Compile Data Set for Download or QSAR
Found 36 Enz. Inhib. hit(s) with all data for entry = 50035305
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50035738((R)-3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2...)copy SMILEScopy InChI
Affinity DataKi:  1.10nMAssay Description:Compound was tested for inhibition of [125I]RTI-55 binding to dopamine transporter in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DN45K3PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50129369(3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]o...)copy SMILEScopy InChI
Affinity DataKi:  6.70nMAssay Description:Compound was tested for inhibition of [125I]RTI-55 binding to dopamine transporter in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DN45K3PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50129369(3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]o...)copy SMILEScopy InChI
Affinity DataKi:  7.90nMAssay Description:Compound was tested for inhibition of [125I]RTI-55 binding to Serotonin transporter in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DN45K3PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50129371(3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]o...)copy SMILEScopy InChI
Affinity DataKi:  18nMAssay Description:Compound was tested for inhibition of [125I]RTI-55 binding to dopamine transporter in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DN45K3PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50129370(3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]o...)copy SMILEScopy InChI
Affinity DataKi:  22nMAssay Description:Compound was tested for inhibition of [125I]RTI-55 binding to dopamine transporter in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DN45K3PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50035738((R)-3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2...)copy SMILEScopy InChI
Affinity DataKi:  37nMAssay Description:Compound was tested for inhibition of [125I]RTI-55 binding to dopamine transporter in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DN45K3PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50035738((R)-3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2...)copy SMILEScopy InChI
Affinity DataKi:  45nMAssay Description:Compound was tested for inhibition of [125I]RTI-55 binding to Serotonin transporter in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DN45K3PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50129368(3-(4-Chloro-phenyl)--8-methyl-8-aza-bicyclo[3.2.1]...)copy SMILEScopy InChI
Affinity DataKi:  65nMAssay Description:Compound was tested for inhibition of [125I]RTI-55 binding to Serotonin transporter in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DN45K3PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50129371(3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]o...)copy SMILEScopy InChI
Affinity DataKi:  102nMAssay Description:Compound was tested for inhibition of [125I]RTI-55 binding to Serotonin transporter in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DN45K3PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM22418(Cocaine | Cocaine (-) | methyl (1R,2R,3S,5S)-3-(be...)copy SMILEScopy InChI
Affinity DataKi:  272nMAssay Description:Compound was tested for inhibition of [125I]RTI-55 binding to Serotonin transporter in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DN45K3PubMedDrugBank
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50129371(3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]o...)copy SMILEScopy InChI
Affinity DataKi:  330nMAssay Description:Compound was tested for inhibition of [125I]-RTI-55 binding to norepinephrine transporter HEK cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DN45K3PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50129368(3-(4-Chloro-phenyl)--8-methyl-8-aza-bicyclo[3.2.1]...)copy SMILEScopy InChI
Affinity DataKi:  357nMAssay Description:Compound was tested for inhibition of [125I]RTI-55 binding to Serotonin transporter in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DN45K3PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM22418(Cocaine | Cocaine (-) | methyl (1R,2R,3S,5S)-3-(be...)copy SMILEScopy InChI
Affinity DataKi:  601nMAssay Description:Compound was tested for inhibition of [3H]DA binding to Dopamine transporter in HEK cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50129369(3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]o...)copy SMILEScopy InChI
Affinity DataKi:  830nMAssay Description:Compound was tested for inhibition of [125I]-RTI-55 binding to norepinephrine transporter HEK cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DN45K3PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM22418(Cocaine | Cocaine (-) | methyl (1R,2R,3S,5S)-3-(be...)copy SMILEScopy InChI
Affinity DataKi:  830nMAssay Description:Compound was tested for inhibition of [3H]5-HT binding to Serotonin transporter in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DN45K3PubMedDrugBank
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50129370(3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]o...)copy SMILEScopy InChI
Affinity DataKi:  2.07E+3nMAssay Description:Compound was tested for inhibition of [125I]-RTI-55 binding to norepinephrine transporter HEK cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DN45K3PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50129368(3-(4-Chloro-phenyl)--8-methyl-8-aza-bicyclo[3.2.1]...)copy SMILEScopy InChI
Affinity DataKi:  2.97E+3nMAssay Description:Compound was tested for inhibition of [125I]-RTI-55 binding to norepinephrine transporter HEK cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DN45K3PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50129370(3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]o...)copy SMILEScopy InChI
Affinity DataKi:  3.14E+3nMAssay Description:Compound was tested for inhibition of [125I]RTI-55 binding to Serotonin transporter in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DN45K3PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50035738((R)-3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Compound was tested for inhibition of [3H]NE binding to norepinephrine transporter HEK cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DN45K3PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50035738((R)-3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2...)copy SMILEScopy InChI
Affinity DataIC50: 8.20nMAssay Description:Compound was tested for inhibition of [3H]NE binding to norepinephrine transporter HEK cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DN45K3PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50035738((R)-3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Compound was tested for inhibition of [125I]RTI-55 binding to Serotonin transporter in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DN45K3PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50129368(3-(4-Chloro-phenyl)--8-methyl-8-aza-bicyclo[3.2.1]...)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Compound was tested for inhibition of [3H]DA binding to dopamine (DAT) transporter in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DN45K3PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50129369(3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]o...)copy SMILEScopy InChI
Affinity DataIC50: 99nMAssay Description:Compound was tested for inhibition of [3H]5-HT binding to Serotonin transporter in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DN45K3PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50129370(3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]o...)copy SMILEScopy InChI
Affinity DataIC50: 176nMAssay Description:Compound was tested for inhibition of [125I]-RTI-55 binding to norepinephrine transporter HEK cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DN45K3PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50129371(3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]o...)copy SMILEScopy InChI
Affinity DataIC50: 225nMAssay Description:Compound was tested for inhibition of [3H]5-HT binding to Serotonin transporter in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DN45K3PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50129368(3-(4-Chloro-phenyl)--8-methyl-8-aza-bicyclo[3.2.1]...)copy SMILEScopy InChI
Affinity DataIC50: 266nMAssay Description:Compound was tested for inhibition of [3H]NE binding to norepinephrine transporter HEK cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DN45K3PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM22418(Cocaine | Cocaine (-) | methyl (1R,2R,3S,5S)-3-(be...)copy SMILEScopy InChI
Affinity DataIC50: 267nMAssay Description:Compound was tested for inhibition of [125I]-RTI-55 binding to norepinephrine transporter HEK cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DN45K3PubMedDrugBank
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM22418(Cocaine | Cocaine (-) | methyl (1R,2R,3S,5S)-3-(be...)copy SMILEScopy InChI
Affinity DataIC50: 318nMAssay Description:Compound was tested for inhibition of [125I]-RTI-55 binding to norepinephrine transporter HEK cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM22418(Cocaine | Cocaine (-) | methyl (1R,2R,3S,5S)-3-(be...)copy SMILEScopy InChI
Affinity DataIC50: 385nMAssay Description:Compound was tested for inhibition of [125I]-RTI-55 binding to norepinephrine transporter HEK cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DN45K3PubMedDrugBank
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50129368(3-(4-Chloro-phenyl)--8-methyl-8-aza-bicyclo[3.2.1]...)copy SMILEScopy InChI
Affinity DataIC50: 441nMAssay Description:Compound was tested for inhibition of [3H]5-HT binding to Serotonin transporter in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DN45K3PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50129369(3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]o...)copy SMILEScopy InChI
Affinity DataIC50: 487nMAssay Description:Compound was tested for inhibition of [3H]NE binding to norepinephrine transporter HEK cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DN45K3PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50129369(3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]o...)copy SMILEScopy InChI
Affinity DataIC50: 871nMAssay Description:Compound was tested for inhibition of [3H]DA binding to dopamine (DAT) transporter in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DN45K3PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50129371(3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]o...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Compound was tested for inhibition of [3H]DA binding to dopamine (DAT) transporter in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DN45K3PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50129370(3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]o...)copy SMILEScopy InChI
Affinity DataIC50: 1.67E+3nMAssay Description:Compound was tested for inhibition of [3H]DA binding to dopamine (DAT) transporter in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DN45K3PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50129371(3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]o...)copy SMILEScopy InChI
Affinity DataIC50: 1.85E+3nMAssay Description:Compound was tested for inhibition of [3H]NE binding to norepinephrine transporter HEK cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DN45K3PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50129370(3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]o...)copy SMILEScopy InChI
Affinity DataIC50: 2.26E+3nMAssay Description:Compound was tested for inhibition of [3H]NE binding to norepinephrine transporter HEK cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DN45K3PubMed