Compile Data Set for Download or QSAR
Found 20 Enz. Inhib. hit(s) with all data for entry = 50035174
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University of Toledo

Curated by ChEMBL
LigandPNGBDBM50070942((-)-Epigallocatechin gallate | (-)-Epigallocatechi...)copy SMILEScopy InChI
Affinity DataIC50: 730nMAssay Description:Inhibition of polymerization in wild type HIV-1 RT with poly rC/dG12-18 template primer and [3H]dGTPMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92BTRPubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University of Toledo

Curated by ChEMBL
LigandPNGBDBM50153015((-)-Epicatechin-3-gallate | (-)-epicatechin 3-O-ga...)copy SMILEScopy InChI
Affinity DataIC50: 760nMAssay Description:Inhibition of polymerization in wild type HIV-1 RT with poly rC/dG12-18 template primer and [3H]dGTPMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92BTRPubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Toledo

Curated by ChEMBL
LigandPNGBDBM50105589(2,3,4-Trihydroxy-benzoic acid 5,7-dihydroxy-chroma...)copy SMILEScopy InChI
Affinity DataIC50: 2.36E+3nMAssay Description:Inhibitory concentration against polymerization in A17 double mutant HIV-1 RT using a template primer of poly rC/dG12-18 and [3H]dGTPMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92BTRPubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University of Toledo

Curated by ChEMBL
LigandPNGBDBM50105589(2,3,4-Trihydroxy-benzoic acid 5,7-dihydroxy-chroma...)copy SMILEScopy InChI
Affinity DataIC50: 3.83E+3nMAssay Description:Inhibition of polymerization in wild type HIV-1 RT with poly rC/dG12-18 template primer and [3H]dGTPMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92BTRPubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Toledo

Curated by ChEMBL
LigandPNGBDBM50105592(2,3,4-Trihydroxy-benzoic acid 2-(6,7-dihydroxy-chr...)copy SMILEScopy InChI
Affinity DataIC50: 6.33E+3nMAssay Description:Inhibitory concentration against polymerization in A17 double mutant HIV-1 RT using a template primer of poly rC/dG12-18 and [3H]dGTPMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92BTRPubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University of Toledo

Curated by ChEMBL
LigandPNGBDBM50105592(2,3,4-Trihydroxy-benzoic acid 2-(6,7-dihydroxy-chr...)copy SMILEScopy InChI
Affinity DataIC50: 1.07E+4nMAssay Description:Inhibition of polymerization in wild type HIV-1 RT with poly rC/dG12-18 template primer and [3H]dGTPMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92BTRPubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Toledo

Curated by ChEMBL
LigandPNGBDBM50105585(2,3,4-Trihydroxy-benzoic acid 7-hydroxy-chroman-3-...)copy SMILEScopy InChI
Affinity DataIC50: 3.08E+4nMAssay Description:Inhibitory concentration against polymerization in A17 double mutant HIV-1 RT using a template primer of poly rC/dG12-18 and [3H]dGTPMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92BTRPubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University of Toledo

Curated by ChEMBL
LigandPNGBDBM50105585(2,3,4-Trihydroxy-benzoic acid 7-hydroxy-chroman-3-...)copy SMILEScopy InChI
Affinity DataIC50: 3.63E+4nMAssay Description:Inhibition of polymerization in wild type HIV-1 RT with poly rC/dG12-18 template primer and [3H]dGTPMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92BTRPubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University of Toledo

Curated by ChEMBL
LigandPNGBDBM50105590(2,3-Dihydroxy-benzoic acid 5,7-dihydroxy-chroman-3...)copy SMILEScopy InChI
Affinity DataIC50: 3.72E+4nMAssay Description:Inhibition of polymerization in wild type HIV-1 RT with poly rC/dG12-18 template primer and [3H]dGTPMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92BTRPubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University of Toledo

Curated by ChEMBL
LigandPNGBDBM50105586(2,3,4-Trihydroxy-benzoic acid 5-hydroxy-chroman-3-...)copy SMILEScopy InChI
Affinity DataIC50: 4.55E+4nMAssay Description:Inhibition of polymerization in wild type HIV-1 RT with poly rC/dG12-18 template primer and [3H]dGTPMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92BTRPubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Toledo

Curated by ChEMBL
LigandPNGBDBM50105586(2,3,4-Trihydroxy-benzoic acid 5-hydroxy-chroman-3-...)copy SMILEScopy InChI
Affinity DataIC50: 6.47E+4nMAssay Description:Inhibitory concentration against polymerization in A17 double mutant HIV-1 RT using a template primer of poly rC/dG12-18 and [3H]dGTPMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92BTRPubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University of Toledo

Curated by ChEMBL
LigandPNGBDBM50105593(2,4-Dihydroxy-benzoic acid 5,7-dihydroxy-chroman-3...)copy SMILEScopy InChI
Affinity DataIC50: 9.63E+4nMAssay Description:Inhibition of polymerization in wild type HIV-1 RT with poly rC/dG12-18 template primer and [3H]dGTPMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92BTRPubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University of Toledo

Curated by ChEMBL
LigandPNGBDBM50105587(Benzoic acid 5,7-dihydroxy-chroman-3-yl ester | CH...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of polymerization in wild type HIV-1 RT with poly rC/dG12-18 template primer and [3H]dGTPMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92BTRPubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Toledo

Curated by ChEMBL
LigandPNGBDBM50105588(2,3,4-Trihydroxy-benzoic acid chroman-3-yl ester |...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration against polymerization in A17 double mutant HIV-1 RT using a template primer of poly rC/dG12-18 and [3H]dGTPMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92BTRPubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University of Toledo

Curated by ChEMBL
LigandPNGBDBM50105588(2,3,4-Trihydroxy-benzoic acid chroman-3-yl ester |...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of polymerization in wild type HIV-1 RT with poly rC/dG12-18 template primer and [3H]dGTPMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92BTRPubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Toledo

Curated by ChEMBL
LigandPNGBDBM50105587(Benzoic acid 5,7-dihydroxy-chroman-3-yl ester | CH...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration against polymerization in A17 double mutant HIV-1 RT using a template primer of poly rC/dG12-18 and [3H]dGTPMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92BTRPubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University of Toledo

Curated by ChEMBL
LigandPNGBDBM50105584(3-Hydroxy-benzoic acid 5,7-dihydroxy-chroman-3-yl ...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of polymerization in wild type HIV-1 RT with poly rC/dG12-18 template primer and [3H]dGTPMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92BTRPubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Toledo

Curated by ChEMBL
LigandPNGBDBM50105590(2,3-Dihydroxy-benzoic acid 5,7-dihydroxy-chroman-3...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration against polymerization in A17 double mutant HIV-1 RT using a template primer of poly rC/dG12-18 and [3H]dGTPMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92BTRPubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University of Toledo

Curated by ChEMBL
LigandPNGBDBM50085536(3,4,5-Trihydroxybenzoate, X | 3,4,5-trihydroxybenz...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of polymerization in wild type HIV-1 RT with poly rC/dG12-18 template primer and [3H]dGTPMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92BTRPubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University of Toledo

Curated by ChEMBL
LigandPNGBDBM23417(α-CA inhibitor, 4 | (-)-Epicatechin | (2R,3R)...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of polymerization in wild type HIV-1 RT with poly rC/dG12-18 template primer and [3H]dGTPMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92BTRPubMed