Compile Data Set for Download or QSAR
Found 54 Enz. Inhib. hit(s) with all data for entry = 50038175
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM14949(2-aminoquinazoline 5 | 3-(2-aminoquinazolin-6-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibition of Lck by HTRF assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50372706(CHEMBL257858)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of Lck by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41FKPubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM14949(2-aminoquinazoline 5 | 3-(2-aminoquinazolin-6-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41FKPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM14949(2-aminoquinazoline 5 | 3-(2-aminoquinazolin-6-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41FKPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50372708(CHEMBL269936)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41FKPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM14949(2-aminoquinazoline 5 | 3-(2-aminoquinazolin-6-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41FKPubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50372710(CHEMBL255533)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of Lck by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41FKPubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50372714(CHEMBL255989)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of Lck by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41FKPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM14949(2-aminoquinazoline 5 | 3-(2-aminoquinazolin-6-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of Jak3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41FKPubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50372711(CHEMBL270793)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of Lck by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41FKPubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50372712(CHEMBL271099)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of Lck by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41FKPubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50372707(CHEMBL408292)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of Lck by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41FKPubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50372715(CHEMBL271101)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Inhibition of Lck by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41FKPubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50372713(CHEMBL255132)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Inhibition of Lck by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41FKPubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50372716(CHEMBL271018)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:Inhibition of Lck by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41FKPubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50372708(CHEMBL269936)copy SMILEScopy InChI
Affinity DataIC50: 84nMAssay Description:Inhibition of Lck by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41FKPubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50372709(CHEMBL271650)copy SMILEScopy InChI
Affinity DataIC50: 101nMAssay Description:Inhibition of Lck by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41FKPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50372710(CHEMBL255533)copy SMILEScopy InChI
Affinity DataIC50: 254nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41FKPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50372706(CHEMBL257858)copy SMILEScopy InChI
Affinity DataIC50: 255nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41FKPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50372706(CHEMBL257858)copy SMILEScopy InChI
Affinity DataIC50: 334nMAssay Description:Inhibition of Jak3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41FKPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50372706(CHEMBL257858)copy SMILEScopy InChI
Affinity DataIC50: 856nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41FKPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50372711(CHEMBL270793)copy SMILEScopy InChI
Affinity DataIC50: 2.03E+3nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41FKPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50372716(CHEMBL271018)copy SMILEScopy InChI
Affinity DataIC50: 2.72E+3nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41FKPubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50372706(CHEMBL257858)copy SMILEScopy InChI
Affinity DataIC50: 3.44E+3nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41FKPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50372708(CHEMBL269936)copy SMILEScopy InChI
Affinity DataIC50: 6.68E+3nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41FKPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50372716(CHEMBL271018)copy SMILEScopy InChI
Affinity DataIC50: 8.33E+3nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41FKPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50372715(CHEMBL271101)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41FKPubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50372710(CHEMBL255533)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41FKPubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50372715(CHEMBL271101)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41FKPubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50372707(CHEMBL408292)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41FKPubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50372709(CHEMBL271650)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41FKPubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50372714(CHEMBL255989)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41FKPubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50372713(CHEMBL255132)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41FKPubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50372708(CHEMBL269936)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41FKPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50372715(CHEMBL271101)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of Jak3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41FKPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50372712(CHEMBL271099)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of Jak3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41FKPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50372707(CHEMBL408292)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of Jak3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41FKPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50372711(CHEMBL270793)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of Jak3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41FKPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50372714(CHEMBL255989)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of Jak3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41FKPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50372713(CHEMBL255132)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of Jak3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41FKPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50372715(CHEMBL271101)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41FKPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50372712(CHEMBL271099)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41FKPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50372709(CHEMBL271650)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41FKPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50372714(CHEMBL255989)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41FKPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50372713(CHEMBL255132)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41FKPubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50372716(CHEMBL271018)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41FKPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50372716(CHEMBL271018)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of Jak3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41FKPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50372710(CHEMBL255533)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41FKPubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50372712(CHEMBL271099)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41FKPubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50372711(CHEMBL270793)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41FKPubMed
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