Compile Data Set for Download or QSAR
Found 38 Enz. Inhib. hit(s) with all data for entry = 50038691
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kissei Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50059889((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human Syk expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM887NPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kissei Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50249539(5-((1S,2R)-2-aminocyclohexylamino)-7-(3,5-dimethox...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human Syk expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM887NPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kissei Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50274673(CHEMBL485204 | cis-5-(2-Aminocyclohexylamino)-7-(3...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of human Syk expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM887NPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kissei Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50274756(CHEMBL459146 | cis-5-(2-Aminocyclohexylamino)-7-(3...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of human Syk expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM887NPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kissei Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50249254(5-((1S,2R)-2-aminocyclohexylamino)-7-(3,5-dimethox...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of human Syk expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM887NPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kissei Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50274757(5-((1S,2R)-2-Aminocyclohexylamino)-7-(3,5-dimethox...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of human Syk expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM887NPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kissei Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50274755(CHEMBL458973 | cis-5-(2-Aminocyclohexylamino)-7-(3...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of human Syk expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM887NPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kissei Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50274712(CHEMBL515054 | cis-5-(2-Aminocyclohexylamino)-7-(3...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of human Syk expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM887NPubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Kissei Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50274757(5-((1S,2R)-2-Aminocyclohexylamino)-7-(3,5-dimethox...)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of human ZAP70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM887NPubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Kissei Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50059889((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:Inhibition of human ZAP70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM887NPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kissei Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50274713(CHEMBL457519 | cis-5-(2-Aminocyclohexylamino)-7-(4...)copy SMILEScopy InChI
Affinity DataIC50: 92nMAssay Description:Inhibition of human Syk expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM887NPubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Kissei Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50249254(5-((1S,2R)-2-aminocyclohexylamino)-7-(3,5-dimethox...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of human ZAP70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM887NPubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Kissei Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50274758(5-(2-Amino-2-methylpropylamino)-7-(3,5-dimethoxyph...)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition of human ZAP70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM887NPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kissei Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM26404(5-[(2-aminoethyl)amino]-7-[(3,5-dimethoxyphenyl)am...)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:Inhibition of human Syk expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM887NPubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Kissei Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50274673(CHEMBL485204 | cis-5-(2-Aminocyclohexylamino)-7-(3...)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:Inhibition of human ZAP70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM887NPubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Kissei Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50249539(5-((1S,2R)-2-aminocyclohexylamino)-7-(3,5-dimethox...)copy SMILEScopy InChI
Affinity DataIC50: 330nMAssay Description:Inhibition of human ZAP70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM887NPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kissei Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50249509(5-((1R,2S)-2-Aminocyclohexylamino)-7-(3,5-dimethox...)copy SMILEScopy InChI
Affinity DataIC50: 380nMAssay Description:Inhibition of human Syk expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM887NPubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Kissei Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50274756(CHEMBL459146 | cis-5-(2-Aminocyclohexylamino)-7-(3...)copy SMILEScopy InChI
Affinity DataIC50: 480nMAssay Description:Inhibition of human ZAP70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM887NPubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Kissei Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50249509(5-((1R,2S)-2-Aminocyclohexylamino)-7-(3,5-dimethox...)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:Inhibition of human ZAP70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM887NPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kissei Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50274634(CHEMBL484350 | cis-7-(3,5-Dimethoxyphenylamino)-5-...)copy SMILEScopy InChI
Affinity DataIC50: 720nMAssay Description:Inhibition of human Syk expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM887NPubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Kissei Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50274755(CHEMBL458973 | cis-5-(2-Aminocyclohexylamino)-7-(3...)copy SMILEScopy InChI
Affinity DataIC50: 730nMAssay Description:Inhibition of human ZAP70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM887NPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kissei Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50274758(5-(2-Amino-2-methylpropylamino)-7-(3,5-dimethoxyph...)copy SMILEScopy InChI
Affinity DataIC50: 840nMAssay Description:Inhibition of human Syk expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM887NPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kissei Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50249224(7-(3,5-Dimethoxyphenylamino)-5-(2-methylcyclohexyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human Syk expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM887NPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kissei Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50274672(CHEMBL520842 | trans-5-(2-Aminocyclohexylamino)-7-...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human Syk expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM887NPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kissei Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50274633(5-(3-Aminopropylamino)-7-(3,5-dimethoxyphenylamino...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human Syk expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM887NPubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Kissei Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50274712(CHEMBL515054 | cis-5-(2-Aminocyclohexylamino)-7-(3...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human ZAP70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM887NPubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Kissei Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50274634(CHEMBL484350 | cis-7-(3,5-Dimethoxyphenylamino)-5-...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human ZAP70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM887NPubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Kissei Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM26403(7-[(3,5-dimethoxyphenyl)amino]-5-[(2-hydroxyethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human ZAP70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM887NPubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Kissei Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50249224(7-(3,5-Dimethoxyphenylamino)-5-(2-methylcyclohexyl...)copy SMILEScopy InChI
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of human ZAP70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM887NPubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Kissei Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM26404(5-[(2-aminoethyl)amino]-7-[(3,5-dimethoxyphenyl)am...)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of human ZAP70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM887NPubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Kissei Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50274713(CHEMBL457519 | cis-5-(2-Aminocyclohexylamino)-7-(4...)copy SMILEScopy InChI
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of human ZAP70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM887NPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kissei Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM26403(7-[(3,5-dimethoxyphenyl)amino]-5-[(2-hydroxyethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of human Syk expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM887NPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kissei Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM26402(5-amino-7-[(3,5-dimethoxyphenyl)amino]imidazo[1,2-...)copy SMILEScopy InChI
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of human Syk expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM887NPubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Kissei Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50274711(CHEMBL458788 | cis-5-(2-Aminocyclohexylamino)-7-(2...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ZAP70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM887NPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kissei Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50274711(CHEMBL458788 | cis-5-(2-Aminocyclohexylamino)-7-(2...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human Syk expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM887NPubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Kissei Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM26402(5-amino-7-[(3,5-dimethoxyphenyl)amino]imidazo[1,2-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ZAP70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM887NPubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Kissei Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50274672(CHEMBL520842 | trans-5-(2-Aminocyclohexylamino)-7-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ZAP70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM887NPubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Kissei Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50274633(5-(3-Aminopropylamino)-7-(3,5-dimethoxyphenylamino...)copy SMILEScopy InChI
Affinity DataIC50: 1.24E+4nMAssay Description:Inhibition of human ZAP70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM887NPubMed