Compile Data Set for Download or QSAR
Found 37 Enz. Inhib. hit(s) with all data for entry = 50034179
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50341760(2-Phenyl-5-trifluoromethyloxazole-4-carboxylic Aci...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of human DGAT1 using palmitoyl-1-14C coenzyme A and DAG as substrate after 1 hr by phospholipid flash plate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP53P6PubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50358323(CHEMBL1922582)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of human DGAT1 using palmitoyl-1-14C coenzyme A and DAG as substrate after 1 hr by phospholipid flash plate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP53P6PubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50358330(CHEMBL1922679)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of human DGAT1 using palmitoyl-1-14C coenzyme A and DAG as substrate after 1 hr by phospholipid flash plate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP53P6PubMed
TargetDiacylglycerol O-acyltransferase 1(Rattus norvegicus (rat))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50341760(2-Phenyl-5-trifluoromethyloxazole-4-carboxylic Aci...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of rat DGAT1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP53P6PubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50358333(CHEMBL1922682)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of human DGAT1 using palmitoyl-1-14C coenzyme A and DAG as substrate after 1 hr by phospholipid flash plate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP53P6PubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50358335(CHEMBL1922684)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of human DGAT1 using palmitoyl-1-14C coenzyme A and DAG as substrate after 1 hr by phospholipid flash plate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP53P6PubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50358328(CHEMBL1922677)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition of human DGAT1 using palmitoyl-1-14C coenzyme A and DAG as substrate after 1 hr by phospholipid flash plate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP53P6PubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50358337(CHEMBL1922686)copy SMILEScopy InChI
Affinity DataIC50: 253nMAssay Description:Inhibition of human DGAT1 using palmitoyl-1-14C coenzyme A and DAG as substrate after 1 hr by phospholipid flash plate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP53P6PubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50358327(CHEMBL1922676)copy SMILEScopy InChI
Affinity DataIC50: 330nMAssay Description:Inhibition of human DGAT1 using palmitoyl-1-14C coenzyme A and DAG as substrate after 1 hr by phospholipid flash plate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP53P6PubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50358329(CHEMBL1922678)copy SMILEScopy InChI
Affinity DataIC50: 380nMAssay Description:Inhibition of human DGAT1 using palmitoyl-1-14C coenzyme A and DAG as substrate after 1 hr by phospholipid flash plate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP53P6PubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50358338(CHEMBL1922687)copy SMILEScopy InChI
Affinity DataIC50: 407nMAssay Description:Inhibition of human DGAT1 using palmitoyl-1-14C coenzyme A and DAG as substrate after 1 hr by phospholipid flash plate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP53P6PubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50358339(CHEMBL1922688)copy SMILEScopy InChI
Affinity DataIC50: 554nMAssay Description:Inhibition of human DGAT1 using palmitoyl-1-14C coenzyme A and DAG as substrate after 1 hr by phospholipid flash plate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP53P6PubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50358331(CHEMBL1922680)copy SMILEScopy InChI
Affinity DataIC50: 610nMAssay Description:Inhibition of human DGAT1 using palmitoyl-1-14C coenzyme A and DAG as substrate after 1 hr by phospholipid flash plate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP53P6PubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50358340(CHEMBL1922689)copy SMILEScopy InChI
Affinity DataIC50: 653nMAssay Description:Inhibition of human DGAT1 using palmitoyl-1-14C coenzyme A and DAG as substrate after 1 hr by phospholipid flash plate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP53P6PubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50358334(CHEMBL1922683)copy SMILEScopy InChI
Affinity DataIC50: 660nMAssay Description:Inhibition of human DGAT1 using palmitoyl-1-14C coenzyme A and DAG as substrate after 1 hr by phospholipid flash plate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP53P6PubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50358341(CHEMBL1922690)copy SMILEScopy InChI
Affinity DataIC50: 699nMAssay Description:Inhibition of human DGAT1 using palmitoyl-1-14C coenzyme A and DAG as substrate after 1 hr by phospholipid flash plate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP53P6PubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50358332(CHEMBL1922681)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:Inhibition of human DGAT1 using palmitoyl-1-14C coenzyme A and DAG as substrate after 1 hr by phospholipid flash plate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP53P6PubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50358325(CHEMBL1922587)copy SMILEScopy InChI
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of human DGAT1 using palmitoyl-1-14C coenzyme A and DAG as substrate after 1 hr by phospholipid flash plate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP53P6PubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50358324(CHEMBL1922585)copy SMILEScopy InChI
Affinity DataIC50: 9.90E+3nMAssay Description:Inhibition of human DGAT1 using palmitoyl-1-14C coenzyme A and DAG as substrate after 1 hr by phospholipid flash plate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP53P6PubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50358326(CHEMBL1922589)copy SMILEScopy InChI
Affinity DataIC50: 1.39E+4nMAssay Description:Inhibition of human DGAT1 using palmitoyl-1-14C coenzyme A and DAG as substrate after 1 hr by phospholipid flash plate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP53P6PubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50358336(CHEMBL1922685)copy SMILEScopy InChI
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of human DGAT1 using palmitoyl-1-14C coenzyme A and DAG as substrate after 1 hr by phospholipid flash plate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP53P6PubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50358329(CHEMBL1922678)copy SMILEScopy InChI
Affinity DataEC50:  1.50E+3nMAssay Description:Inhibition of human DGAT1 expressed in CHOK1 cells using 14C palmitic acid as substrate after 1 hr by TLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP53P6PubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50358330(CHEMBL1922679)copy SMILEScopy InChI
Affinity DataEC50:  3.70E+3nMAssay Description:Inhibition of human DGAT1 expressed in CHOK1 cells using 14C palmitic acid as substrate after 1 hr by TLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP53P6PubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50358331(CHEMBL1922680)copy SMILEScopy InChI
Affinity DataEC50:  2.99E+3nMAssay Description:Inhibition of human DGAT1 expressed in CHOK1 cells using 14C palmitic acid as substrate after 1 hr by TLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP53P6PubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50358332(CHEMBL1922681)copy SMILEScopy InChI
Affinity DataEC50:  3.42E+3nMAssay Description:Inhibition of human DGAT1 expressed in CHOK1 cells using 14C palmitic acid as substrate after 1 hr by TLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP53P6PubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50358333(CHEMBL1922682)copy SMILEScopy InChI
Affinity DataEC50:  490nMAssay Description:Inhibition of human DGAT1 expressed in CHOK1 cells using 14C palmitic acid as substrate after 1 hr by TLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP53P6PubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50358334(CHEMBL1922683)copy SMILEScopy InChI
Affinity DataEC50:  1.18E+4nMAssay Description:Inhibition of human DGAT1 expressed in CHOK1 cells using 14C palmitic acid as substrate after 1 hr by TLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP53P6PubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50358335(CHEMBL1922684)copy SMILEScopy InChI
Affinity DataEC50:  7.46E+3nMAssay Description:Inhibition of human DGAT1 expressed in CHOK1 cells using 14C palmitic acid as substrate after 1 hr by TLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP53P6PubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50358337(CHEMBL1922686)copy SMILEScopy InChI
Affinity DataEC50:  910nMAssay Description:Inhibition of human DGAT1 expressed in CHOK1 cells using 14C palmitic acid as substrate after 1 hr by TLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP53P6PubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50358338(CHEMBL1922687)copy SMILEScopy InChI
Affinity DataEC50:  1.11E+4nMAssay Description:Inhibition of human DGAT1 expressed in CHOK1 cells using 14C palmitic acid as substrate after 1 hr by TLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP53P6PubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50358339(CHEMBL1922688)copy SMILEScopy InChI
Affinity DataEC50:  8.09E+3nMAssay Description:Inhibition of human DGAT1 expressed in CHOK1 cells using 14C palmitic acid as substrate after 1 hr by TLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP53P6PubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50341760(2-Phenyl-5-trifluoromethyloxazole-4-carboxylic Aci...)copy SMILEScopy InChI
Affinity DataEC50:  660nMAssay Description:Inhibition of human DGAT1 expressed in CHOK1 cells using 14C palmitic acid as substrate after 1 hr by TLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP53P6PubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50358340(CHEMBL1922689)copy SMILEScopy InChI
Affinity DataEC50:  8.90E+3nMAssay Description:Inhibition of human DGAT1 expressed in CHOK1 cells using 14C palmitic acid as substrate after 1 hr by TLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP53P6PubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50358341(CHEMBL1922690)copy SMILEScopy InChI
Affinity DataEC50: >2.50E+4nMAssay Description:Inhibition of human DGAT1 expressed in CHOK1 cells using 14C palmitic acid as substrate after 1 hr by TLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP53P6PubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50358328(CHEMBL1922677)copy SMILEScopy InChI
Affinity DataEC50:  840nMAssay Description:Inhibition of human DGAT1 expressed in CHOK1 cells using 14C palmitic acid as substrate after 1 hr by TLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP53P6PubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50358327(CHEMBL1922676)copy SMILEScopy InChI
Affinity DataEC50:  2.70E+3nMAssay Description:Inhibition of human DGAT1 expressed in CHOK1 cells using 14C palmitic acid as substrate after 1 hr by TLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP53P6PubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50358323(CHEMBL1922582)copy SMILEScopy InChI
Affinity DataEC50:  2.50E+3nMAssay Description:Inhibition of human DGAT1 expressed in CHOK1 cells using 14C palmitic acid as substrate after 1 hr by TLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP53P6PubMed