Compile Data Set for Download or QSAR
Found 46 Enz. Inhib. hit(s) with all data for entry = 50036838
TargetDihydrofolate reductase(Escherichia coli)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibitory concentration against Escherichia coli Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W096N3PubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibitory concentration against Lactobacillus casei Dihydrofolate reductaseMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibitory concentration against recombinant human (rh) Dihydrofolate reductaseMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50008294(2-(4-(((2-amino-4-oxo-1,4-dihydroquinazolin-6-yl)m...)copy SMILEScopy InChI
Affinity DataIC50: 55nMAssay Description:Inhibitory concentration against Lactobacillus casei Thymidylate synthase (TS).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W096N3PubMed
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50008294(2-(4-(((2-amino-4-oxo-1,4-dihydroquinazolin-6-yl)m...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibitory concentration against Escherichia coli Thymidylate synthase (TS).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W096N3PubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50030819((S)-2-(4-(2-(2,4-diaminofuro[2,3-d]pyrimidin-5-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibitory concentration against Lactobacillus casei Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W096N3PubMed
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50008294(2-(4-(((2-amino-4-oxo-1,4-dihydroquinazolin-6-yl)m...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibitory concentration against recombinant human (rh) Thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W096N3PubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50091145((S)-2-(4-(((2,4-diaminofuro[2,3-d]pyrimidin-5-yl)m...)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibitory concentration against Lactobacillus casei Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W096N3PubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50091145((S)-2-(4-(((2,4-diaminofuro[2,3-d]pyrimidin-5-yl)m...)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibitory concentration against recombinant human (rh) Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W096N3PubMedMMDB
TargetThymidylate synthase(Rattus norvegicus)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50008294(2-(4-(((2-amino-4-oxo-1,4-dihydroquinazolin-6-yl)m...)copy SMILEScopy InChI
Affinity DataIC50: 360nMAssay Description:Inhibitory concentration against rat Thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W096N3PubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50091147(2-{4-[2-(2,4-Diamino-furo[2,3-d]pyrimidin-5-yl)-1-...)copy SMILEScopy InChI
Affinity DataIC50: 420nMAssay Description:Inhibitory concentration against recombinant human (rh) Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W096N3PubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50030820((S)-2-(4-((2,4-diaminofuro[2,3-d]pyrimidin-5-yl)me...)copy SMILEScopy InChI
Affinity DataIC50: 450nMAssay Description:Inhibitory concentration against recombinant human (rh) Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W096N3PubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50030820((S)-2-(4-((2,4-diaminofuro[2,3-d]pyrimidin-5-yl)me...)copy SMILEScopy InChI
Affinity DataIC50: 560nMAssay Description:Inhibitory concentration against Lactobacillus casei Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W096N3PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50030820((S)-2-(4-((2,4-diaminofuro[2,3-d]pyrimidin-5-yl)me...)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:Inhibitory concentration against Toxoplasma gondii Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W096N3PubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50030819((S)-2-(4-(2-(2,4-diaminofuro[2,3-d]pyrimidin-5-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory concentration against recombinant human (rh) Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W096N3PubMed
TargetDihydrofolate reductase(Escherichia coli)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50369577(CHEMBL1237205 | CHEMBL2092925)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory concentration against Escherichia coli Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W096N3PubMed
TargetDihydrofolate reductase(Escherichia coli)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50091147(2-{4-[2-(2,4-Diamino-furo[2,3-d]pyrimidin-5-yl)-1-...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory concentration against Escherichia coli Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W096N3PubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50091147(2-{4-[2-(2,4-Diamino-furo[2,3-d]pyrimidin-5-yl)-1-...)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibitory concentration against Toxoplasma gondii Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W096N3PubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50091147(2-{4-[2-(2,4-Diamino-furo[2,3-d]pyrimidin-5-yl)-1-...)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibitory concentration against Lactobacillus casei Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W096N3PubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50369577(CHEMBL1237205 | CHEMBL2092925)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibitory concentration against recombinant human (rh) Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W096N3PubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50369577(CHEMBL1237205 | CHEMBL2092925)copy SMILEScopy InChI
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibitory concentration against Toxoplasma gondii Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W096N3PubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50369577(CHEMBL1237205 | CHEMBL2092925)copy SMILEScopy InChI
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibitory concentration against Lactobacillus casei Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W096N3PubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50030818((S)-2-(4-{[(2,4-Diamino-furo[2,3-d]pyrimidin-5-ylm...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W096N3PubMed
TargetDihydrofolate reductase(Escherichia coli)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50369577(CHEMBL1237205 | CHEMBL2092925)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibitory concentration against Escherichia coli Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W096N3PubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50091145((S)-2-(4-(((2,4-diaminofuro[2,3-d]pyrimidin-5-yl)m...)copy SMILEScopy InChI
Affinity DataIC50: 1.98E+4nMAssay Description:Inhibitory concentration against Toxoplasma gondii Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W096N3PubMedMMDB
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50369577(CHEMBL1237205 | CHEMBL2092925)copy SMILEScopy InChI
Affinity DataIC50: 4.20E+4nMAssay Description:Inhibitory concentration against recombinant human (rh) Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W096N3PubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50369577(CHEMBL1237205 | CHEMBL2092925)copy SMILEScopy InChI
Affinity DataIC50: 8.40E+4nMAssay Description:Inhibitory concentration against Lactobacillus casei Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W096N3PubMed
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50091147(2-{4-[2-(2,4-Diamino-furo[2,3-d]pyrimidin-5-yl)-1-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration against Escherichia coli Thymidylate synthase (TS).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W096N3PubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50369577(CHEMBL1237205 | CHEMBL2092925)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+5nMAssay Description:Inhibitory concentration against Toxoplasma gondii Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W096N3PubMed
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50091145((S)-2-(4-(((2,4-diaminofuro[2,3-d]pyrimidin-5-yl)m...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibitory concentration against recombinant human (rh) Thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W096N3PubMed
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50091145((S)-2-(4-(((2,4-diaminofuro[2,3-d]pyrimidin-5-yl)m...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibitory concentration against Lactobacillus casei Thymidylate synthase (TS).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W096N3PubMed
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50030820((S)-2-(4-((2,4-diaminofuro[2,3-d]pyrimidin-5-yl)me...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibitory concentration against Lactobacillus casei Thymidylate synthase (TS).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W096N3PubMed
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50030820((S)-2-(4-((2,4-diaminofuro[2,3-d]pyrimidin-5-yl)me...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibitory concentration against recombinant human (rh) Thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W096N3PubMed
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50030819((S)-2-(4-(2-(2,4-diaminofuro[2,3-d]pyrimidin-5-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibitory concentration against Lactobacillus casei Thymidylate synthase (TS).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W096N3PubMed
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50030819((S)-2-(4-(2-(2,4-diaminofuro[2,3-d]pyrimidin-5-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+5nMAssay Description:Inhibitory concentration against recombinant human (rh) Thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W096N3PubMed
TargetThymidylate synthase(Rattus norvegicus)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50369577(CHEMBL1237205 | CHEMBL2092925)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+5nMAssay Description:Inhibitory concentration against rat Thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W096N3PubMed
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50369577(CHEMBL1237205 | CHEMBL2092925)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+5nMAssay Description:Inhibitory concentration against Lactobacillus casei Thymidylate synthase (TS).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W096N3PubMed
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50369577(CHEMBL1237205 | CHEMBL2092925)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+5nMAssay Description:Inhibitory concentration against recombinant human (rh) Thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W096N3PubMed
TargetThymidylate synthase(Rattus norvegicus)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50369577(CHEMBL1237205 | CHEMBL2092925)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+5nMAssay Description:Inhibitory concentration against rat Thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W096N3PubMed
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50091147(2-{4-[2-(2,4-Diamino-furo[2,3-d]pyrimidin-5-yl)-1-...)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+5nMAssay Description:Inhibitory concentration against Lactobacillus casei Thymidylate synthase (TS).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W096N3PubMed
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50369577(CHEMBL1237205 | CHEMBL2092925)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+5nMAssay Description:Inhibitory concentration against Escherichia coli Thymidylate synthase (TS).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W096N3PubMed
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50369577(CHEMBL1237205 | CHEMBL2092925)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+5nMAssay Description:Inhibitory concentration against recombinant human (rh) Thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W096N3PubMed
TargetThymidylate synthase(Rattus norvegicus)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50091147(2-{4-[2-(2,4-Diamino-furo[2,3-d]pyrimidin-5-yl)-1-...)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+5nMAssay Description:Inhibitory concentration against rat Thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W096N3PubMed
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50369577(CHEMBL1237205 | CHEMBL2092925)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+5nMAssay Description:Inhibitory concentration against Lactobacillus casei Thymidylate synthase (TS).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W096N3PubMed
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50091147(2-{4-[2-(2,4-Diamino-furo[2,3-d]pyrimidin-5-yl)-1-...)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+5nMAssay Description:Inhibitory concentration against recombinant human (rh) Thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W096N3PubMed
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50369577(CHEMBL1237205 | CHEMBL2092925)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+5nMAssay Description:Inhibitory concentration against Escherichia coli Thymidylate synthase (TS).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W096N3PubMed