Compile Data Set for Download or QSAR
Found 24 Enz. Inhib. hit(s) with all data for entry = 50034784
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50283917(1-(1,1-Diphenyl-silolan-3-yl)-4-(4-fluoro-phenyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:In vitro binding affinity towards serotonin 5-HT2A receptor in rat cortical membranes using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1D6M
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50283931(1-(1,1-Diphenyl-silolan-3-yl)-4-phenyl-piperazine ...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:In vitro binding affinity towards serotonin 5-HT2A receptor in rat cortical membranes using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1D6M
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50001775((ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methyle...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:In vitro binding affinity towards serotonin 5-HT2A receptor in rat cortical membranes using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1D6M
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50283920(1-[1,1-Bis-(4-fluoro-phenyl)-silolan-3-yl]-4-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:In vitro binding affinity towards serotonin 5-HT2A receptor in rat cortical membranes using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1D6M
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50283920(1-[1,1-Bis-(4-fluoro-phenyl)-silolan-3-yl]-4-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:In vitro binding affinity towards serotonin 5-HT2A receptor in rat cortical membranes using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1D6M
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50283928(1-(1,1-Diphenyl-silolan-3-yl)-4-(3-fluoro-phenyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 3.40nMAssay Description:In vitro binding affinity towards serotonin 5-HT2A receptor in rat cortical membranes using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1D6M
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50283929(1-(1,1-Diphenyl-silolan-3-yl)-4-p-tolyl-piperazine...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:In vitro binding affinity towards serotonin 5-HT2A receptor in rat cortical membranes using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1D6M
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50283921(1-(1,1-Diphenyl-silolan-3-yl)-4-(4-fluoro-phenyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:In vitro binding affinity towards serotonin 5-HT2A receptor in rat cortical membranes using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1D6M
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50283919(1-[1,1-Bis-(4-fluoro-phenyl)-silolan-3-yl]-4-(4-fl...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:In vitro binding affinity towards serotonin 5-HT2A receptor in rat cortical membranes using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1D6M
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50283924(1-(4-Chloro-phenyl)-4-(1,1-diphenyl-silolan-3-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:In vitro binding affinity towards serotonin 5-HT2A receptor in rat cortical membranes using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1D6M
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50283918(1-[1-(4-Fluoro-phenyl)-1-phenyl-silolan-3-yl]-4-ph...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:In vitro binding affinity towards serotonin 5-HT2A receptor in rat cortical membranes using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1D6M
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50283918(1-[1-(4-Fluoro-phenyl)-1-phenyl-silolan-3-yl]-4-ph...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:In vitro binding affinity towards serotonin 5-HT2A receptor in rat cortical membranes using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1D6M
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50283923(1-(1,1-Diphenyl-silolan-3-yl)-4-pyridin-2-yl-piper...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:In vitro binding affinity towards serotonin 5-HT2A receptor in rat cortical membranes using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1D6M
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50283926(1-(1,1-Diphenyl-silolan-3-yl)-4-m-tolyl-piperazine...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:In vitro binding affinity towards serotonin 5-HT2A receptor in rat cortical membranes using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1D6M
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50283925(4-[4-(1,1-Diphenyl-silolan-3-yl)-piperazin-1-yl]-p...)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:In vitro binding affinity towards serotonin 5-HT2A receptor in rat cortical membranes using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1D6M
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50283927(1-(1,1-Diphenyl-silolan-3-yl)-4-phenyl-piperidine ...)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:In vitro binding affinity towards serotonin 5-HT2A receptor in rat cortical membranes using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1D6M
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50283930(2-[4-(1,1-Diphenyl-silolan-3-yl)-piperazin-1-yl]-p...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:In vitro binding affinity towards serotonin 5-HT2A receptor in rat cortical membranes using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1D6M
TargetD(2) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50283920(1-[1,1-Bis-(4-fluoro-phenyl)-silolan-3-yl]-4-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Binding affinity towards dopamine D2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1D6M
TargetD(2) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50283920(1-[1,1-Bis-(4-fluoro-phenyl)-silolan-3-yl]-4-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Binding affinity towards dopamine D2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1D6M
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50283932(1-(1,1-Diphenyl-silolan-3-yl)-4-(2-fluoro-phenyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:In vitro binding affinity towards serotonin 5-HT2A receptor in rat cortical membranes using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1D6M
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50283920(1-[1,1-Bis-(4-fluoro-phenyl)-silolan-3-yl]-4-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity towards muscarinic receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1D6M
TargetHistamine H1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50283920(1-[1,1-Bis-(4-fluoro-phenyl)-silolan-3-yl]-4-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity towards histamine H1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1D6M
TargetHistamine H1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50283920(1-[1,1-Bis-(4-fluoro-phenyl)-silolan-3-yl]-4-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity towards histamine H1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1D6M
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50283920(1-[1,1-Bis-(4-fluoro-phenyl)-silolan-3-yl]-4-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity towards muscarinic receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1D6M