Compile Data Set for Download or QSAR
Found 14 Enz. Inhib. hit(s) with all data for entry = 50038677
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50243238(({2-Bromo-4-[40-bromo-30-(difluorosulfamoylmethyl)...)copy SMILEScopy InChI
Affinity DataKi:  24nMAssay Description:Inhibition of human PTP1B expressed in Escherichia coli BL21(DE3) cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930V2PPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50243240((3-((R)-2-((S)-2-((S)-2-((S)-2-((S)-2-amino-3-carb...)copy SMILEScopy InChI
Affinity DataKi:  24nMAssay Description:Inhibition of human PTP1B expressed in Escherichia coli BL21(DE3) cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930V2PPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50243239({2-Bromo-4-[40-bromo-30-(difluorosulfamoylmethyl)b...)copy SMILEScopy InChI
Affinity DataKi:  3.30E+3nMAssay Description:Inhibition of human PTP1B expressed in Escherichia coli BL21(DE3) cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930V2PPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50243237([2-Bromo-4-(40-bromo-30-sulfamoylbiphenyl-4-ylmeth...)copy SMILEScopy InChI
Affinity DataKi:  1.03E+4nMAssay Description:Inhibition of human PTP1B expressed in Escherichia coli BL21(DE3) cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930V2PPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50243236([2-Bromo-4-(40-bromo-30-sulfamoylbiphenyl-4-ylmeth...)copy SMILEScopy InChI
Affinity DataKi:  1.06E+4nMAssay Description:Inhibition of human PTP1B expressed in Escherichia coli BL21(DE3) cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930V2PPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50243184({[2-Bromo-4-(40-bromo-30-sulfamoylbiphenyl-4-ylmet...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of human PTP1B expressed in Escherichia coli BL21(DE3) cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930V2PPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50243238(({2-Bromo-4-[40-bromo-30-(difluorosulfamoylmethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of human PTP1B expressed in Escherichia coli BL21(DE3) cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930V2PPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50243239({2-Bromo-4-[40-bromo-30-(difluorosulfamoylmethyl)b...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human PTP1B expressed in Escherichia coli BL21(DE3) cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930V2PPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50243241(CID44560696 | PTP1B inhibitor 3 | {3-[(2R)-2-[(2S)...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PTP1B expressed in Escherichia coli BL21(DE3) cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930V2PPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50243236([2-Bromo-4-(40-bromo-30-sulfamoylbiphenyl-4-ylmeth...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human PTP1B expressed in Escherichia coli BL21(DE3) cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930V2PPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50243237([2-Bromo-4-(40-bromo-30-sulfamoylbiphenyl-4-ylmeth...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of human PTP1B expressed in Escherichia coli BL21(DE3) cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930V2PPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50075312((Difluoro-naphthalen-2-yl-methyl)-phosphonic acid ...)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of human PTP1B expressed in Escherichia coli BL21(DE3) cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930V2PPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50243311((S)-4-((S)-2-((S)-2-((S)-2-amino-3-carboxypropanam...)copy SMILEScopy InChI
Affinity DataIC50: 4.40E+4nMAssay Description:Inhibition of human PTP1B expressed in Escherichia coli BL21(DE3) cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930V2PPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50072598(CHEMBL109646 | Sodium; difluoro-naphthalen-2-yl-me...)copy SMILEScopy InChI
Affinity DataIC50: 1.75E+5nMAssay Description:Inhibition of human PTP1B expressed in Escherichia coli BL21(DE3) cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930V2PPubMed