Compile Data Set for Download or QSAR
Found 126 Enz. Inhib. hit(s) with all data for entry = 50037668
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM4566(4-anilinoquinazoline deriv. 1 | CHEMBL91867 | N-{4...)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibition of erbB1 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X96PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50182693(CHEMBL203644 | N-[4-[(3-chloro-4-fluorophenyl)amin...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Inhibition of erbB1 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X96PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50182684(CHEMBL437890 | N-[4-[(3-bromo-4-fluorophenyl)amino...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of erbB2 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X96PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50182688(CHEMBL204638 | N-[4-[(3-bromo-4-fluorophenyl)amino...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of HER stimulated human erbB autophosphorylation in MDA-MB-453 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X96PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50182697(CHEMBL203599 | N-[4-[(3-chloro-4-fluorophenyl)amin...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of erbB1 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X96PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50182693(CHEMBL203644 | N-[4-[(3-chloro-4-fluorophenyl)amin...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of erbB4 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X96PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of erbB1 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50182689(CHEMBL378144 | N-[4-[(3-bromophenyl)amino]pyrido[3...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of erbB1 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X96PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50182688(CHEMBL204638 | N-[4-[(3-bromo-4-fluorophenyl)amino...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Inhibition of erbB2 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X96PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50182697(CHEMBL203599 | N-[4-[(3-chloro-4-fluorophenyl)amin...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Inhibition of erbB2 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X96PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50182697(CHEMBL203599 | N-[4-[(3-chloro-4-fluorophenyl)amin...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Inhibition of ligand stimulated erbB2 autophosphorylation in T24 NIH cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X96PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50182684(CHEMBL437890 | N-[4-[(3-bromo-4-fluorophenyl)amino...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Inhibition of erbB4 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X96PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50182682(CHEMBL203661 | N-[4-[(3-chloro-4-fluorophenyl)amin...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Inhibition of erbB2 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X96PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50182678(CHEMBL205059 | N-[4-[(3-chloro-4-fluorophenyl)amin...)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Inhibition of erbB1 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X96PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50182697(CHEMBL203599 | N-[4-[(3-chloro-4-fluorophenyl)amin...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of HER stimulated human erbB autophosphorylation in MDA-MB-453 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X96PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50182688(CHEMBL204638 | N-[4-[(3-bromo-4-fluorophenyl)amino...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of erbB4 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X96PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50182682(CHEMBL203661 | N-[4-[(3-chloro-4-fluorophenyl)amin...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of erbB4 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X96PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50182684(CHEMBL437890 | N-[4-[(3-bromo-4-fluorophenyl)amino...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of erbB1 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X96PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50182693(CHEMBL203644 | N-[4-[(3-chloro-4-fluorophenyl)amin...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of erbB2 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X96PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50182697(CHEMBL203599 | N-[4-[(3-chloro-4-fluorophenyl)amin...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibition of erbB4 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X96PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50182682(CHEMBL203661 | N-[4-[(3-chloro-4-fluorophenyl)amin...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibition of erbB1 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X96PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50182690(CHEMBL202411 | N-[4-[(3-Chloro-4-fluorophenyl)amin...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of erbB1 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X96PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50182688(CHEMBL204638 | N-[4-[(3-bromo-4-fluorophenyl)amino...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibition of erbB1 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X96PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50182695(CHEMBL202360 | N-[4-[(3-bromophenyl)amino]-6-quina...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of erbB1 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X96PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50182695(CHEMBL202360 | N-[4-[(3-bromophenyl)amino]-6-quina...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of erbB4 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X96PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50182687(CHEMBL203645 | N-[4-[(3-chloro-4-fluorophenyl)amin...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of erbB1 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X96PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50182698(CHEMBL204085 | N-[4-[(3-chloro-4-fluorophenyl)amin...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of erbB1 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X96PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM4779(CHEMBL31965 | CHEMBL545315 | CI-1033 | Canertinib ...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of EGF stimulated human erbB1 autophosphorylation in NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X96PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50182682(CHEMBL203661 | N-[4-[(3-chloro-4-fluorophenyl)amin...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of EGF stimulated human erbB1 autophosphorylation in NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X96PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50182678(CHEMBL205059 | N-[4-[(3-chloro-4-fluorophenyl)amin...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of erbB4 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X96PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50182686(CHEMBL382073 | N-[4-[(3-chloro-4-fluorophenyl)amin...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of erbB1 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X96PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50182697(CHEMBL203599 | N-[4-[(3-chloro-4-fluorophenyl)amin...)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Inhibition of EGF stimulated human erbB1 autophosphorylation in NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X96PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50182695(CHEMBL202360 | N-[4-[(3-bromophenyl)amino]-6-quina...)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Inhibition of erbB2 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X96PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50182678(CHEMBL205059 | N-[4-[(3-chloro-4-fluorophenyl)amin...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of HER stimulated human erbB autophosphorylation in MDA-MB-453 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X96PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50182678(CHEMBL205059 | N-[4-[(3-chloro-4-fluorophenyl)amin...)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:Inhibition of erbB2 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X96PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50182690(CHEMBL202411 | N-[4-[(3-Chloro-4-fluorophenyl)amin...)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:Inhibition of erbB2 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X96PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50182698(CHEMBL204085 | N-[4-[(3-chloro-4-fluorophenyl)amin...)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:Inhibition of erbB2 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X96PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50182689(CHEMBL378144 | N-[4-[(3-bromophenyl)amino]pyrido[3...)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Inhibition of erbB2 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X96PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50182687(CHEMBL203645 | N-[4-[(3-chloro-4-fluorophenyl)amin...)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Inhibition of erbB4 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X96PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM4566(4-anilinoquinazoline deriv. 1 | CHEMBL91867 | N-{4...)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibition of EGF stimulated human erbB1 autophosphorylation in NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X96PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50182693(CHEMBL203644 | N-[4-[(3-chloro-4-fluorophenyl)amin...)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibition of EGF stimulated human erbB1 autophosphorylation in NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X96PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50182686(CHEMBL382073 | N-[4-[(3-chloro-4-fluorophenyl)amin...)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Inhibition of erbB2 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X96PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50182684(CHEMBL437890 | N-[4-[(3-bromo-4-fluorophenyl)amino...)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:Inhibition of EGF stimulated human erbB1 autophosphorylation in NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X96PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50182695(CHEMBL202360 | N-[4-[(3-bromophenyl)amino]-6-quina...)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:Inhibition of EGF stimulated human erbB1 autophosphorylation in NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X96PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50182683(CHEMBL380669 | N-[4-[(3-chloro-4-fluorophenyl)amin...)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:Inhibition of erbB2 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X96PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM4779(CHEMBL31965 | CHEMBL545315 | CI-1033 | Canertinib ...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of erbB1 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X96PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50182677(CHEMBL202556 | N-[4-[(3-chloro-4-fluorophenyl)amin...)copy SMILEScopy InChI
Affinity DataIC50: 3.10nMAssay Description:Inhibition of erbB1 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X96PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)copy SMILEScopy InChI
Affinity DataIC50: 3.10nMAssay Description:Inhibition of erbB1 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50182680(CHEMBL373207 | N-[4-[(3-chloro-4-fluorophenyl)amin...)copy SMILEScopy InChI
Affinity DataIC50: 3.10nMAssay Description:Inhibition of erbB1 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X96PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50182684(CHEMBL437890 | N-[4-[(3-bromo-4-fluorophenyl)amino...)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:Inhibition of HER stimulated human erbB autophosphorylation in MDA-MB-453 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X96PubMed
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