Compile Data Set for Download or QSAR
Found 33 Enz. Inhib. hit(s) with all data for entry = 50038458
TargetPhosphotransferase(Trypanosoma cruzi)
Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL
LigandPNGBDBM50173799((3-bromo-phenyl)-aminomethylene-1,1-bisphosphonate...)copy SMILEScopy InChI
Affinity DataKi:  400nMAssay Description:Inhibition of Trypanosoma cruzi hexokinase in presence of D-glucose, 1 mM ATP and 3 mM MgCl2 by competitive inhibition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MXHPubMed
TargetPhosphotransferase(Trypanosoma cruzi)
Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL
LigandPNGBDBM50180152((9-ethyl-9H-3-carbazolyl)-aminomethylene-1,1-bisph...)copy SMILEScopy InChI
Affinity DataKi:  500nMAssay Description:Inhibition of Trypanosoma cruzi hexokinase in presence of D-glucose, 1 mM ATP and 3 mM MgCl2 by competitive inhibition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MXHPubMed
TargetPhosphotransferase(Trypanosoma cruzi)
Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL
LigandPNGBDBM50173799((3-bromo-phenyl)-aminomethylene-1,1-bisphosphonate...)copy SMILEScopy InChI
Affinity DataKi:  600nMAssay Description:Inhibition of Trypanosoma cruzi hexokinase in presence of ATP, 2 mM D-glucose and 3 mM MgCl2 by competitive inhibition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MXHPubMed
TargetPhosphotransferase(Trypanosoma cruzi)
Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL
LigandPNGBDBM50173799((3-bromo-phenyl)-aminomethylene-1,1-bisphosphonate...)copy SMILEScopy InChI
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of Trypanosoma cruzi hexokinase in presence of ATP, 2 mM D-glucose and 3 mM MgCl2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MXHPubMed
TargetPhosphotransferase(Trypanosoma cruzi)
Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL
LigandPNGBDBM50180152((9-ethyl-9H-3-carbazolyl)-aminomethylene-1,1-bisph...)copy SMILEScopy InChI
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of glycosomal Trypanosoma cruzi hexokinase in presence of ATP, 2 mM D-glucose and 3 mM MgCl2 by competitive inhibition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MXHPubMed
TargetPhosphotransferase(Trypanosoma cruzi)
Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL
LigandPNGBDBM50180152((9-ethyl-9H-3-carbazolyl)-aminomethylene-1,1-bisph...)copy SMILEScopy InChI
Affinity DataKi:  1.70E+3nMAssay Description:Inhibition of glycosomal Trypanosoma cruzi hexokinase in presence of ATP, 2 mM D-glucose and 3 mM MgCl2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MXHPubMed
TargetPhosphotransferase(Trypanosoma cruzi)
Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL
LigandPNGBDBM50180152((9-ethyl-9H-3-carbazolyl)-aminomethylene-1,1-bisph...)copy SMILEScopy InChI
Affinity DataKi:  1.70E+3nMAssay Description:Inhibition of Trypanosoma cruzi hexokinase in presence of ATP, 2 mM D-glucose and 3 mM MgCl2 by competitive inhibition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MXHPubMed
TargetPhosphotransferase(Trypanosoma cruzi)
Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL
LigandPNGBDBM50180152((9-ethyl-9H-3-carbazolyl)-aminomethylene-1,1-bisph...)copy SMILEScopy InChI
Affinity DataKi:  2.40E+3nMAssay Description:Inhibition of glycosomal Trypanosoma cruzi hexokinase in presence of D-glucose, 1 mM ATP and 3 mM MgCl2 by competitive inhibition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MXHPubMed
TargetPhosphotransferase(Trypanosoma cruzi)
Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL
LigandPNGBDBM50173799((3-bromo-phenyl)-aminomethylene-1,1-bisphosphonate...)copy SMILEScopy InChI
Affinity DataKi:  2.60E+3nMAssay Description:Inhibition of glycosomal Trypanosoma cruzi hexokinase in presence of ATP, 2 mM D-glucose and 3 mM MgCl2 by competitive inhibition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MXHPubMed
TargetPhosphotransferase(Trypanosoma cruzi)
Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL
LigandPNGBDBM50180152((9-ethyl-9H-3-carbazolyl)-aminomethylene-1,1-bisph...)copy SMILEScopy InChI
Affinity DataKi:  2.80E+3nMAssay Description:Inhibition of Trypanosoma cruzi hexokinase in presence of ATP, 2 mM D-glucose and 3 mM MgCl2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MXHPubMed
TargetPhosphotransferase(Trypanosoma cruzi)
Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL
LigandPNGBDBM50098386((1-hydroxy-1-phosphono-2-pyridin-4-yl-ethyl)-phosp...)copy SMILEScopy InChI
Affinity DataKi:  2.80E+3nMAssay Description:Inhibition of Trypanosoma cruzi hexokinase in presence of ATP, 2 mM D-glucose and 3 mM MgCl2 by competitive inhibition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MXHPubMed
TargetPhosphotransferase(Trypanosoma cruzi)
Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL
LigandPNGBDBM50173799((3-bromo-phenyl)-aminomethylene-1,1-bisphosphonate...)copy SMILEScopy InChI
Affinity DataKi:  2.90E+3nMAssay Description:Inhibition of glycosomal Trypanosoma cruzi hexokinase in presence of D-glucose, 1 mM ATP and 3 mM MgCl2 by competitive inhibition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MXHPubMed
TargetPhosphotransferase(Trypanosoma cruzi)
Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL
LigandPNGBDBM50098386((1-hydroxy-1-phosphono-2-pyridin-4-yl-ethyl)-phosp...)copy SMILEScopy InChI
Affinity DataKi:  3.30E+3nMAssay Description:Inhibition of Trypanosoma cruzi hexokinase in presence of D-glucose, 1 mM ATP and 3 mM MgCl2 by competitive inhibition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MXHPubMed
TargetPhosphotransferase(Trypanosoma cruzi)
Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL
LigandPNGBDBM50098386((1-hydroxy-1-phosphono-2-pyridin-4-yl-ethyl)-phosp...)copy SMILEScopy InChI
Affinity DataKi:  3.40E+3nMAssay Description:Inhibition of glycosomal Trypanosoma cruzi hexokinase in presence of D-glucose, 1 mM ATP and 3 mM MgCl2 by competitive inhibition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MXHPubMed
TargetPhosphotransferase(Trypanosoma cruzi)
Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL
LigandPNGBDBM50180152((9-ethyl-9H-3-carbazolyl)-aminomethylene-1,1-bisph...)copy SMILEScopy InChI
Affinity DataKi:  4.30E+3nMAssay Description:Inhibition of glycosomal Trypanosoma cruzi hexokinase in presence of D-glucose, 1 mM ATP and 3 mM MgCl2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MXHPubMed
TargetPhosphotransferase(Trypanosoma cruzi)
Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL
LigandPNGBDBM50098386((1-hydroxy-1-phosphono-2-pyridin-4-yl-ethyl)-phosp...)copy SMILEScopy InChI
Affinity DataKi:  4.30E+3nMAssay Description:Inhibition of Trypanosoma cruzi hexokinase in presence of ATP, 2 mM D-glucose and 3 mM MgCl2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MXHPubMed
TargetPhosphotransferase(Trypanosoma cruzi)
Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL
LigandPNGBDBM50098386((1-hydroxy-1-phosphono-2-pyridin-4-yl-ethyl)-phosp...)copy SMILEScopy InChI
Affinity DataKi:  6.00E+3nMAssay Description:Inhibition of Trypanosoma cruzi hexokinase in presence of D-glucose, 1 mM ATP and 3 mM MgCl2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MXHPubMed
TargetPhosphotransferase(Trypanosoma cruzi)
Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL
LigandPNGBDBM50098386((1-hydroxy-1-phosphono-2-pyridin-4-yl-ethyl)-phosp...)copy SMILEScopy InChI
Affinity DataKi:  1.05E+4nMAssay Description:Inhibition of glycosomal Trypanosoma cruzi hexokinase in presence of ATP, 2 mM D-glucose and 3 mM MgCl2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MXHPubMed
TargetPhosphotransferase(Trypanosoma cruzi)
Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL
LigandPNGBDBM50173799((3-bromo-phenyl)-aminomethylene-1,1-bisphosphonate...)copy SMILEScopy InChI
Affinity DataKi:  1.06E+4nMAssay Description:Inhibition of glycosomal Trypanosoma cruzi hexokinase in presence of D-glucose, 1 mM ATP and 3 mM MgCl2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MXHPubMed
TargetPhosphotransferase(Trypanosoma cruzi)
Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL
LigandPNGBDBM50098386((1-hydroxy-1-phosphono-2-pyridin-4-yl-ethyl)-phosp...)copy SMILEScopy InChI
Affinity DataKi:  1.14E+4nMAssay Description:Inhibition of glycosomal Trypanosoma cruzi hexokinase in presence of ATP, 2 mM D-glucose and 3 mM MgCl2 by competitive inhibition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MXHPubMed
TargetPhosphotransferase(Trypanosoma cruzi)
Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL
LigandPNGBDBM50098386((1-hydroxy-1-phosphono-2-pyridin-4-yl-ethyl)-phosp...)copy SMILEScopy InChI
Affinity DataKi:  4.39E+4nMAssay Description:Inhibition of glycosomal Trypanosoma cruzi hexokinase in presence of D-glucose, 1 mM ATP and 3 mM MgCl2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MXHPubMed
TargetPhosphotransferase(Trypanosoma cruzi)
Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL
LigandPNGBDBM50138040((biphenyl-3-ylamino)methylenediphosphonic acid | B...)copy SMILEScopy InChI
Affinity DataIC50: 810nMAssay Description:Inhibition of Trypanosoma cruzi hexokinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MXHPubMed
TargetPhosphotransferase(Trypanosoma cruzi)
Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL
LigandPNGBDBM50173796(CHEMBL450938 | [(3-nitro-phenylamino)-phosphono-me...)copy SMILEScopy InChI
Affinity DataIC50: 810nMAssay Description:Inhibition of Trypanosoma cruzi hexokinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MXHPubMed
TargetPhosphotransferase(Trypanosoma cruzi)
Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL
LigandPNGBDBM50173787((3-(hydroxymethyl)phenylamino)methylenediphosphoni...)copy SMILEScopy InChI
Affinity DataIC50: 810nMAssay Description:Inhibition of Trypanosoma cruzi hexokinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MXHPubMed
TargetPhosphotransferase(Trypanosoma cruzi)
Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL
LigandPNGBDBM50173794((3',4'-difluorobiphenyl-3-ylamino)methylenediphosp...)copy SMILEScopy InChI
Affinity DataIC50: 810nMAssay Description:Inhibition of Trypanosoma cruzi hexokinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MXHPubMed
TargetPhosphotransferase(Trypanosoma cruzi)
Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL
LigandPNGBDBM50138049((4-heptylphenylamino)methylenediphosphonic acid | ...)copy SMILEScopy InChI
Affinity DataIC50: 810nMAssay Description:Inhibition of Trypanosoma cruzi hexokinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MXHPubMed
TargetPhosphotransferase(Trypanosoma cruzi)
Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL
LigandPNGBDBM50180152((9-ethyl-9H-3-carbazolyl)-aminomethylene-1,1-bisph...)copy SMILEScopy InChI
Affinity DataIC50: 810nMAssay Description:Inhibition of Trypanosoma cruzi hexokinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MXHPubMed
TargetPhosphotransferase(Trypanosoma cruzi)
Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL
LigandPNGBDBM50173768((biphenyl-3-yl-hydroxy-phosphono-methyl)-phosphoni...)copy SMILEScopy InChI
Affinity DataIC50: 810nMAssay Description:Inhibition of Trypanosoma cruzi hexokinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MXHPubMed
TargetPhosphotransferase(Trypanosoma cruzi)
Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL
LigandPNGBDBM50173790(2-(biphenyl-3-ylamino)ethane-1,1-diyldiphosphonic ...)copy SMILEScopy InChI
Affinity DataIC50: 810nMAssay Description:Inhibition of Trypanosoma cruzi hexokinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MXHPubMed
TargetPhosphotransferase(Trypanosoma cruzi)
Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL
LigandPNGBDBM25269((1-hydroxy-1-phosphonodecyl)phosphonic acid | CHEM...)copy SMILEScopy InChI
Affinity DataIC50: 810nMAssay Description:Inhibition of Trypanosoma cruzi hexokinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MXHPubMed
TargetPhosphotransferase(Trypanosoma cruzi)
Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL
LigandPNGBDBM50173752((3-(methoxymethyl)phenylamino)methylenediphosphoni...)copy SMILEScopy InChI
Affinity DataIC50: 810nMAssay Description:Inhibition of Trypanosoma cruzi hexokinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MXHPubMed
TargetPhosphotransferase(Trypanosoma cruzi)
Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL
LigandPNGBDBM50173799((3-bromo-phenyl)-aminomethylene-1,1-bisphosphonate...)copy SMILEScopy InChI
Affinity DataIC50: 950nMAssay Description:Inhibition of Trypanosoma cruzi hexokinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MXHPubMed
TargetPhosphotransferase(Trypanosoma cruzi)
Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL
LigandPNGBDBM50098386((1-hydroxy-1-phosphono-2-pyridin-4-yl-ethyl)-phosp...)copy SMILEScopy InChI
Affinity DataIC50: 1.27E+4nMAssay Description:Inhibition of Trypanosoma cruzi hexokinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MXHPubMed