Compile Data Set for Download or QSAR
Found 25 Enz. Inhib. hit(s) with all data for entry = 50034425
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
M.S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50362181(({7-[2-(1H-1,2,3-benzotriazol-1-yl)-2-({6-bromo-7-...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of PTP1B assessed as para-nitrophenyl phosphate catalyzed hydrolysis of para-nitrophenol by p-NPP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X05PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
M.S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50362195(CHEMBL1938828)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of PTP1B assessed as para-nitrophenyl phosphate catalyzed hydrolysis of para-nitrophenol by p-NPP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X05PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
M.S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50362196(CHEMBL1938829)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of PTP1B assessed as para-nitrophenyl phosphate catalyzed hydrolysis of para-nitrophenol by p-NPP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X05PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
M.S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50362191(CHEMBL1938824)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of PTP1B assessed as para-nitrophenyl phosphate catalyzed hydrolysis of para-nitrophenol by p-NPP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X05PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
M.S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50362192(CHEMBL1938825)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of PTP1B assessed as para-nitrophenyl phosphate catalyzed hydrolysis of para-nitrophenol by p-NPP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X05PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
M.S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50362186(CHEMBL1938819)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of PTP1B assessed as para-nitrophenyl phosphate catalyzed hydrolysis of para-nitrophenol by p-NPP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X05PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
M.S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50362197(CHEMBL1938830)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of PTP1B assessed as para-nitrophenyl phosphate catalyzed hydrolysis of para-nitrophenol by p-NPP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X05PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
M.S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50362183(CHEMBL1938816)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of PTP1B assessed as para-nitrophenyl phosphate catalyzed hydrolysis of para-nitrophenol by p-NPP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X05PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
M.S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50362198(CHEMBL1938831)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of PTP1B assessed as para-nitrophenyl phosphate catalyzed hydrolysis of para-nitrophenol by p-NPP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X05PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
M.S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50362193(CHEMBL1938826)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Inhibition of PTP1B assessed as para-nitrophenyl phosphate catalyzed hydrolysis of para-nitrophenol by p-NPP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X05PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
M.S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50362194(CHEMBL1938827)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of PTP1B assessed as para-nitrophenyl phosphate catalyzed hydrolysis of para-nitrophenol by p-NPP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X05PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
M.S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50362185(CHEMBL1938818)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Inhibition of PTP1B assessed as para-nitrophenyl phosphate catalyzed hydrolysis of para-nitrophenol by p-NPP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X05PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
M.S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50171096(CHEMBL371929 | {4-[[3-Bromo-4-(difluoro-phosphono-...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of PTP1B assessed as para-nitrophenyl phosphate catalyzed hydrolysis of para-nitrophenol by p-NPP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X05PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
M.S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50362184(CHEMBL1938817)copy SMILEScopy InChI
Affinity DataIC50: 141nMAssay Description:Inhibition of PTP1B assessed as para-nitrophenyl phosphate catalyzed hydrolysis of para-nitrophenol by p-NPP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X05PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
M.S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50362182(CHEMBL1938815)copy SMILEScopy InChI
Affinity DataIC50: 288nMAssay Description:Inhibition of PTP1B assessed as para-nitrophenyl phosphate catalyzed hydrolysis of para-nitrophenol by p-NPP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X05PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
M.S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50362190(CHEMBL1938823)copy SMILEScopy InChI
Affinity DataIC50: 460nMAssay Description:Inhibition of PTP1B assessed as para-nitrophenyl phosphate catalyzed hydrolysis of para-nitrophenol by p-NPP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X05PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
M.S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50362188(CHEMBL1938821)copy SMILEScopy InChI
Affinity DataIC50: 470nMAssay Description:Inhibition of PTP1B assessed as para-nitrophenyl phosphate catalyzed hydrolysis of para-nitrophenol by p-NPP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X05PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
M.S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50362189(CHEMBL1938822)copy SMILEScopy InChI
Affinity DataIC50: 480nMAssay Description:Inhibition of PTP1B assessed as para-nitrophenyl phosphate catalyzed hydrolysis of para-nitrophenol by p-NPP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X05PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
M.S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50362187(CHEMBL1938820)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of PTP1B assessed as para-nitrophenyl phosphate catalyzed hydrolysis of para-nitrophenol by p-NPP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X05PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
M.S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50362181(({7-[2-(1H-1,2,3-benzotriazol-1-yl)-2-({6-bromo-7-...)copy SMILEScopy InChI
Affinity DataIC50: 580nMAssay Description:Inhibition of TCPTPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X05PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
M.S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50362186(CHEMBL1938819)copy SMILEScopy InChI
Affinity DataIC50: 620nMAssay Description:Inhibition of TCPTPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X05PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
M.S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50171096(CHEMBL371929 | {4-[[3-Bromo-4-(difluoro-phosphono-...)copy SMILEScopy InChI
Affinity DataIC50: 750nMAssay Description:Inhibition of TCPTPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X05PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
M.S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50362195(CHEMBL1938828)copy SMILEScopy InChI
Affinity DataIC50: 870nMAssay Description:Inhibition of TCPTPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X05PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
M.S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50362183(CHEMBL1938816)copy SMILEScopy InChI
Affinity DataIC50: 870nMAssay Description:Inhibition of TCPTPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X05PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
M.S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50362196(CHEMBL1938829)copy SMILEScopy InChI
Affinity DataIC50: 990nMAssay Description:Inhibition of TCPTPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X05PubMed