Compile Data Set for Download or QSAR
Found 10 Enz. Inhib. hit(s) with all data for entry = 50034124
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Sanofi-Aventis Research and Development

Curated by ChEMBL
LigandPNGBDBM50357454(CHEMBL1917878)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of HSP90beta in human SKBR3 cells assessed as down regulation of HER2 expression levels after 24 hrs by FACS analysisMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Sanofi-Aventis Research and Development

Curated by ChEMBL
LigandPNGBDBM50357460(CHEMBL1917729)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:Inhibition of HSP90beta in human SKBR3 cells assessed as down regulation of HER2 expression levels after 24 hrs by FACS analysisMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Sanofi-Aventis Research and Development

Curated by ChEMBL
LigandPNGBDBM50357459(CHEMBL1917728)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of HSP90beta in human SKBR3 cells assessed as down regulation of HER2 expression levels after 24 hrs by FACS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR4XH4PubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Sanofi-Aventis Research and Development

Curated by ChEMBL
LigandPNGBDBM50357458(CHEMBL1917727)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of HSP90beta in human SKBR3 cells assessed as down regulation of HER2 expression levels after 24 hrs by FACS analysisMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Sanofi-Aventis Research and Development

Curated by ChEMBL
LigandPNGBDBM50357461(CHEMBL1917723)copy SMILEScopy InChI
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of human Hsp90beta after overnight incubation by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Sanofi-Aventis Research and Development

Curated by ChEMBL
LigandPNGBDBM50357456(CHEMBL1917725)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of HSP90beta in human SKBR3 cells assessed as down regulation of HER2 expression levels after 24 hrs by FACS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR4XH4PubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Sanofi-Aventis Research and Development

Curated by ChEMBL
LigandPNGBDBM50357455(CHEMBL1917724)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of HSP90beta in human SKBR3 cells assessed as down regulation of HER2 expression levels after 24 hrs by FACS analysisMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Sanofi-Aventis Research and Development

Curated by ChEMBL
LigandPNGBDBM50357457(CHEMBL1917726)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of HSP90beta in human SKBR3 cells assessed as down regulation of HER2 expression levels after 24 hrs by FACS analysisMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Sanofi-Aventis Research and Development

Curated by ChEMBL
LigandPNGBDBM50357454(CHEMBL1917878)copy SMILEScopy InChI
Affinity DataKd:  0.350nMAssay Description:Binding affinity to human Hsp90beta after overnight incubation by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Sanofi-Aventis Research and Development

Curated by ChEMBL
LigandPNGBDBM15359((4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14-...)copy SMILEScopy InChI
Affinity DataKd:  7.30nMAssay Description:Binding affinity to human Hsp90beta after overnight incubation by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR4XH4PubMed