Compile Data Set for Download or QSAR
Found 40 Enz. Inhib. hit(s) with all data for entry = 50036032
TargetPlatelet-activating factor receptor(Cavia porcellus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50004622(4-(2-Chloro-phenyl)-2-methyl-6-[4-(2-methyl-imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:In vitro inhibition of PAF-induced aggregation of rabbit washed platelets.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3DX8PubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50004615(4-(2-Chloro-phenyl)-2-methyl-6-[4-(2-methyl-imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:In vitro inhibition of PAF-induced aggregation of rabbit washed platelets.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3DX8PubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50004630(4-(2-Chloro-phenyl)-2-methyl-6-[4-(2-methyl-imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:In vitro inhibition of PAF-induced aggregation of rabbit washed platelets.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3DX8PubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50004617(4-(2-Chloro-phenyl)-6-methyl-2-[4-(2-methyl-pyridi...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:In vitro inhibition of PAF-induced aggregation of rabbit washed platelets.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3DX8PubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50004637(4-(2-Chloro-phenyl)-6-methyl-2-[4-(2-methyl-imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:In vitro inhibition of PAF-induced aggregation of rabbit washed platelets.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3DX8PubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50004650(6-Methyl-2-[4-(2-methyl-imidazo[4,5-c]pyridin-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:In vitro inhibition of PAF-induced aggregation of rabbit washed platelets.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3DX8PubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50004616(4-(2-Chloro-phenyl)-2-methyl-6-[4-(2-methyl-imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:In vitro inhibition of PAF-induced aggregation of rabbit washed platelets.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3DX8PubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50004645(4-Benzo[b]thiophen-3-yl-6-methyl-2-[4-(2-methyl-im...)copy SMILEScopy InChI
Affinity DataIC50: 3.10nMAssay Description:In vitro inhibition of PAF-induced aggregation of rabbit washed platelets.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3DX8PubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50004646(4-Benzo[1,3]dioxol-4-yl-6-methyl-2-[4-(2-methyl-im...)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:In vitro inhibition of PAF-induced aggregation of rabbit washed platelets.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3DX8PubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50004631(5-tert-Butylcarbamoyl-4-(2-chloro-phenyl)-6-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:In vitro inhibition of PAF-induced aggregation of rabbit washed platelets.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3DX8PubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50004632(4-(2-Chloro-phenyl)-2-[4-(2-ethyl-imidazo[4,5-c]py...)copy SMILEScopy InChI
Affinity DataIC50: 3.40nMAssay Description:In vitro inhibition of PAF-induced aggregation of rabbit washed platelets.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3DX8PubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50004633((S)-4-(2-Chloro-phenyl)-6-methyl-2-[4-(2-methyl-im...)copy SMILEScopy InChI
Affinity DataIC50: 4.30nMAssay Description:In vitro inhibition of PAF-induced aggregation of rabbit washed platelets.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3DX8PubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50004641(4-(2-Chloro-phenyl)-6-methyl-2-[4-(6-methyl-imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:In vitro inhibition of PAF-induced aggregation of rabbit washed platelets.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3DX8PubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50004625(5-Carbamoyl-4-(2-chloro-phenyl)-6-methyl-2-[4-(2-m...)copy SMILEScopy InChI
Affinity DataIC50: 5.60nMAssay Description:In vitro inhibition of PAF-induced aggregation of rabbit washed platelets.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3DX8PubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50004648(4-(2-Chloro-phenyl)-6-methyl-5-(pyridin-2-ylcarbam...)copy SMILEScopy InChI
Affinity DataIC50: 5.90nMAssay Description:In vitro inhibition of PAF-induced aggregation of rabbit washed platelets.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3DX8PubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50004642(4-(2-Chloro-phenyl)-2-[4-(2,4-dimethyl-thiazol-5-y...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:In vitro inhibition of PAF-induced aggregation of rabbit washed platelets.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3DX8PubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50004636(4-(2-Chloro-phenyl)-2-[4-(3,5-dimethyl-[1,2,4]tria...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:In vitro inhibition of PAF-induced aggregation of rabbit washed platelets.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3DX8PubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50004644(4-(2-Chloro-phenyl)-2-[4-(2,4-dimethyl-imidazol-1-...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:In vitro inhibition of PAF-induced aggregation of rabbit washed platelets.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3DX8PubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50004643(2-Chloro-6'-methyl-2'-[4-(2-methyl-imidazo[4,5-c]p...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:In vitro inhibition of PAF-induced aggregation of rabbit washed platelets.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3DX8PubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50004639(6'-Methyl-2'-[4-(2-methyl-imidazo[4,5-c]pyridin-1-...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:In vitro inhibition of PAF-induced aggregation of rabbit washed platelets.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3DX8PubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50004628(4-(2-Chloro-phenyl)-2-methyl-6-[4-(2-methyl-imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:In vitro inhibition of PAF-induced aggregation of rabbit washed platelets.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3DX8PubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50004626(4-(2-Chloro-phenyl)-6-methyl-5-(pyridin-2-ylcarbam...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:In vitro inhibition of PAF-induced aggregation of rabbit washed platelets.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3DX8PubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50004618(4-(2-Chloro-phenyl)-6-methyl-2-[4-(2-methyl-imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:In vitro inhibition of PAF-induced aggregation of rabbit washed platelets.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3DX8PubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50004627(4-(2-Chloro-phenyl)-6-methyl-2-[4-(2-methyl-imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:In vitro inhibition of PAF-induced aggregation of rabbit washed platelets.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3DX8PubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50004634(4-(4-Cyano-phenyl)-6-methyl-2-[4-(2-methyl-imidazo...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:In vitro inhibition of PAF-induced aggregation of rabbit washed platelets.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3DX8PubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50004651(4-(2-Chloro-phenyl)-6-methyl-2-[4-(2-methyl-imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:In vitro inhibition of PAF-induced aggregation of rabbit washed platelets.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3DX8PubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50004623(4-(2-Chloro-phenyl)-6-methyl-5-(pyridin-2-ylcarbam...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:In vitro inhibition of PAF-induced aggregation of rabbit washed platelets.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3DX8PubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50004638(6'-Methyl-2'-[4-(2-methyl-imidazo[4,5-c]pyridin-1-...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:In vitro inhibition of PAF-induced aggregation of rabbit washed platelets.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3DX8PubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50000714(3-[4-(2-Chloro-phenyl)-9-methyl-6H-1-thia-5,7,8,9a...)copy SMILEScopy InChI
Affinity DataIC50: 146nMAssay Description:In vitro inhibition of PAF-induced aggregation of rabbit washed platelets.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3DX8PubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50004649(2-[4-(2-Butyl-imidazo[4,5-c]pyridin-1-yl)-phenyl]-...)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:In vitro inhibition of PAF-induced aggregation of rabbit washed platelets.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3DX8PubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50004624(4-(2-Chloro-phenyl)-6-methyl-2-[4-(4-methyl-oxazol...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:In vitro inhibition of PAF-induced aggregation of rabbit washed platelets.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3DX8PubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50004629(4-(2-Chloro-phenyl)-2-[4-(6-methoxy-8-methyl-purin...)copy SMILEScopy InChI
Affinity DataIC50: 270nMAssay Description:In vitro inhibition of PAF-induced aggregation of rabbit washed platelets.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3DX8PubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50004640(4-(2-Chloro-phenyl)-6-methyl-2-[4-(4-methyl-imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 580nMAssay Description:In vitro inhibition of PAF-induced aggregation of rabbit washed platelets.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3DX8PubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50004621(4-(2-Chloro-phenyl)-6-methyl-2-[4-(2-oxo-2,3-dihyd...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:In vitro inhibition of PAF-induced aggregation of rabbit washed platelets.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3DX8PubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50004619(4-(2-Chloro-phenyl)-2-[4-(3,5-dimethyl-[1,2,4]tria...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:In vitro inhibition of PAF-induced aggregation of rabbit washed platelets.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3DX8PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50004633((S)-4-(2-Chloro-phenyl)-6-methyl-2-[4-(2-methyl-im...)copy SMILEScopy InChI
Affinity DataIC50: 6.60E+3nMAssay Description:Displacement of [3H]nitrendipine from L-type calcium channel of bovine frontal cortex membranes.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3DX8PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50004633((S)-4-(2-Chloro-phenyl)-6-methyl-2-[4-(2-methyl-im...)copy SMILEScopy InChI
Affinity DataIC50: 6.80E+3nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3DX8PubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50004620(4-(2-Chloro-phenyl)-6-methyl-2-[4-(6-methyl-pyridi...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of PAF-induced aggregation of rabbit washed platelets.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3DX8PubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50004635(4-(2-Chloro-phenyl)-2-[4-(3,5-dimethyl-pyrazol-1-y...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of PAF-induced aggregation of rabbit washed platelets.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3DX8PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50004633((S)-4-(2-Chloro-phenyl)-6-methyl-2-[4-(2-methyl-im...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]-diltiazem from L-type calcium channel of bovine frontal cortex membranes.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3DX8PubMed