Compile Data Set for Download or QSAR
Found 21 Enz. Inhib. hit(s) with all data for entry = 50037928
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Instituto Superior T£cnico

Curated by ChEMBL
LigandPNGBDBM8465((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant MMP9More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26ZZXPubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Instituto Superior T£cnico

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of DHFR using dihydrofolic acid substrateMore data for this Ligand-Target Pair
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Instituto Superior T£cnico

Curated by ChEMBL
LigandPNGBDBM8465((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of human recombinant MMP14More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26ZZXPubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Instituto Superior T£cnico

Curated by ChEMBL
LigandPNGBDBM8465((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of human recombinant MMP2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26ZZXPubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Instituto Superior T£cnico

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of DHFR using folic acid substrateMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Homo sapiens (Human))
Instituto Superior T£cnico

Curated by ChEMBL
LigandPNGBDBM50199731(CHEMBL244883 | methotrexate gamma-hydroxamic acid)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of DHFR using dihydrofolic acid substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26ZZXPubMed
TargetMatrilysin(Homo sapiens (Human))
Instituto Superior T£cnico

Curated by ChEMBL
LigandPNGBDBM8465((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant MMP7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26ZZXPubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Instituto Superior T£cnico

Curated by ChEMBL
LigandPNGBDBM50199735(CHEMBL388879 | methotrexate gamma-L-proline-hydrox...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of DHFR using dihydrofolic acid substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26ZZXPubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Instituto Superior T£cnico

Curated by ChEMBL
LigandPNGBDBM50199735(CHEMBL388879 | methotrexate gamma-L-proline-hydrox...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of DHFR using folic acid substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26ZZXPubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Instituto Superior T£cnico

Curated by ChEMBL
LigandPNGBDBM50199733(CHEMBL396296 | methotrexate gamma-L-phenylalanineh...)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Inhibition of DHFR using dihydrofolic acid substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26ZZXPubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Instituto Superior T£cnico

Curated by ChEMBL
LigandPNGBDBM50199731(CHEMBL244883 | methotrexate gamma-hydroxamic acid)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Inhibition of DHFR using folic acid substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26ZZXPubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Instituto Superior T£cnico

Curated by ChEMBL
LigandPNGBDBM50199733(CHEMBL396296 | methotrexate gamma-L-phenylalanineh...)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Inhibition of DHFR using folic acid substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26ZZXPubMed
TargetMatrilysin(Homo sapiens (Human))
Instituto Superior T£cnico

Curated by ChEMBL
LigandPNGBDBM50199734(CHEMBL267603 | folate gamma-L-phenylalaninehydroxa...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human recombinant MMP7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26ZZXPubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Instituto Superior T£cnico

Curated by ChEMBL
LigandPNGBDBM50199733(CHEMBL396296 | methotrexate gamma-L-phenylalanineh...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human recombinant MMP9More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26ZZXPubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Instituto Superior T£cnico

Curated by ChEMBL
LigandPNGBDBM50199734(CHEMBL267603 | folate gamma-L-phenylalaninehydroxa...)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of human recombinant MMP9More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26ZZXPubMed
TargetMatrilysin(Homo sapiens (Human))
Instituto Superior T£cnico

Curated by ChEMBL
LigandPNGBDBM50199733(CHEMBL396296 | methotrexate gamma-L-phenylalanineh...)copy SMILEScopy InChI
Affinity DataIC50: 4.40E+4nMAssay Description:Inhibition of human recombinant MMP7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26ZZXPubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Instituto Superior T£cnico

Curated by ChEMBL
LigandPNGBDBM50199733(CHEMBL396296 | methotrexate gamma-L-phenylalanineh...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of human recombinant MMP2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26ZZXPubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Instituto Superior T£cnico

Curated by ChEMBL
LigandPNGBDBM50199734(CHEMBL267603 | folate gamma-L-phenylalaninehydroxa...)copy SMILEScopy InChI
Affinity DataIC50: 6.50E+4nMAssay Description:Inhibition of human recombinant MMP2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26ZZXPubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Instituto Superior T£cnico

Curated by ChEMBL
LigandPNGBDBM50199733(CHEMBL396296 | methotrexate gamma-L-phenylalanineh...)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibition of human recombinant MMP14More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26ZZXPubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Instituto Superior T£cnico

Curated by ChEMBL
LigandPNGBDBM50199734(CHEMBL267603 | folate gamma-L-phenylalaninehydroxa...)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of human recombinant MMP14More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26ZZXPubMed
TargetMatrilysin(Homo sapiens (Human))
Instituto Superior T£cnico

Curated by ChEMBL
LigandPNGBDBM50199731(CHEMBL244883 | methotrexate gamma-hydroxamic acid)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MMP7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26ZZXPubMed