Compile Data Set for Download or QSAR
Found 34 Enz. Inhib. hit(s) with all data for entry = 50038750
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50293015(CHEMBL502503 | Methyl 4-((4-(2-(6,7-Dimethoxy-1,2,...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of ABCG2 overexpressed in human MCF7/Topo cells by flow cytometric-based mitoxantrone efflux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PQ4PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50293016(CHEMBL453536 | Methyl 4-((4-(2-(6,7-dimethoxy-1,2,...)copy SMILEScopy InChI
Affinity DataIC50: 119nMAssay Description:Inhibition of ABCG2 overexpressed in human MCF7/Topo cells by flow cytometric-based mitoxantrone efflux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PQ4PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50293013(CHEMBL455275 | Methyl 4-((4-(2-(6,7-dimethoxy-1,2,...)copy SMILEScopy InChI
Affinity DataIC50: 179nMAssay Description:Inhibition of ABCG2 overexpressed in human MCF7/Topo cells by flow cytometric-based mitoxantrone efflux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PQ4PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50293014(CHEMBL506278 | Methyl 4-((4-(2-(6,7-dimethoxy-1,2,...)copy SMILEScopy InChI
Affinity DataIC50: 183nMAssay Description:Inhibition of ABCG2 overexpressed in human MCF7/Topo cells by flow cytometric-based mitoxantrone efflux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PQ4PubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50206310(5-Methoxy-9-oxo-9,10-dihydro-acridine-4-carboxylic...)copy SMILEScopy InChI
Affinity DataIC50: 193nMAssay Description:Inhibition of ABCB1 overexpressed in human KBv1 cells by flow cytometric-based calcein-AM efflux assayMore data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50075373(1N-{4-[2-(6,7-dimethoxy-1,2,3,4-tetrahydro-2-isoqu...)copy SMILEScopy InChI
Affinity DataIC50: 223nMAssay Description:Inhibition of ABCB1 overexpressed in human KBv1 cells by flow cytometric-based calcein-AM efflux assayMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50305083(3-((3S,6S)-6-Isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,...)copy SMILEScopy InChI
Affinity DataIC50: 225nMAssay Description:Inhibition of ABCG2 overexpressed in human MCF7/Topo cells by flow cytometric-based mitoxantrone efflux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PQ4PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50206310(5-Methoxy-9-oxo-9,10-dihydro-acridine-4-carboxylic...)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Inhibition of ABCG2 overexpressed in human MCF7/Topo cells by flow cytometric-based mitoxantrone efflux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PQ4PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50293022(CHEMBL446339 | N-(5-((4-(2-(6,7-Dimethoxy-1,2,3,4-...)copy SMILEScopy InChI
Affinity DataIC50: 317nMAssay Description:Inhibition of ABCG2 overexpressed in human MCF7/Topo cells by flow cytometric-based mitoxantrone efflux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PQ4PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50293012(CHEMBL457439 | Methyl 4-((4-(2-(6,7-dimethoxy-1,2,...)copy SMILEScopy InChI
Affinity DataIC50: 552nMAssay Description:Inhibition of ABCG2 overexpressed in human MCF7/Topo cells by flow cytometric-based mitoxantrone efflux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PQ4PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50293011(CHEMBL501349 | Methyl 4-((4-(2-(6,7-dimethoxy-1,2,...)copy SMILEScopy InChI
Affinity DataIC50: 632nMAssay Description:Inhibition of ABCG2 overexpressed in human MCF7/Topo cells by flow cytometric-based mitoxantrone efflux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PQ4PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50293021(CHEMBL506742 | N-(5-((4-(2-(6,7-Dimethoxy-1,2,3,4-...)copy SMILEScopy InChI
Affinity DataIC50: 858nMAssay Description:Inhibition of ABCG2 overexpressed in human MCF7/Topo cells by flow cytometric-based mitoxantrone efflux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PQ4PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50075373(1N-{4-[2-(6,7-dimethoxy-1,2,3,4-tetrahydro-2-isoqu...)copy SMILEScopy InChI
Affinity DataIC50: 916nMAssay Description:Inhibition of ABCG2 overexpressed in human MCF7/Topo cells by flow cytometric-based mitoxantrone efflux assayMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50293020(CHEMBL453516 | N-(3-((4-(2-(6,7-Dimethoxy-1,2,3,4-...)copy SMILEScopy InChI
Affinity DataIC50: 977nMAssay Description:Inhibition of ABCG2 overexpressed in human MCF7/Topo cells by flow cytometric-based mitoxantrone efflux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PQ4PubMed
TargetATP-binding cassette sub-family C member 2(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50013920(3-[(R)-{3-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]-p...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of ABCC2 overexpressed in MDCK cells at 100 uM by flow cytometric-based chloromethylfluorescein-diacetate accumulation assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PQ4PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50293019(CHEMBL456361 | Methyl 4-((4-(2-(6,7-dimethoxy-1,2,...)copy SMILEScopy InChI
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of ABCG2 overexpressed in human MCF7/Topo cells by flow cytometric-based mitoxantrone efflux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PQ4PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50293018(CHEMBL500094 | N-(5-((4-(2-(6,7-Dimethoxy-1,2,3,4-...)copy SMILEScopy InChI
Affinity DataIC50: 1.99E+3nMAssay Description:Inhibition of ABCG2 overexpressed in human MCF7/Topo cells by flow cytometric-based mitoxantrone efflux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PQ4PubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50293022(CHEMBL446339 | N-(5-((4-(2-(6,7-Dimethoxy-1,2,3,4-...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of ABCB1 overexpressed in human KBv1 cells by flow cytometric-based calcein-AM efflux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PQ4PubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50293016(CHEMBL453536 | Methyl 4-((4-(2-(6,7-dimethoxy-1,2,...)copy SMILEScopy InChI
Affinity DataIC50: 9.45E+3nMAssay Description:Inhibition of ABCB1 overexpressed in human KBv1 cells by flow cytometric-based calcein-AM efflux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PQ4PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM32628(FTC | Fumitremorgin C)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of ABCG2 overexpressed in human MCF7/Topo cells by flow cytometric-based mitoxantrone efflux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PQ4PubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50293019(CHEMBL456361 | Methyl 4-((4-(2-(6,7-dimethoxy-1,2,...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of ABCB1 overexpressed in human KBv1 cells by flow cytometric-based calcein-AM efflux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PQ4PubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50293020(CHEMBL453516 | N-(3-((4-(2-(6,7-Dimethoxy-1,2,3,4-...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of ABCB1 overexpressed in human KBv1 cells by flow cytometric-based calcein-AM efflux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PQ4PubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50293018(CHEMBL500094 | N-(5-((4-(2-(6,7-Dimethoxy-1,2,3,4-...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of ABCB1 overexpressed in human KBv1 cells by flow cytometric-based calcein-AM efflux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PQ4PubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50293021(CHEMBL506742 | N-(5-((4-(2-(6,7-Dimethoxy-1,2,3,4-...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of ABCB1 overexpressed in human KBv1 cells by flow cytometric-based calcein-AM efflux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PQ4PubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50293011(CHEMBL501349 | Methyl 4-((4-(2-(6,7-dimethoxy-1,2,...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of ABCB1 overexpressed in human KBv1 cells by flow cytometric-based calcein-AM efflux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PQ4PubMed
TargetATP-binding cassette sub-family C member 2(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50293015(CHEMBL502503 | Methyl 4-((4-(2-(6,7-Dimethoxy-1,2,...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of ABCC2 overexpressed in MDCK cells at 100 uM by flow cytometric-based chloromethylfluorescein-diacetate accumulation assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PQ4PubMed
TargetATP-binding cassette sub-family C member 2(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50293012(CHEMBL457439 | Methyl 4-((4-(2-(6,7-dimethoxy-1,2,...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of ABCC2 overexpressed in MDCK cells at 100 uM by flow cytometric-based chloromethylfluorescein-diacetate accumulation assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PQ4PubMed
TargetATP-binding cassette sub-family C member 2(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50293019(CHEMBL456361 | Methyl 4-((4-(2-(6,7-dimethoxy-1,2,...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of ABCC2 overexpressed in MDCK cells at 100 uM by flow cytometric-based chloromethylfluorescein-diacetate accumulation assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PQ4PubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50293015(CHEMBL502503 | Methyl 4-((4-(2-(6,7-Dimethoxy-1,2,...)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of ABCB1 overexpressed in human KBv1 cells by flow cytometric-based calcein-AM efflux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PQ4PubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50293014(CHEMBL506278 | Methyl 4-((4-(2-(6,7-dimethoxy-1,2,...)copy SMILEScopy InChI
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of ABCB1 overexpressed in human KBv1 cells by flow cytometric-based calcein-AM efflux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PQ4PubMed
TargetATP-binding cassette sub-family C member 2(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50305083(3-((3S,6S)-6-Isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of ABCC2 overexpressed in MDCK cells at 100 uM by flow cytometric-based chloromethylfluorescein-diacetate accumulation assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PQ4PubMed
TargetATP-binding cassette sub-family C member 2(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50293018(CHEMBL500094 | N-(5-((4-(2-(6,7-Dimethoxy-1,2,3,4-...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of ABCC2 overexpressed in MDCK cells at 100 uM by flow cytometric-based chloromethylfluorescein-diacetate accumulation assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PQ4PubMed
TargetATP-binding cassette sub-family C member 2(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50293011(CHEMBL501349 | Methyl 4-((4-(2-(6,7-dimethoxy-1,2,...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of ABCC2 overexpressed in MDCK cells at 100 uM by flow cytometric-based chloromethylfluorescein-diacetate accumulation assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PQ4PubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50293012(CHEMBL457439 | Methyl 4-((4-(2-(6,7-dimethoxy-1,2,...)copy SMILEScopy InChI
Affinity DataIC50: 5.70E+4nMAssay Description:Inhibition of ABCB1 overexpressed in human KBv1 cells by flow cytometric-based calcein-AM efflux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PQ4PubMed