Compile Data Set for Download or QSAR
Found 11 Enz. Inhib. hit(s) with all data for entry = 50037023
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50113299(5-[3-Nitro-4-(6-nitro-benzothiazol-2-ylsulfanyl)-b...)copy SMILEScopy InChI
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of human Protein-tyrosine phosphatase 1B (PTP1B) dephosphorylation of insulin receptor peptideMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SB46F1PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50113293(4-[4-Oxo-5-(3-phenyl-allylidene)-2-thioxo-thiazoli...)copy SMILEScopy InChI
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of human Protein-tyrosine phosphatase 1B (PTP1B) dephosphorylation of insulin receptor peptideMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SB46F1PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50113297(3-(4,5-Bis-biphenyl-4-yl-1H-imidazol-2-yl)-phenol ...)copy SMILEScopy InChI
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of human Protein-tyrosine phosphatase 1B (PTP1B) dephosphorylation of insulin receptor peptideMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SB46F1PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50113296(2-Hydroxy-4-[5-(4-oxo-3-phenyl-2-phenylimino-thiaz...)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human Protein-tyrosine phosphatase 1B (PTP1B) dephosphorylation of insulin receptor peptideMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SB46F1PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50113295(1-[5-(4-Chloro-phenyl)-2-phenyl-2H-pyrazol-3-yl]-3...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human Protein-tyrosine phosphatase 1B (PTP1B) dephosphorylation of insulin receptor peptideMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SB46F1PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50113303(2-Chloro-4-{5-[1-(3-chloro-phenyl)-3-methyl-5-oxo-...)copy SMILEScopy InChI
Affinity DataIC50: 1.93E+4nMAssay Description:Inhibition of human Protein-tyrosine phosphatase 1B (PTP1B) dephosphorylation of insulin receptor peptideMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SB46F1PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50113302(CHEMBL420925 | N-[1-(4-Hydroxy-phenylcarbamoyl)-2-...)copy SMILEScopy InChI
Affinity DataIC50: 2.15E+4nMAssay Description:Inhibition of human Protein-tyrosine phosphatase 1B (PTP1B) dephosphorylation of insulin receptor peptideMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SB46F1PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50113301(4-(3-Benzyl-4-oxo-2-thioxo-thiazolidin-5-ylideneme...)copy SMILEScopy InChI
Affinity DataIC50: 2.16E+4nMAssay Description:Inhibition of human Protein-tyrosine phosphatase 1B (PTP1B) dephosphorylation of insulin receptor peptideMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SB46F1PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50113294(2-[2-(5-Bromo-furan-2-carbonyloxy)-acetylamino]-be...)copy SMILEScopy InChI
Affinity DataIC50: 3.44E+4nMAssay Description:Inhibition of human Protein-tyrosine phosphatase 1B (PTP1B) dephosphorylation of insulin receptor peptideMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SB46F1PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50113300(Acetic acid 4-(2-benzo[1,3]dioxol-5-yl-5-oxo-oxazo...)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of human Protein-tyrosine phosphatase 1B (PTP1B) dephosphorylation of insulin receptor peptideMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SB46F1PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50113298(3,4-Dichloro-N-[4-(4-chloro-benzenesulfonyl)-5-met...)copy SMILEScopy InChI
Affinity DataIC50: 6.39E+4nMAssay Description:Inhibition of human Protein-tyrosine phosphatase 1B (PTP1B) dephosphorylation of insulin receptor peptideMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SB46F1PubMed