Compile Data Set for Download or QSAR
Found 27 Enz. Inhib. hit(s) with all data for entry = 50035372
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM22165(1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of binding of [3H]WIN-35 428 to (DAT) dopamine transporter in rat striatumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J38T3XPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50098392((2,2-Diphenyl-ethyl)-[1-(4-fluoro-benzyl)-piperidi...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of binding of [3H]WIN-35 428 to (DAT) dopamine transporter in rat striatumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J38T3XPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50103818((6-Benzhydryl-piperidin-3-yl)-(4-fluoro-benzyl)-am...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of binding of [3H]WIN-35 428 to (DAT) dopamine transporter in rat striatumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J38T3XPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50127373((6-Benzhydryl-tetrahydro-pyran-3-yl)-(4-nitro-benz...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of binding of [3H]WIN-35 428 to (DAT) dopamine transporter in rat striatumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J38T3XPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50127372(4-[(6-Benzhydryl-tetrahydro-pyran-3-ylamino)-methy...)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:Inhibition of binding of [3H]WIN-35 428 to (DAT) dopamine transporter in rat striatumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J38T3XPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50127371((6-Benzhydryl-tetrahydro-pyran-3-yl)-(4-methoxy-be...)copy SMILEScopy InChI
Affinity DataIC50: 84nMAssay Description:Inhibition of binding of [3H]WIN-35 428 to (DAT) dopamine transporter in rat striatumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J38T3XPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM22165(1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 132nMAssay Description:Inhibition of binding of [3H]citalopram to (SERT) serotonin transporter in rat striatumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J38T3XPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50098392((2,2-Diphenyl-ethyl)-[1-(4-fluoro-benzyl)-piperidi...)copy SMILEScopy InChI
Affinity DataIC50: 137nMAssay Description:Inhibition of binding of [3H]citalopram to (SERT) serotonin transporter in rat striatumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J38T3XPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50127374((6-Benzhydryl-tetrahydro-pyran-3-yl)-(4-fluoro-ben...)copy SMILEScopy InChI
Affinity DataIC50: 163nMAssay Description:Inhibition of binding of [3H]WIN-35 428 to (DAT) dopamine transporter in rat striatumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J38T3XPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50127374((6-Benzhydryl-tetrahydro-pyran-3-yl)-(4-fluoro-ben...)copy SMILEScopy InChI
Affinity DataIC50: 163nMAssay Description:Inhibition of binding of [3H]WIN-35 428 to (DAT) dopamine transporter in rat striatumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J38T3XPubMed
TargetTransporter(Rattus norvegicus)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50127374((6-Benzhydryl-tetrahydro-pyran-3-yl)-(4-fluoro-ben...)copy SMILEScopy InChI
Affinity DataIC50: 232nMAssay Description:Inhibition of binding of [3H]nisoxetine to (NET) norepinephrine transporter in rat striatumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J38T3XPubMed
TargetTransporter(Rattus norvegicus)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50127374((6-Benzhydryl-tetrahydro-pyran-3-yl)-(4-fluoro-ben...)copy SMILEScopy InChI
Affinity DataIC50: 232nMAssay Description:Inhibition of binding of [3H]nisoxetine to (NET) norepinephrine transporter in rat striatumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J38T3XPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM22418(Cocaine | Cocaine (-) | methyl (1R,2R,3S,5S)-3-(be...)copy SMILEScopy InChI
Affinity DataIC50: 266nMAssay Description:Inhibition of binding of [3H]WIN-35 428 to (DAT) dopamine transporter in rat striatumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J38T3XPubMed
TargetTransporter(Rattus norvegicus)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM22165(1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 496nMAssay Description:Inhibition of binding of [3H]nisoxetine to (NET) norepinephrine transporter in rat striatumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J38T3XPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM22418(Cocaine | Cocaine (-) | methyl (1R,2R,3S,5S)-3-(be...)copy SMILEScopy InChI
Affinity DataIC50: 737nMAssay Description:Inhibition of binding of [3H]citalopram to (SERT) serotonin transporter in rat striatumMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50127373((6-Benzhydryl-tetrahydro-pyran-3-yl)-(4-nitro-benz...)copy SMILEScopy InChI
Affinity DataIC50: 738nMAssay Description:Inhibition of binding of [3H]citalopram to (SERT) serotonin transporter in rat striatumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J38T3XPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50127372(4-[(6-Benzhydryl-tetrahydro-pyran-3-ylamino)-methy...)copy SMILEScopy InChI
Affinity DataIC50: 863nMAssay Description:Inhibition of binding of [3H]citalopram to (SERT) serotonin transporter in rat striatumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J38T3XPubMed
TargetTransporter(Rattus norvegicus)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50127373((6-Benzhydryl-tetrahydro-pyran-3-yl)-(4-nitro-benz...)copy SMILEScopy InChI
Affinity DataIC50: 968nMAssay Description:Inhibition of binding of [3H]nisoxetine to (NET) norepinephrine transporter in rat striatumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J38T3XPubMed
TargetTransporter(Rattus norvegicus)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50103818((6-Benzhydryl-piperidin-3-yl)-(4-fluoro-benzyl)-am...)copy SMILEScopy InChI
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of binding of [3H]nisoxetine to (NET) norepinephrine transporter in rat striatumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J38T3XPubMed
TargetTransporter(Rattus norvegicus)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50098392((2,2-Diphenyl-ethyl)-[1-(4-fluoro-benzyl)-piperidi...)copy SMILEScopy InChI
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of binding of [3H]nisoxetine to (NET) norepinephrine transporter in rat striatumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J38T3XPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50127371((6-Benzhydryl-tetrahydro-pyran-3-yl)-(4-methoxy-be...)copy SMILEScopy InChI
Affinity DataIC50: 1.18E+3nMAssay Description:Inhibition of binding of [3H]citalopram to (SERT) serotonin transporter in rat striatumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J38T3XPubMed
TargetTransporter(Rattus norvegicus)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50127371((6-Benzhydryl-tetrahydro-pyran-3-yl)-(4-methoxy-be...)copy SMILEScopy InChI
Affinity DataIC50: 1.55E+3nMAssay Description:Inhibition of binding of [3H]nisoxetine to (NET) norepinephrine transporter in rat striatumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J38T3XPubMed
TargetTransporter(Rattus norvegicus)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50127372(4-[(6-Benzhydryl-tetrahydro-pyran-3-ylamino)-methy...)copy SMILEScopy InChI
Affinity DataIC50: 1.58E+3nMAssay Description:Inhibition of binding of [3H]nisoxetine to (NET) norepinephrine transporter in rat striatumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J38T3XPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50127374((6-Benzhydryl-tetrahydro-pyran-3-yl)-(4-fluoro-ben...)copy SMILEScopy InChI
Affinity DataIC50: 1.86E+3nMAssay Description:Inhibition of binding of [3H]citalopram to (SERT) serotonin transporter in rat striatumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J38T3XPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50127374((6-Benzhydryl-tetrahydro-pyran-3-yl)-(4-fluoro-ben...)copy SMILEScopy InChI
Affinity DataIC50: 1.86E+3nMAssay Description:Inhibition of binding of [3H]citalopram to (SERT) serotonin transporter in rat striatumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J38T3XPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50103818((6-Benzhydryl-piperidin-3-yl)-(4-fluoro-benzyl)-am...)copy SMILEScopy InChI
Affinity DataIC50: 2.22E+3nMAssay Description:Inhibition of binding of [3H]citalopram to (SERT) serotonin transporter in rat striatumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J38T3XPubMed
TargetTransporter(Rattus norvegicus)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM22418(Cocaine | Cocaine (-) | methyl (1R,2R,3S,5S)-3-(be...)copy SMILEScopy InChI
Affinity DataIC50: 3.53E+3nMAssay Description:Inhibition of binding of [3H]nisoxetine to (NET) norepinephrine transporter in rat striatumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J38T3XPubMed