Compile Data Set for Download or QSAR
Found 46 Enz. Inhib. hit(s) with all data for entry = 50037657
TargetAurora kinase A(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM13534(CHEMBL572878 | N-[4-({4-[(3-methyl-1H-pyrazol-5-yl...)copy SMILEScopy InChI
Affinity DataKi:  0.600nMAssay Description:In vitro inhibition constant for Aurora-AMore data for this Ligand-Target Pair
TargetAurora kinase C(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM13534(CHEMBL572878 | N-[4-({4-[(3-methyl-1H-pyrazol-5-yl...)copy SMILEScopy InChI
Affinity DataKi:  4.60nMAssay Description:In vitro inhibition constant for Aurora-CMore data for this Ligand-Target Pair
TargetAurora kinase B(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM13534(CHEMBL572878 | N-[4-({4-[(3-methyl-1H-pyrazol-5-yl...)copy SMILEScopy InChI
Affinity DataKi:  18nMAssay Description:In vitro inhibition constant for Aurora-BMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM13534(CHEMBL572878 | N-[4-({4-[(3-methyl-1H-pyrazol-5-yl...)copy SMILEScopy InChI
Affinity DataKi:  30nMAssay Description:In vitro inhibition constant for FLT-3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FXVPubMed
TargetAurora kinase A(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50181550(CHEMBL201297 | N-(3-fluorophenyl)-2-(2-{[6-methoxy...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:In vitro inhibition constant for Aurora-AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FXVPubMed
TargetAurora kinase A(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50027188(CHEMBL202241)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of Aurora A kinase activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FXVPubMed
TargetAurora kinase A(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50027228(CHEMBL201953)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of Aurora A kinase activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FXVPubMed
TargetAurora kinase A(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50027191(CHEMBL202593)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of Aurora A kinase activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FXVPubMed
TargetAurora kinase A(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50027189(CHEMBL381721)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of Aurora A kinase activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FXVPubMed
TargetAurora kinase A(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50027186(CHEMBL377289)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of Aurora A kinase activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FXVPubMed
TargetAurora kinase A(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50181532(CHEMBL201307 | N-(3-fluorophenyl)-2-(2-(7-(3-(4-(h...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of Aurora A kinase activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FXVPubMed
TargetAurora kinase A(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50181547(CHEMBL202567 | N-(4-fluorophenyl)-2-{[6-methoxy-7-...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:In vitro inhibition constant for Aurora-AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FXVPubMed
TargetAurora kinase A(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50027190(CHEMBL202198)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of Aurora A kinase activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FXVPubMed
TargetAurora kinase A(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50027192(CHEMBL380478)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of Aurora A kinase activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FXVPubMed
TargetAurora kinase A(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50181537(CHEMBL201197 | N-(2,3-difluorophenyl)-2-{2-[(7-{3-...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:In vitro inhibition constant for Aurora-AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FXVPubMed
TargetAurora kinase A(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50181542(CHEMBL373013 | N-(3-fluorophenyl)-2-(2-(7-(3-(2-hy...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:In vitro inhibition constant for Aurora-AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FXVPubMed
TargetAurora kinase A(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50181535(CHEMBL201655 | N-(5-butyl-1,3-thiazol-2-yl)-6-meth...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:In vitro inhibition constant for Aurora-AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FXVPubMed
TargetAurora kinase A(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50181544(3-fluoro-N-({2-[(7-{3-[4-(hydroxymethyl)piperidin-...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:In vitro inhibition constant for Aurora-AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FXVPubMed
TargetAurora kinase A(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50181556(6-methoxy-N-(5-methyl-1,3-thiazol-2-yl)-7-(3-morph...)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:In vitro inhibition constant for Aurora-AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FXVPubMed
TargetAurora kinase A(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50181540(CHEMBL202026 | N-ethyl-2-(2-{[6-methoxy-7-(3-morph...)copy SMILEScopy InChI
Affinity DataIC50: 55nMAssay Description:In vitro inhibition constant for Aurora-AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FXVPubMed
TargetAurora kinase B(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM14210(4-(4-(N-benzoylamino)anilino)-6-methoxy-7-(3-(1-mo...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of in vitro Aurora-B kinase activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FXVPubMed
TargetAurora kinase A(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM14210(4-(4-(N-benzoylamino)anilino)-6-methoxy-7-(3-(1-mo...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of in vitro Aurora-A kinase activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FXVPubMed
TargetAurora kinase A(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50181557(2-{2-[(7-{3-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 106nMAssay Description:In vitro inhibition constant for Aurora-AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FXVPubMed
TargetAurora kinase A(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50181552(3-fluoro-N-({2-[(7-{3-[4-(hydroxymethyl)piperidin-...)copy SMILEScopy InChI
Affinity DataIC50: 111nMAssay Description:In vitro inhibition constant for Aurora-AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FXVPubMed
TargetAurora kinase A(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50181554(2-(2-{[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinaz...)copy SMILEScopy InChI
Affinity DataIC50: 158nMAssay Description:In vitro inhibition constant for Aurora-AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FXVPubMed
TargetAurora kinase B(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50273571(CHEMBL514409 | Hesperadin | N-(2-oxo-3-(phenyl(4-(...)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Inhibition of Aurora-B immunoprecipitated from mitotic cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FXVPubMed
TargetAurora kinase A(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50181538(2-[({2-[(7-{3-[(2S)-2-(hydroxymethyl)pyrrolidin-1-...)copy SMILEScopy InChI
Affinity DataIC50: 452nMAssay Description:In vitro inhibition constant for Aurora-AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FXVPubMed
TargetAurora kinase A(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50181534(CHEMBL202502 | N-(3-fluorophenyl)-2-(2-{[6-methoxy...)copy SMILEScopy InChI
Affinity DataIC50: 472nMAssay Description:In vitro inhibition constant for Aurora-AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FXVPubMed
TargetAurora kinase A(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50181549(CHEMBL203422 | N-[3-(dimethylamino)phenyl]-2-{2-[(...)copy SMILEScopy InChI
Affinity DataIC50: 483nMAssay Description:In vitro inhibition constant for Aurora-AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FXVPubMed
TargetAurora kinase A(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50181539(CHEMBL382804 | N-(3-fluorophenyl)-2-(2-{[6-methoxy...)copy SMILEScopy InChI
Affinity DataIC50: 578nMAssay Description:In vitro inhibition constant for Aurora-AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FXVPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50181532(CHEMBL201307 | N-(3-fluorophenyl)-2-(2-(7-(3-(4-(h...)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:Inhibitory activity against EGFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FXVPubMed
TargetAurora kinase A(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50181553(CHEMBL202370 | N-(4-fluorophenyl)-2-{[6-methoxy-7-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibition constant for Aurora-AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FXVPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50181532(CHEMBL201307 | N-(3-fluorophenyl)-2-(2-(7-(3-(4-(h...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FXVPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50181532(CHEMBL201307 | N-(3-fluorophenyl)-2-(2-(7-(3-(4-(h...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibitory activity against SRCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FXVPubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50181532(CHEMBL201307 | N-(3-fluorophenyl)-2-(2-(7-(3-(4-(h...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibitory activity against FAKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FXVPubMed
TargetFibroblast growth factor receptor 1/2/3/4(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50181532(CHEMBL201307 | N-(3-fluorophenyl)-2-(2-(7-(3-(4-(h...)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibitory activity against FGFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FXVPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50181532(CHEMBL201307 | N-(3-fluorophenyl)-2-(2-(7-(3-(4-(h...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against human hERG receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FXVPubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM14210(4-(4-(N-benzoylamino)anilino)-6-methoxy-7-(3-(1-mo...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of in vitro Plk1 kinase activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FXVPubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM14210(4-(4-(N-benzoylamino)anilino)-6-methoxy-7-(3-(1-mo...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of in vitro CDK1 kinase activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FXVPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50181532(CHEMBL201307 | N-(3-fluorophenyl)-2-(2-(7-(3-(4-(h...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibitory activity against IGFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FXVPubMed
TargetTyrosine-protein kinase CSK(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50181532(CHEMBL201307 | N-(3-fluorophenyl)-2-(2-(7-(3-(4-(h...)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibitory activity against CSKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FXVPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50181532(CHEMBL201307 | N-(3-fluorophenyl)-2-(2-(7-(3-(4-(h...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibitory activity against JAK3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FXVPubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50181532(CHEMBL201307 | N-(3-fluorophenyl)-2-(2-(7-(3-(4-(h...)copy SMILEScopy InChI
Affinity DataIC50: 6.20E+4nMAssay Description:Inhibitory activity against CDK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FXVPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50181532(CHEMBL201307 | N-(3-fluorophenyl)-2-(2-(7-(3-(4-(h...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against p38-alpha MAPKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FXVPubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50181532(CHEMBL201307 | N-(3-fluorophenyl)-2-(2-(7-(3-(4-(h...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against JNK1alphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FXVPubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha/beta/gamma(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50181532(CHEMBL201307 | N-(3-fluorophenyl)-2-(2-(7-(3-(4-(h...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against PKAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FXVPubMed