Compile Data Set for Download or QSAR
Found 27 Enz. Inhib. hit(s) with all data for entry = 50034974
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50035729(8-Methyl-3-p-tolyl-8-aza-bicyclo[3.2.1]octane | 8-...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibitory activity against radioligand [3H]WIN-35428 binding at the dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z162NPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50073433((R)-8-Methyl-2-phenyl-3-p-tolyl-8-aza-bicyclo[3.2....)copy SMILEScopy InChI
Affinity DataIC50: 1.96nMAssay Description:Inhibitory activity against radioligand [3H]WIN-35428 binding at the dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z162NPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50073433((R)-8-Methyl-2-phenyl-3-p-tolyl-8-aza-bicyclo[3.2....)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against radioligand [3H]WIN-35428 binding at the dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z162NPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50073434((R)-8-Methyl-2,3-diphenyl-8-aza-bicyclo[3.2.1]octa...)copy SMILEScopy InChI
Affinity DataIC50: 12.6nMAssay Description:Inhibitory activity against radioligand [3H]WIN-35428 binding at the dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z162NPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50073434((R)-8-Methyl-2,3-diphenyl-8-aza-bicyclo[3.2.1]octa...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibitory activity against radioligand [3H]WIN-35428 binding at the dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z162NPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50366564(CHEMBL1790051 | CHEMBL83729 | WIN-35065-2)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibitory activity against radioligand [3H]WIN-35428 binding at the dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z162NPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50450807(CHEMBL3085511)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibitory activity against radioligand [3H]WIN-35428 binding at the dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z162NPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50450807(CHEMBL3085511)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibitory activity against radioligand [3H]WIN-35428 binding at the dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z162NPubMed
TargetTransporter(Rattus norvegicus)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50035729(8-Methyl-3-p-tolyl-8-aza-bicyclo[3.2.1]octane | 8-...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibitory activity against radioligand [3H]nisoxetine binding at the norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z162NPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM22418(Cocaine | Cocaine (-) | methyl (1R,2R,3S,5S)-3-(be...)copy SMILEScopy InChI
Affinity DataIC50: 89nMAssay Description:Inhibitory activity against radioligand [3H]WIN-35428 binding at the dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z162NPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50035729(8-Methyl-3-p-tolyl-8-aza-bicyclo[3.2.1]octane | 8-...)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Inhibitory activity against radioligand [3H]paroxetine binding at the serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z162NPubMed
TargetTransporter(Rattus norvegicus)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50073433((R)-8-Methyl-2-phenyl-3-p-tolyl-8-aza-bicyclo[3.2....)copy SMILEScopy InChI
Affinity DataIC50: 479nMAssay Description:Inhibitory activity against radioligand [3H]nisoxetine binding at the norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z162NPubMed
TargetTransporter(Rattus norvegicus)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50073433((R)-8-Methyl-2-phenyl-3-p-tolyl-8-aza-bicyclo[3.2....)copy SMILEScopy InChI
Affinity DataIC50: 479nMAssay Description:Inhibitory activity against radioligand [3H]nisoxetine binding at the norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z162NPubMed
TargetTransporter(Rattus norvegicus)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50073434((R)-8-Methyl-2,3-diphenyl-8-aza-bicyclo[3.2.1]octa...)copy SMILEScopy InChI
Affinity DataIC50: 690nMAssay Description:Inhibitory activity against radioligand [3H]nisoxetine binding at the norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z162NPubMed
TargetTransporter(Rattus norvegicus)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50073434((R)-8-Methyl-2,3-diphenyl-8-aza-bicyclo[3.2.1]octa...)copy SMILEScopy InChI
Affinity DataIC50: 917nMAssay Description:Inhibitory activity against radioligand [3H]nisoxetine binding at the norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z162NPubMed
TargetTransporter(Rattus norvegicus)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50366564(CHEMBL1790051 | CHEMBL83729 | WIN-35065-2)copy SMILEScopy InChI
Affinity DataIC50: 920nMAssay Description:Inhibitory activity against radioligand [3H]nisoxetine binding at the norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z162NPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM22418(Cocaine | Cocaine (-) | methyl (1R,2R,3S,5S)-3-(be...)copy SMILEScopy InChI
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibitory activity against radioligand [3H]paroxetine binding at the serotonin transporterMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50366564(CHEMBL1790051 | CHEMBL83729 | WIN-35065-2)copy SMILEScopy InChI
Affinity DataIC50: 1.96E+3nMAssay Description:Inhibitory activity against radioligand [3H]paroxetine binding at the serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z162NPubMed
TargetTransporter(Rattus norvegicus)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50450807(CHEMBL3085511)copy SMILEScopy InChI
Affinity DataIC50: 2.67E+3nMAssay Description:Inhibitory activity against radioligand [3H]nisoxetine binding at the norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z162NPubMed
TargetTransporter(Rattus norvegicus)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50450807(CHEMBL3085511)copy SMILEScopy InChI
Affinity DataIC50: 2.77E+3nMAssay Description:Inhibitory activity against radioligand [3H]nisoxetine binding at the norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z162NPubMed
TargetTransporter(Rattus norvegicus)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM22418(Cocaine | Cocaine (-) | methyl (1R,2R,3S,5S)-3-(be...)copy SMILEScopy InChI
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibitory activity against radioligand [3H]nisoxetine binding at the norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z162NPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50073433((R)-8-Methyl-2-phenyl-3-p-tolyl-8-aza-bicyclo[3.2....)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibitory activity against radioligand [3H]nisoxetine binding at the norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z162NPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50073433((R)-8-Methyl-2-phenyl-3-p-tolyl-8-aza-bicyclo[3.2....)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibitory activity against radioligand [3H]paroxetine binding at the serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z162NPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50073434((R)-8-Methyl-2,3-diphenyl-8-aza-bicyclo[3.2.1]octa...)copy SMILEScopy InChI
Affinity DataIC50: 2.11E+4nMAssay Description:Inhibitory activity against radioligand [3H]paroxetine binding at the serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z162NPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50073434((R)-8-Methyl-2,3-diphenyl-8-aza-bicyclo[3.2.1]octa...)copy SMILEScopy InChI
Affinity DataIC50: 2.11E+4nMAssay Description:Inhibitory activity against radioligand [3H]paroxetine binding at the serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z162NPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50450807(CHEMBL3085511)copy SMILEScopy InChI
Affinity DataIC50: 3.47E+4nMAssay Description:Inhibitory activity against radioligand [3H]paroxetine binding at the serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z162NPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50450807(CHEMBL3085511)copy SMILEScopy InChI
Affinity DataIC50: 3.47E+4nMAssay Description:Inhibitory activity against radioligand [3H]paroxetine binding at the serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z162NPubMed