Compile Data Set for Download or QSAR
Found 40 Enz. Inhib. hit(s) with all data for entry = 50037320
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50370403(CHEMBL177829)copy SMILEScopy InChI
Affinity DataKi:  0.700nMAssay Description:Binding affinity to Sigma opioid receptor type 1 in guinea pig brain homogenate with 0.5 nM of [3H](+)-PENT as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K64JTVPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50370403(CHEMBL177829)copy SMILEScopy InChI
Affinity DataKi:  4.5nMAssay Description:Binding affinity to Sigma opioid receptor type 2 in guinea pig brain homogenate with 4 nM of [3H](+)-DTG as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K64JTVPubMed
Target3-dehydroquinate synthase(Escherichia coli (strain K12))
TBA

Curated by ChEMBL
LigandPNGBDBM50028881((1R,3S,4S)-1,4-Dihydroxy-3-phosphonomethyl-cyclohe...)copy SMILEScopy InChI
Affinity DataKi:  220nMAssay Description:Compound was evaluated for its inhibitory constant against 3-dehydroquinate synthaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K64JTVPubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50409932(CHEMBL178537)copy SMILEScopy InChI
Affinity DataKi:  250nMAssay Description:Compound was tested for inhibitory activity against FK506 binding protein 12 (FKBP12)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K64JTVPubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50370391(CHEMBL175813)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against human recombinant arginine vasopressin V2 receptor using [3H]AVP as radioligand in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K64JTVPubMed
TargetType-2 angiotensin II receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50370408(CHEMBL177435)copy SMILEScopy InChI
Affinity DataIC50: 6.70nMAssay Description:In vitro binding affinity against angiotensin II AT-2 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K64JTVPubMed
TargetVasopressin V2 receptor(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50370394(CHEMBL368791)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against arginine vasopressin V2 receptor using [3H]AVP as radioligand in rat adrenal medullaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K64JTVPubMed
TargetVasopressin V2 receptor(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50370404(CHEMBL175930)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against arginine vasopressin V2 receptor using [3H]AVP as radioligand in rat adrenal medullaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K64JTVPubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50370394(CHEMBL368791)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against human recombinant arginine vasopressin V2 receptor using [3H]AVP as radioligand in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K64JTVPubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50370404(CHEMBL175930)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against human recombinant arginine vasopressin V2 receptor using [3H]AVP as radioligand in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K64JTVPubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50028866(CHEMBL297271 | N-[(1S,2R)-2-(4-Hydroxy-phenyl)-ind...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K64JTVPubMed
TargetVasopressin V2 receptor(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50370397(CHEMBL177556)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibitory activity against arginine vasopressin V2 receptor using [3H]AVP as radioligand in rat adrenal medullaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K64JTVPubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50370397(CHEMBL177556)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibitory activity against human recombinant arginine vasopressin V2 receptor using [3H]AVP as radioligand in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K64JTVPubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50370400(CHEMBL176264)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibitory activity against human recombinant arginine vasopressin V2 receptor using [3H]AVP as radioligand in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K64JTVPubMed
TargetType-2 angiotensin II receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50370405(CHEMBL535139 | PD-123177)copy SMILEScopy InChI
Affinity DataIC50: 66nMAssay Description:In vitro binding affinity against angiotensin II AT-2 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K64JTVPubMed
TargetVasopressin V2 receptor(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50370392(CHEMBL369712)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against arginine vasopressin V2 receptor using [3H]AVP as radioligand in rat adrenal medullaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K64JTVPubMed
TargetVasopressin V2 receptor(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50370402(CHEMBL441498)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibitory activity against arginine vasopressin V2 receptor using [3H]AVP as radioligand in rat adrenal medullaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K64JTVPubMed
TargetVasopressin V2 receptor(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50370398(CHEMBL175211)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibitory activity against arginine vasopressin V2 receptor using [3H]AVP as radioligand in rat adrenal medullaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K64JTVPubMed
TargetVasopressin V2 receptor(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50370395(CHEMBL175411)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibitory activity against arginine vasopressin V2 receptor using [3H]AVP as radioligand in rat adrenal medullaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K64JTVPubMed
TargetVasopressin V2 receptor(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM35714(CHEMBL420762 | Mozavaptan | N-[4-(5-Dimethylamino-...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibitory activity against arginine vasopressin V2 receptor using [3H]AVP as radioligand in rat adrenal medullaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K64JTVPubMed
TargetVasopressin V2 receptor(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50370391(CHEMBL175813)copy SMILEScopy InChI
Affinity DataIC50: 310nMAssay Description:Inhibitory activity against arginine vasopressin V2 receptor using [3H]AVP as radioligand in rat adrenal medullaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K64JTVPubMed
TargetVasopressin V2 receptor(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50370400(CHEMBL176264)copy SMILEScopy InChI
Affinity DataIC50: 380nMAssay Description:Inhibitory activity against arginine vasopressin V2 receptor using [3H]AVP as radioligand in rat adrenal medullaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K64JTVPubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM35714(CHEMBL420762 | Mozavaptan | N-[4-(5-Dimethylamino-...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibitory activity against human recombinant arginine vasopressin V2 receptor using [3H]AVP as radioligand in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K64JTVPubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50028868(CHEMBL41233 | N-[2-(4-Amino-phenyl)-1-phenyl-ethyl...)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K64JTVPubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50030448(8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN | CHEMBL269732 ...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity towards recombinant FK506 binding protein 12 to determine the FKBP binding property of the compoundMore data for this Ligand-Target Pair
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50028880((3S,4R)-3-Ethyl-4-phenyl-3-(3-phenyl-propyl)-1-(2,...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K64JTVPubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50005944(2,2-Dimethyl-dodecanoic acid (2,4,6-trimethoxy-phe...)copy SMILEScopy InChI
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT)More data for this Ligand-Target Pair
TargetVasopressin V2 receptor(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50370399(CHEMBL360272)copy SMILEScopy InChI
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibitory activity against arginine vasopressin V2 receptor using [3H]AVP as radioligand in rat adrenal medullaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K64JTVPubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50028888((3S,4R)-1-(4-Methoxy-phenyl)-3,4-diphenyl-3-(3-phe...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K64JTVPubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50028877((3S,4R)-1-(4-Methoxy-phenyl)-3,4-diphenyl-3-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K64JTVPubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50370396(CHEMBL178591)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K64JTVPubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50370398(CHEMBL175211)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against human recombinant arginine vasopressin V2 receptor using [3H]AVP as radioligand in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K64JTVPubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50370409(CHEMBL332150)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K64JTVPubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50370395(CHEMBL175411)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against human recombinant arginine vasopressin V2 receptor using [3H]AVP as radioligand in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K64JTVPubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50370402(CHEMBL441498)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against human recombinant arginine vasopressin V2 receptor using [3H]AVP as radioligand in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K64JTVPubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50370407(CHEMBL49500)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K64JTVPubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50370399(CHEMBL360272)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against human recombinant arginine vasopressin V2 receptor using [3H]AVP as radioligand in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K64JTVPubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50370410(CHEMBL369660)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K64JTVPubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50028867((3R,4S)-1,4-Bis-(4-methoxy-phenyl)-3-(3-phenyl-pro...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K64JTVPubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50028867((3R,4S)-1,4-Bis-(4-methoxy-phenyl)-3-(3-phenyl-pro...)copy SMILEScopy InChI
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K64JTVPubMed