Compile Data Set for Download or QSAR
Found 34 Enz. Inhib. hit(s) with all data for entry = 50035401
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM31090((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4505PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122578(4-Dimethylamino-but-2-ynoic acid [4-(3-bromo-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4505PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122565(4-Dipropylamino-but-2-ynoic acid [4-(3-bromo-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4505PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50148236(4-(2-Methoxymethyl-pyrrolidin-1-yl)-but-2-ynoic ac...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4505PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122566(4-Diisopropylamino-but-2-ynoic acid [4-(3-bromo-ph...)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4505PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122567((E)-4-Dimethylamino-but-2-enoic acid [4-(3-bromo-p...)copy SMILEScopy InChI
Affinity DataIC50: 310nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4505PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50148234(3-Methoxymethoxy-propynoic acid [4-(3-bromo-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 330nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4505PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122577(4-Thiomorpholin-4-yl-but-2-ynoic acid [4-(3-bromo-...)copy SMILEScopy InChI
Affinity DataIC50: 550nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4505PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122579(CHEMBL117326 | N-[4-(3-Chloro-4-fluoro-phenylamino...)copy SMILEScopy InChI
Affinity DataIC50: 560nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4505PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122562(CHEMBL281300 | N-[4-(3-Bromo-phenylamino)-3-cyano-...)copy SMILEScopy InChI
Affinity DataIC50: 590nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4505PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122563((E)-4-Dimethylamino-but-2-enoic acid [4-(3-chloro-...)copy SMILEScopy InChI
Affinity DataIC50: 650nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4505PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122588(4-Methoxy-but-2-ynoic acid [4-(3-bromo-phenylamino...)copy SMILEScopy InChI
Affinity DataIC50: 790nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4505PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122560((E)-4-Dimethylamino-but-2-enoic acid [4-(3-bromo-p...)copy SMILEScopy InChI
Affinity DataIC50: 790nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4505PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122583(CHEMBL324718 | N-[4-(3-Bromo-phenylamino)-3-cyano-...)copy SMILEScopy InChI
Affinity DataIC50: 810nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4505PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122572(But-2-ynoic acid [4-(3-bromo-phenylamino)-3-cyano-...)copy SMILEScopy InChI
Affinity DataIC50: 910nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4505PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50148235(3-(2-Methoxy-ethoxy)-propynoic acid [4-(3-bromo-ph...)copy SMILEScopy InChI
Affinity DataIC50: 930nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4505PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122573(But-2-ynoic acid [4-(3-bromo-phenylamino)-3-cyano-...)copy SMILEScopy InChI
Affinity DataIC50: 940nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4505PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122582(4-Methoxy-but-2-ynoic acid [4-(3-bromo-phenylamino...)copy SMILEScopy InChI
Affinity DataIC50: 960nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4505PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122581((E)-4-Dimethylamino-but-2-enoic acid [4-(3-bromo-p...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4505PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122571((E)-But-2-enoic acid [4-(3-bromo-phenylamino)-3-cy...)copy SMILEScopy InChI
Affinity DataIC50: 1.62E+3nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4505PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122589((E)-4-Diethylamino-but-2-enoic acid [4-(3-chloro-4...)copy SMILEScopy InChI
Affinity DataIC50: 1.91E+3nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4505PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122564((E)-4-Morpholin-4-yl-but-2-enoic acid [4-(3-chloro...)copy SMILEScopy InChI
Affinity DataIC50: 2.29E+3nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4505PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122574((E)-4-Dimethylamino-but-2-enoic acid [4-(3-chloro-...)copy SMILEScopy InChI
Affinity DataIC50: 2.32E+3nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4505PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122568((E)-4-Dimethylamino-but-2-enoic acid [4-(3-chloro-...)copy SMILEScopy InChI
Affinity DataIC50: 2.64E+3nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4505PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122580(CHEMBL114392 | N-[4-(3-Chloro-4-fluoro-phenylamino...)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+3nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4505PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122561((E)-4-Dimethylamino-but-2-enoic acid [4-(3-bromo-p...)copy SMILEScopy InChI
Affinity DataIC50: 2.88E+3nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4505PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122576((E)-4-Morpholin-4-yl-but-2-enoic acid [4-(3-bromo-...)copy SMILEScopy InChI
Affinity DataIC50: 3.83E+3nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4505PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122558((E)-4-Diethylamino-pent-2-enoic acid [4-(3-chloro-...)copy SMILEScopy InChI
Affinity DataIC50: 4.84E+3nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4505PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122587((E)-4-Dimethylamino-pent-2-enoic acid [4-(3-chloro...)copy SMILEScopy InChI
Affinity DataIC50: 5.22E+3nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4505PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122559((E)-4-Morpholin-4-yl-but-2-enoic acid [4-(3-bromo-...)copy SMILEScopy InChI
Affinity DataIC50: 5.39E+3nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4505PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122586((E)-But-2-enoic acid [4-(3-chloro-4-fluoro-phenyla...)copy SMILEScopy InChI
Affinity DataIC50: 7.50E+3nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4505PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122584((E)-4-Morpholin-4-yl-but-2-enoic acid [4-(3-bromo-...)copy SMILEScopy InChI
Affinity DataIC50: 1.03E+4nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4505PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122557((E)-4-Morpholin-4-yl-pent-2-enoic acid [4-(3-chlor...)copy SMILEScopy InChI
Affinity DataIC50: 1.06E+4nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4505PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122585((E)-4-Morpholin-4-yl-but-2-enoic acid [4-(3-chloro...)copy SMILEScopy InChI
Affinity DataIC50: 1.36E+4nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4505PubMed