Compile Data Set for Download or QSAR
Found 36 Enz. Inhib. hit(s) with all data for entry = 50037804
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM14775(3-(cyclopentyloxy)-N-(3,5-dichloropyridin-4-yl)-4-...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant PDE4DMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM14775(3-(cyclopentyloxy)-N-(3,5-dichloropyridin-4-yl)-4-...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant PDE4BMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM14775(3-(cyclopentyloxy)-N-(3,5-dichloropyridin-4-yl)-4-...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant PDE4AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K0753ZPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50202531(9-cyclopentyl-5,6-dihydro-7-ethyl-3-(tert-butyl)-9...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of human recombinant PDE4BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K0753ZPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50202531(9-cyclopentyl-5,6-dihydro-7-ethyl-3-(tert-butyl)-9...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant PDE4DMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K0753ZPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50202531(9-cyclopentyl-5,6-dihydro-7-ethyl-3-(tert-butyl)-9...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant PDE4AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K0753ZPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50202544(9-cyclopentyl-5,6-dihydro-7-ethyl-3-(2-chloropheny...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant PDE4DMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K0753ZPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50202528(8-Cyclopentyl-6-ethyl-3-thiophen-2-yl-5,8-dihydro-...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant PDE4BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K0753ZPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50202528(8-Cyclopentyl-6-ethyl-3-thiophen-2-yl-5,8-dihydro-...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant PDE4DMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K0753ZPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM14775(3-(cyclopentyloxy)-N-(3,5-dichloropyridin-4-yl)-4-...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant PDE4CMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50202544(9-cyclopentyl-5,6-dihydro-7-ethyl-3-(2-chloropheny...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant PDE4BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K0753ZPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50202528(8-Cyclopentyl-6-ethyl-3-thiophen-2-yl-5,8-dihydro-...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of human recombinant PDE4AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K0753ZPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50202544(9-cyclopentyl-5,6-dihydro-7-ethyl-3-(2-chloropheny...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of human recombinant PDE4AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K0753ZPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50346088((1r,4r)-4-cyano-4-(3-(cyclopentyloxy)-4-methoxyphe...)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Inhibition of human recombinant PDE4DMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50202531(9-cyclopentyl-5,6-dihydro-7-ethyl-3-(tert-butyl)-9...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant PDE4CMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K0753ZPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50202530(9-cyclopentyl-5,6-dihydro-7-ethyl-3-(3-pyridyl)-9H...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant PDE4DMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K0753ZPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50202544(9-cyclopentyl-5,6-dihydro-7-ethyl-3-(2-chloropheny...)copy SMILEScopy InChI
Affinity DataIC50: 77nMAssay Description:Inhibition of human recombinant PDE4CMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K0753ZPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50346088((1r,4r)-4-cyano-4-(3-(cyclopentyloxy)-4-methoxyphe...)copy SMILEScopy InChI
Affinity DataIC50: 84nMAssay Description:Inhibition of human recombinant PDE4BMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50202528(8-Cyclopentyl-6-ethyl-3-thiophen-2-yl-5,8-dihydro-...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant PDE4CMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K0753ZPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50346088((1r,4r)-4-cyano-4-(3-(cyclopentyloxy)-4-methoxyphe...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of human recombinant PDE4AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K0753ZPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50042058((-)-rolipram | (4R)-4-[3-(cyclopentyloxy)-4-methox...)copy SMILEScopy InChI
Affinity DataIC50: 162nMAssay Description:Inhibition of human recombinant PDE4AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K0753ZPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50202532(9-cyclopentyl-5,6-dihydro-7-ethyl-3-(3-methoxyphen...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of human recombinant PDE4DMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K0753ZPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50202530(9-cyclopentyl-5,6-dihydro-7-ethyl-3-(3-pyridyl)-9H...)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:Inhibition of human recombinant PDE4BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K0753ZPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50042058((-)-rolipram | (4R)-4-[3-(cyclopentyloxy)-4-methox...)copy SMILEScopy InChI
Affinity DataIC50: 231nMAssay Description:Inhibition of human recombinant PDE4BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K0753ZPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50202530(9-cyclopentyl-5,6-dihydro-7-ethyl-3-(3-pyridyl)-9H...)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Inhibition of human recombinant PDE4AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K0753ZPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50202532(9-cyclopentyl-5,6-dihydro-7-ethyl-3-(3-methoxyphen...)copy SMILEScopy InChI
Affinity DataIC50: 430nMAssay Description:Inhibition of human recombinant PDE4BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K0753ZPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50346088((1r,4r)-4-cyano-4-(3-(cyclopentyloxy)-4-methoxyphe...)copy SMILEScopy InChI
Affinity DataIC50: 610nMAssay Description:Inhibition of human recombinant PDE4CMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50042058((-)-rolipram | (4R)-4-[3-(cyclopentyloxy)-4-methox...)copy SMILEScopy InChI
Affinity DataIC50: 622nMAssay Description:Inhibition of human recombinant PDE4DMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K0753ZPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50202530(9-cyclopentyl-5,6-dihydro-7-ethyl-3-(3-pyridyl)-9H...)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:Inhibition of human recombinant PDE4CMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K0753ZPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50202532(9-cyclopentyl-5,6-dihydro-7-ethyl-3-(3-methoxyphen...)copy SMILEScopy InChI
Affinity DataIC50: 770nMAssay Description:Inhibition of human recombinant PDE4AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K0753ZPubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50202528(8-Cyclopentyl-6-ethyl-3-thiophen-2-yl-5,8-dihydro-...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K0753ZPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50202532(9-cyclopentyl-5,6-dihydro-7-ethyl-3-(3-methoxyphen...)copy SMILEScopy InChI
Affinity DataIC50: 2.44E+3nMAssay Description:Inhibition of human recombinant PDE4CMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K0753ZPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50042058((-)-rolipram | (4R)-4-[3-(cyclopentyloxy)-4-methox...)copy SMILEScopy InChI
Affinity DataIC50: 3.69E+3nMAssay Description:Inhibition of human recombinant PDE4CMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K0753ZPubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50202528(8-Cyclopentyl-6-ethyl-3-thiophen-2-yl-5,8-dihydro-...)copy SMILEScopy InChI
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K0753ZPubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50202528(8-Cyclopentyl-6-ethyl-3-thiophen-2-yl-5,8-dihydro-...)copy SMILEScopy InChI
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K0753ZPubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50202528(8-Cyclopentyl-6-ethyl-3-thiophen-2-yl-5,8-dihydro-...)copy SMILEScopy InChI
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K0753ZPubMed