Compile Data Set for Download or QSAR
Found 28 Enz. Inhib. hit(s) with all data for entry = 50035041
TargetSodium-dependent dopamine transporter(Macaca fascicularis)
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50035730(3-(3,4-Dichloro-phenyl)-8-methyl-8-aza-bicyclo[3.2...)copy SMILEScopy InChI
Affinity DataIC50: 0.380nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine transporter (DAT) of cynomolgus monkey caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5TGQPubMed
TargetSodium-dependent dopamine transporter(Macaca fascicularis)
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50035730(3-(3,4-Dichloro-phenyl)-8-methyl-8-aza-bicyclo[3.2...)copy SMILEScopy InChI
Affinity DataIC50: 0.380nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine transporter (DAT) of cynomolgus monkey caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5TGQPubMed
TargetSodium-dependent dopamine transporter(Macaca fascicularis)
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50046734(3-(3,4-Dichloro-phenyl)-8-aza-bicyclo[3.2.1]octane...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine transporter (DAT) of cynomolgus monkey caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5TGQPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50046734(3-(3,4-Dichloro-phenyl)-8-aza-bicyclo[3.2.1]octane...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibition of [3H]citalopram binding to serotonin transporter (SERT) of cynomolgus monkey caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5TGQPubMed
TargetSodium-dependent dopamine transporter(Macaca fascicularis)
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50076050(3-(3,4-Dichloro-phenyl)-8-methyl-8-aza-bicyclo[3.2...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine transporter (DAT) of cynomolgus monkey caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5TGQPubMed
TargetSodium-dependent dopamine transporter(Macaca fascicularis)
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50059480(3-(3,4-Dichloro-phenyl)-8-oxa-bicyclo[3.2.1]octane...)copy SMILEScopy InChI
Affinity DataIC50: 3.10nMAssay Description:Inhibition of [3H]citalopram binding to serotonin transporter (SERT) of cynomolgus monkey caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5TGQPubMed
TargetSodium-dependent dopamine transporter(Macaca fascicularis)
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50059480(3-(3,4-Dichloro-phenyl)-8-oxa-bicyclo[3.2.1]octane...)copy SMILEScopy InChI
Affinity DataIC50: 3.10nMAssay Description:Inhibition of [3H]citalopram binding to serotonin transporter (SERT) of cynomolgus monkey caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5TGQPubMed
TargetSodium-dependent dopamine transporter(Macaca fascicularis)
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50059480(3-(3,4-Dichloro-phenyl)-8-oxa-bicyclo[3.2.1]octane...)copy SMILEScopy InChI
Affinity DataIC50: 3.40nMAssay Description:Inhibition of [3H]citalopram binding to serotonin transporter (SERT) of cynomolgus monkey caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5TGQPubMed
TargetSodium-dependent dopamine transporter(Macaca fascicularis)
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50059480(3-(3,4-Dichloro-phenyl)-8-oxa-bicyclo[3.2.1]octane...)copy SMILEScopy InChI
Affinity DataIC50: 3.40nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine transporter (DAT) of cynomolgus monkey caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5TGQPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50059480(3-(3,4-Dichloro-phenyl)-8-oxa-bicyclo[3.2.1]octane...)copy SMILEScopy InChI
Affinity DataIC50: 4.70nMAssay Description:Inhibition of [3H]citalopram binding to serotonin transporter (SERT) of cynomolgus monkey caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5TGQPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50059480(3-(3,4-Dichloro-phenyl)-8-oxa-bicyclo[3.2.1]octane...)copy SMILEScopy InChI
Affinity DataIC50: 6.5nMAssay Description:Inhibition of [3H]citalopram binding to serotonin transporter (SERT) of cynomolgus monkey caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5TGQPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50059480(3-(3,4-Dichloro-phenyl)-8-oxa-bicyclo[3.2.1]octane...)copy SMILEScopy InChI
Affinity DataIC50: 6.5nMAssay Description:Inhibition of [3H]citalopram binding to serotonin transporter (SERT) of cynomolgus monkey caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5TGQPubMed
TargetSodium-dependent dopamine transporter(Macaca fascicularis)
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50076048((1R/1S)-methyl 3-(3,4-dichlorophenyl)bicyclo[3.2.1...)copy SMILEScopy InChI
Affinity DataIC50: 7.10nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine transporter (DAT) of cynomolgus monkey caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5TGQPubMed
TargetSodium-dependent dopamine transporter(Macaca fascicularis)
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50076049(3-(3,4-Dichloro-phenyl)-bicyclo[3.2.1]octane-2-car...)copy SMILEScopy InChI
Affinity DataIC50: 9.60nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine transporter (DAT) of cynomolgus monkey caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5TGQPubMed
TargetSodium-dependent dopamine transporter(Macaca fascicularis)
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50076049(3-(3,4-Dichloro-phenyl)-bicyclo[3.2.1]octane-2-car...)copy SMILEScopy InChI
Affinity DataIC50: 9.60nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine transporter (DAT) of cynomolgus monkey caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5TGQPubMed
TargetSodium-dependent dopamine transporter(Macaca fascicularis)
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50076047((1R/1S)-methyl 3-(3,4-dichlorophenyl)-8-oxa-bicycl...)copy SMILEScopy InChI
Affinity DataIC50: 12.8nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine transporter (DAT) of cynomolgus monkey caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5TGQPubMed
TargetSodium-dependent dopamine transporter(Macaca fascicularis)
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50076047((1R/1S)-methyl 3-(3,4-dichlorophenyl)-8-oxa-bicycl...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine transporter (DAT) of cynomolgus monkey caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5TGQPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50035730(3-(3,4-Dichloro-phenyl)-8-methyl-8-aza-bicyclo[3.2...)copy SMILEScopy InChI
Affinity DataIC50: 27.6nMAssay Description:Inhibition of [3H]citalopram binding to serotonin transporter (SERT) of cynomolgus monkey caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5TGQPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50035730(3-(3,4-Dichloro-phenyl)-8-methyl-8-aza-bicyclo[3.2...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine transporter (DAT) of cynomolgus monkey caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5TGQPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50076049(3-(3,4-Dichloro-phenyl)-bicyclo[3.2.1]octane-2-car...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of [3H]citalopram binding to serotonin transporter (SERT) of cynomolgus monkey caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5TGQPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50076049(3-(3,4-Dichloro-phenyl)-bicyclo[3.2.1]octane-2-car...)copy SMILEScopy InChI
Affinity DataIC50: 33.4nMAssay Description:Inhibition of [3H]citalopram binding to serotonin transporter (SERT) of cynomolgus monkey caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5TGQPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50059480(3-(3,4-Dichloro-phenyl)-8-oxa-bicyclo[3.2.1]octane...)copy SMILEScopy InChI
Affinity DataIC50: 64.5nMAssay Description:Inhibition of [3H]citalopram binding to serotonin transporter (SERT) of cynomolgus monkey caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5TGQPubMed
TargetSodium-dependent dopamine transporter(Macaca fascicularis)
Organix Inc

Curated by ChEMBL
LigandPNGBDBM22418(Cocaine | Cocaine (-) | methyl (1R,2R,3S,5S)-3-(be...)copy SMILEScopy InChI
Affinity DataIC50: 96nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine transporter (DAT) of cynomolgus monkey caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5TGQPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix Inc

Curated by ChEMBL
LigandPNGBDBM22418(Cocaine | Cocaine (-) | methyl (1R,2R,3S,5S)-3-(be...)copy SMILEScopy InChI
Affinity DataIC50: 270nMAssay Description:Inhibition of [3H]citalopram binding to serotonin transporter (SERT) of cynomolgus monkey caudate-putamenMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50076050(3-(3,4-Dichloro-phenyl)-8-methyl-8-aza-bicyclo[3.2...)copy SMILEScopy InChI
Affinity DataIC50: 867nMAssay Description:Inhibition of [3H]citalopram binding to serotonin transporter (SERT) of cynomolgus monkey caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5TGQPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50076047((1R/1S)-methyl 3-(3,4-dichlorophenyl)-8-oxa-bicycl...)copy SMILEScopy InChI
Affinity DataIC50: 1.96E+3nMAssay Description:Inhibition of [3H]citalopram binding to serotonin transporter (SERT) of cynomolgus monkey caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5TGQPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50076047((1R/1S)-methyl 3-(3,4-dichlorophenyl)-8-oxa-bicycl...)copy SMILEScopy InChI
Affinity DataIC50: 2.12E+3nMAssay Description:Inhibition of [3H]citalopram binding to serotonin transporter (SERT) of cynomolgus monkey caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5TGQPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50076048((1R/1S)-methyl 3-(3,4-dichlorophenyl)bicyclo[3.2.1...)copy SMILEScopy InChI
Affinity DataIC50: 5.16E+3nMAssay Description:Inhibition of [3H]citalopram binding to serotonin transporter (SERT) of cynomolgus monkey caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5TGQPubMed