Compile Data Set for Download or QSAR
Found 14 Enz. Inhib. hit(s) with all data for entry = 50038599
TargetHistone deacetylase 3(Homo sapiens (Human))
Istituto di Ricerche di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM19428((2E)-N-hydroxy-3-(4-{[(2-hydroxyethyl)[2-(1H-indol...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of flag-tagged HDAC3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82B5XPubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Istituto di Ricerche di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50238632((6S,9S,12S,14aR)-6-((S)-sec-Butyl)-9-(1-methoxy-1H...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of flag-tagged HDAC4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82B5XPubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Istituto di Ricerche di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM19428((2E)-N-hydroxy-3-(4-{[(2-hydroxyethyl)[2-(1H-indol...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of flag-tagged HDAC4 by Biomol assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82B5XPubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Istituto di Ricerche di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50238632((6S,9S,12S,14aR)-6-((S)-sec-Butyl)-9-(1-methoxy-1H...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibition of flag-tagged HDAC4 by Biomol assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82B5XPubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Istituto di Ricerche di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM19428((2E)-N-hydroxy-3-(4-{[(2-hydroxyethyl)[2-(1H-indol...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibition of flag-tagged HDAC4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82B5XPubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Istituto di Ricerche di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50238632((6S,9S,12S,14aR)-6-((S)-sec-Butyl)-9-(1-methoxy-1H...)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Inhibition of flag-tagged HDAC4 by pull-down assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82B5XPubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Istituto di Ricerche di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50238632((6S,9S,12S,14aR)-6-((S)-sec-Butyl)-9-(1-methoxy-1H...)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibition of flag-tagged HDAC3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82B5XPubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Istituto di Ricerche di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM19428((2E)-N-hydroxy-3-(4-{[(2-hydroxyethyl)[2-(1H-indol...)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibition of HDAC4 catalytic domain expressed in HEK293 cells by Biomol assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82B5XPubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Istituto di Ricerche di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM19428((2E)-N-hydroxy-3-(4-{[(2-hydroxyethyl)[2-(1H-indol...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of flag-tagged HDAC4 expressed in HEK293 cells by Biomol assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82B5XPubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Istituto di Ricerche di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM19428((2E)-N-hydroxy-3-(4-{[(2-hydroxyethyl)[2-(1H-indol...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of flag-tagged HDAC4 by pull-down assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82B5XPubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Istituto di Ricerche di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50377931(CHEMBL1791402)copy SMILEScopy InChI
Affinity DataIC50: 88nMAssay Description:Inhibition of flag-tagged HDAC4 by Biomol assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82B5XPubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Istituto di Ricerche di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50377931(CHEMBL1791402)copy SMILEScopy InChI
Affinity DataIC50: 152nMAssay Description:Inhibition of flag-tagged HDAC4 by pull-down assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82B5XPubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Istituto di Ricerche di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM19410(CHEMBL27759 | MS-275 | US11377423, MS-275 | US1167...)copy SMILEScopy InChI
Affinity DataIC50: 510nMAssay Description:Inhibition of flag-tagged HDAC4 by pull-down assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82B5XPubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Istituto di Ricerche di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM19410(CHEMBL27759 | MS-275 | US11377423, MS-275 | US1167...)copy SMILEScopy InChI
Affinity DataIC50: 3.02E+3nMAssay Description:Inhibition of flag-tagged HDAC4 by Biomol assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82B5XPubMed