Compile Data Set for Download or QSAR
Found 29 Enz. Inhib. hit(s) with all data for entry = 50036338
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Searle Research& Development

Curated by ChEMBL
LigandPNGBDBM50031555((S)-3-[3-(4-Carbamimidoyl-phenylcarbamoyl)-propion...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of collagen-induced canine platelet aggregation in vitro (blood is pooled from more than 2 dogs).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4K49PubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Searle Research& Development

Curated by ChEMBL
LigandPNGBDBM50031545((S)-3-Benzo[1,3]dioxol-5-yl-3-[3-(4-carbamimidoyl-...)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Inhibition of collagen-induced canine platelet aggregation in vitro (blood is pooled from more than 2 dogs).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4K49PubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Searle Research& Development

Curated by ChEMBL
LigandPNGBDBM50031565((S)-3-[3-(4-Carbamimidoyl-phenylcarbamoyl)-propion...)copy SMILEScopy InChI
Affinity DataIC50: 67nMAssay Description:Inhibition of collagen-induced canine platelet aggregation in vitro (blood is pooled from more than 2 dogs).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4K49PubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Searle Research& Development

Curated by ChEMBL
LigandPNGBDBM50031553(3-[3-(4-Carbamimidoyl-phenylcarbamoyl)-propionylam...)copy SMILEScopy InChI
Affinity DataIC50: 101nMAssay Description:Inhibition of collagen-induced canine platelet aggregation in vitro (blood is pooled from more than 2 dogs).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4K49PubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Searle Research& Development

Curated by ChEMBL
LigandPNGBDBM50031559(3-Benzo[1,3]dioxol-5-yl-3-[3-(4-carbamimidoyl-phen...)copy SMILEScopy InChI
Affinity DataIC50: 104nMAssay Description:Inhibition of collagen-induced canine platelet aggregation in vitro (blood is pooled from more than 2 dogs).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4K49PubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Searle Research& Development

Curated by ChEMBL
LigandPNGBDBM50031561(3-[3-(4-Carbamimidoyl-phenylcarbamoyl)-propionylam...)copy SMILEScopy InChI
Affinity DataIC50: 108nMAssay Description:Inhibition of collagen-induced canine platelet aggregation in vitro (blood is pooled from more than 2 dogs).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4K49PubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Searle Research& Development

Curated by ChEMBL
LigandPNGBDBM50031544(3-[3-(4-Carbamimidoyl-phenylcarbamoyl)-propionylam...)copy SMILEScopy InChI
Affinity DataIC50: 115nMAssay Description:Inhibition of collagen-induced canine platelet aggregation in vitro (blood is pooled from more than 2 dogs).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4K49PubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Searle Research& Development

Curated by ChEMBL
LigandPNGBDBM50031547(3-[3-(4-Carbamimidoyl-phenylcarbamoyl)-propionylam...)copy SMILEScopy InChI
Affinity DataIC50: 122nMAssay Description:Inhibition of collagen-induced canine platelet aggregation in vitro (blood is pooled from more than 2 dogs).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4K49PubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Searle Research& Development

Curated by ChEMBL
LigandPNGBDBM50031556((Aminobenzamidino)succinyl analogue | (S)-3-[3-(4-...)copy SMILEScopy InChI
Affinity DataIC50: 133nMAssay Description:Inhibition of collagen-induced canine platelet aggregation in vitro (blood is pooled from more than 2 dogs).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4K49PubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Searle Research& Development

Curated by ChEMBL
LigandPNGBDBM50031556((Aminobenzamidino)succinyl analogue | (S)-3-[3-(4-...)copy SMILEScopy InChI
Affinity DataIC50: 133nMAssay Description:Inhibition of collagen-induced canine platelet aggregation in vitro (blood is pooled from more than 2 dogs).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4K49PubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Searle Research& Development

Curated by ChEMBL
LigandPNGBDBM50031563(3-[3-(4-Carbamimidoyl-phenylcarbamoyl)-propionylam...)copy SMILEScopy InChI
Affinity DataIC50: 158nMAssay Description:Inhibition of collagen-induced canine platelet aggregation in vitro (blood is pooled from more than 2 dogs).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4K49PubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Searle Research& Development

Curated by ChEMBL
LigandPNGBDBM50031550(3-[3-(4-Carbamimidoyl-phenylcarbamoyl)-propionylam...)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Inhibition of collagen-induced canine platelet aggregation in vitro (blood is pooled from more than 2 dogs).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4K49PubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Searle Research& Development

Curated by ChEMBL
LigandPNGBDBM50031557(3-[3-(4-Carbamimidoyl-phenylcarbamoyl)-propionylam...)copy SMILEScopy InChI
Affinity DataIC50: 224nMAssay Description:Inhibition of collagen-induced canine platelet aggregation in vitro (blood is pooled from more than 2 dogs).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4K49PubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Searle Research& Development

Curated by ChEMBL
LigandPNGBDBM50031554(3-[3-(4-Carbamimidoyl-phenylcarbamoyl)-propionylam...)copy SMILEScopy InChI
Affinity DataIC50: 256nMAssay Description:Inhibition of collagen-induced canine platelet aggregation in vitro (blood is pooled from more than 2 dogs).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4K49PubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Searle Research& Development

Curated by ChEMBL
LigandPNGBDBM50031552(3-[3-(4-Carbamimidoyl-phenylcarbamoyl)-propionylam...)copy SMILEScopy InChI
Affinity DataIC50: 294nMAssay Description:Inhibition of collagen-induced canine platelet aggregation in vitro (blood is pooled from more than 2 dogs).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4K49PubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Searle Research& Development

Curated by ChEMBL
LigandPNGBDBM50031539(3-[3-(4-Carbamimidoyl-phenylcarbamoyl)-propionylam...)copy SMILEScopy InChI
Affinity DataIC50: 302nMAssay Description:Inhibition of collagen-induced canine platelet aggregation in vitro (blood is pooled from more than 2 dogs).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4K49PubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Searle Research& Development

Curated by ChEMBL
LigandPNGBDBM50031540(3-[3-(4-Carbamimidoyl-phenylcarbamoyl)-propionylam...)copy SMILEScopy InChI
Affinity DataIC50: 321nMAssay Description:Inhibition of collagen-induced canine platelet aggregation in vitro (blood is pooled from more than 2 dogs).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4K49PubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Searle Research& Development

Curated by ChEMBL
LigandPNGBDBM50031558(3-[3-(4-Carbamimidoyl-phenylcarbamoyl)-propionylam...)copy SMILEScopy InChI
Affinity DataIC50: 491nMAssay Description:Inhibition of collagen-induced canine platelet aggregation in vitro (blood is pooled from more than 2 dogs).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4K49PubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Searle Research& Development

Curated by ChEMBL
LigandPNGBDBM50031566(3-[3-(4-Carbamimidoyl-phenylcarbamoyl)-propionylam...)copy SMILEScopy InChI
Affinity DataIC50: 580nMAssay Description:Inhibition of collagen-induced canine platelet aggregation in vitro (blood is pooled from more than 2 dogs).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4K49PubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Searle Research& Development

Curated by ChEMBL
LigandPNGBDBM50031551(3-[5-(4-Carbamimidoyl-phenyl)-pent-4-enoylamino]-p...)copy SMILEScopy InChI
Affinity DataIC50: 904nMAssay Description:Inhibition of collagen-induced canine platelet aggregation in vitro (blood is pooled from more than 2 dogs).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4K49PubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Searle Research& Development

Curated by ChEMBL
LigandPNGBDBM50031564(3-[3-(4-Carbamimidoyl-phenylcarbamoyl)-propionylam...)copy SMILEScopy InChI
Affinity DataIC50: 1.09E+3nMAssay Description:Inhibition of collagen-induced canine platelet aggregation in vitro (blood is pooled from more than 2 dogs).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4K49PubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Searle Research& Development

Curated by ChEMBL
LigandPNGBDBM50031546(3-[3-(4-Carbamimidoyl-phenylcarbamoyl)-propionylam...)copy SMILEScopy InChI
Affinity DataIC50: 1.17E+3nMAssay Description:Inhibition of collagen-induced canine platelet aggregation in vitro (blood is pooled from more than 2 dogs).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4K49PubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Searle Research& Development

Curated by ChEMBL
LigandPNGBDBM50031548((Aminobenzamidino)succinyl analogue | {amino[4-(3-...)copy SMILEScopy InChI
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of collagen-induced canine platelet aggregation in vitro (blood is pooled from more than 2 dogs).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4K49PubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Searle Research& Development

Curated by ChEMBL
LigandPNGBDBM50031538(3-[5-(4-Carbamimidoyl-phenyl)-pentanoylamino]-buty...)copy SMILEScopy InChI
Affinity DataIC50: 2.87E+3nMAssay Description:Inhibition of collagen-induced canine platelet aggregation in vitro (blood is pooled from more than 2 dogs).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4K49PubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Searle Research& Development

Curated by ChEMBL
LigandPNGBDBM50031542(3-[5-(4-Carbamimidoyl-phenyl)-pentanoylamino]-4-ph...)copy SMILEScopy InChI
Affinity DataIC50: 4.72E+3nMAssay Description:Inhibition of collagen-induced canine platelet aggregation in vitro (blood is pooled from more than 2 dogs).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4K49PubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Searle Research& Development

Curated by ChEMBL
LigandPNGBDBM50031541(3-[5-(4-Carbamimidoyl-phenyl)-pentanoylamino]-3-ph...)copy SMILEScopy InChI
Affinity DataIC50: 4.88E+3nMAssay Description:Inhibition of collagen-induced canine platelet aggregation in vitro (blood is pooled from more than 2 dogs).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4K49PubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Searle Research& Development

Curated by ChEMBL
LigandPNGBDBM50031562(3-[3-(4-Carbamimidoyl-phenylcarbamoyl)-propionylam...)copy SMILEScopy InChI
Affinity DataIC50: 4.94E+3nMAssay Description:Inhibition of collagen-induced canine platelet aggregation in vitro (blood is pooled from more than 2 dogs).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4K49PubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Searle Research& Development

Curated by ChEMBL
LigandPNGBDBM50031543(3-[5-(4-Carbamimidoyl-phenyl)-pentanoylamino]-prop...)copy SMILEScopy InChI
Affinity DataIC50: 5.88E+3nMAssay Description:Inhibition of collagen-induced canine platelet aggregation in vitro (blood is pooled from more than 2 dogs).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4K49PubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Searle Research& Development

Curated by ChEMBL
LigandPNGBDBM50031549(3-[4-(4-Carbamimidoyl-phenylamino)-butyrylamino]-p...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of collagen-induced canine platelet aggregation in vitro (blood is pooled from more than 2 dogs).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4K49PubMed