA2pr(Dnp)AR-NH2 by fluorescence spectrofluorometry More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79BSMPubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50354624(CHEMBL1834422 | US10357546, ND-322 | US9951035, ND...)copy SMILEScopy InChI
Affinity DataKi:  870nMAssay Description:Inhibition of human recombinant MMP9 catalytic domain assessed as hydrolysis of MOCAcPLGLA2pr(Dnp)AR-NH2 by fluorescence spectrofluorometry More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79BSMPubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50354622(CHEMBL1834418)copy SMILEScopy InChI
Affinity DataKi:  1.60E+3nMAssay Description:Inhibition of human recombinant MMP9 catalytic domain assessed as hydrolysis of MOCAcPLGLA2pr(Dnp)AR-NH2 by fluorescence spectrofluorometry More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79BSMPubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50354623(CHEMBL1834417)copy SMILEScopy InChI
Affinity DataKi:  3.10E+3nMAssay Description:Inhibition of human recombinant MMP9 catalytic domain assessed as hydrolysis of MOCAcPLGLA2pr(Dnp)AR-NH2 by fluorescence spectrofluorometry More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79BSMPubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50354628(CHEMBL1834419)copy SMILEScopy InChI
Affinity DataKi:  4.30E+3nMAssay Description:Inhibition of human recombinant MMP9 catalytic domain assessed as hydrolysis of MOCAcPLGLA2pr(Dnp)AR-NH2 by fluorescence spectrofluorometry More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79BSMPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50264811(CHEMBL485492 | N-(4-(4-(thiiran-2-ylmethylsulfonyl...)copy SMILEScopy InChI
Affinity DataKi:  5.40E+3nMAssay Description:Inhibition of human recombinant MMP1 assessed as hydrolysis of MOCAcPLGLA2pr(Dnp)AR-NH2 by fluorescence spectrofluorometry More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79BSMPubMed
TargetStromelysin-1(Homo sapiens (Human))
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50264811(CHEMBL485492 | N-(4-(4-(thiiran-2-ylmethylsulfonyl...)copy SMILEScopy InChI
Affinity DataKi:  1.22E+4nMAssay Description:Inhibition of human recombinant MMP3 assessed as hydrolysis of MOCAcPLGLA2pr(Dnp)AR-NH2 by fluorescence spectrofluorometry More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79BSMPubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50354626(CHEMBL1834421)copy SMILEScopy InChI
Affinity DataKi:  1.87E+4nMAssay Description:Inhibition of human recombinant MMP9 catalytic domain assessed as hydrolysis of MOCAcPLGLA2pr(Dnp)AR-NH2 by fluorescence spectrofluorometry More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79BSMPubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50354627(CHEMBL1834420)copy SMILEScopy InChI
Affinity DataKi:  1.96E+4nMAssay Description:Inhibition of human recombinant MMP9 catalytic domain assessed as hydrolysis of MOCAcPLGLA2pr(Dnp)AR-NH2 by fluorescence spectrofluorometry More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79BSMPubMed
TargetStromelysin-1(Homo sapiens (Human))
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50354624(CHEMBL1834422 | US10357546, ND-322 | US9951035, ND...)copy SMILEScopy InChI
Affinity DataKi:  2.34E+4nMAssay Description:Inhibition of human recombinant MMP3 catalytic domain assessed as hydrolysis of MOCAcPLGLA2pr(Dnp)AR-NH2 by fluorescence spectrofluorometry More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79BSMPubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50354627(CHEMBL1834420)copy SMILEScopy InChI
Affinity DataKi:  2.89E+4nMAssay Description:Inhibition of human recombinant MMP14 catalytic domain assessed as hydrolysis of MOCAcPLGLA2pr(Dnp)AR-NH2 by fluorescence spectrofluorometry More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79BSMPubMed
TargetMatrilysin(Homo sapiens (Human))
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50264811(CHEMBL485492 | N-(4-(4-(thiiran-2-ylmethylsulfonyl...)copy SMILEScopy InChI
Affinity DataKi:  3.90E+4nMAssay Description:Inhibition of human recombinant MMP7 assessed as hydrolysis of MOCAcPLGLA2pr(Dnp)AR-NH2 by fluorescence spectrofluorometry More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79BSMPubMed
TargetStromelysin-1(Homo sapiens (Human))
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50354627(CHEMBL1834420)copy SMILEScopy InChI
Affinity DataKi:  4.05E+4nMAssay Description:Inhibition of human recombinant MMP3 catalytic domain assessed as hydrolysis of MOCAcPLGLA2pr(Dnp)AR-NH2 by fluorescence spectrofluorometry More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79BSMPubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50354625(CHEMBL1834423)copy SMILEScopy InChI
Affinity DataKi:  7.80E+4nMAssay Description:Inhibition of human recombinant MMP2 assessed as hydrolysis of MOCAcPLGLA2pr(Dnp)AR-NH2 by fluorescence spectrofluorometry More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79BSMPubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50264811(CHEMBL485492 | N-(4-(4-(thiiran-2-ylmethylsulfonyl...)copy SMILEScopy InChI
Affinity DataKi:  1.10E+5nMAssay Description:Inhibition of human recombinant MMP2 assessed as hydrolysis of MOCAcPLGLA2pr(Dnp)AR-NH2 by fluorescence spectrofluorometry More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79BSMPubMed
TargetMatrilysin(Homo sapiens (Human))
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50354625(CHEMBL1834423)copy SMILEScopy InChI
Affinity DataKi:  1.16E+5nMAssay Description:Inhibition of human recombinant MMP7 assessed as hydrolysis of MOCAcPLGLA2pr(Dnp)AR-NH2 by fluorescence spectrofluorometry More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79BSMPubMed
TargetMatrilysin(Homo sapiens (Human))
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50354627(CHEMBL1834420)copy SMILEScopy InChI
Affinity DataKi:  1.60E+5nMAssay Description:Inhibition of human recombinant MMP7 assessed as hydrolysis of MOCAcPLGLA2pr(Dnp)AR-NH2 by fluorescence spectrofluorometry More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79BSMPubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50354625(CHEMBL1834423)copy SMILEScopy InChI
Affinity DataKi:  4.90E+5nMAssay Description:Inhibition of human recombinant MMP9 catalytic domain assessed as hydrolysis of MOCAcPLGLA2pr(Dnp)AR-NH2 by fluorescence spectrofluorometry More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79BSMPubMed