Compile Data Set for Download or QSAR
Found 50 Enz. Inhib. hit(s) with all data for entry = 50038865
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50259277((R,S/S,R)-syn-1-((4-methoxyphenyl)(methyl)amino)-3...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JAR cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V1CPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50366567(ATOMOXETINE)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V1CPubMedDrugBank
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50124566((R)-2-((R)-(2-ethoxyphenoxy)(phenyl)methyl)morphol...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V1CPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM84745(CAS_136434-34-9 | DULOXETINE | LY-248686 | LY24868...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JAR cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V1CPubMedDrugBank
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM35229(3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-met...)copy SMILEScopy InChI
Affinity DataIC50: 3.40nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V1CPubMedDrugBank
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM84745(CAS_136434-34-9 | DULOXETINE | LY-248686 | LY24868...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V1CPubMedDrugBank
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM30130(CHEMBL1201082 | CHEMBL41 | Fluoxetin | Fluoxetine ...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JAR cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V1CPubMedDrugBank
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50259340((1S,2R)-1-(3-fluorophenyl)-1-(methyl(phenyl)amino)...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V1CPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50259276((R,S/S,R)-syn-1-((3-methoxyphenyl)(methyl)amino)-3...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JAR cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V1CPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50259273((R,S/S,R)-syn-1-((3-chlorophenyl)(methyl)amino)-3-...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V1CPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50005536(42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of [3H]WIN-35428 binding to human recombinant DAT expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V1CPubMedDrugBank
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50259274((R,S/S,R)-syn-1-((4-chlorophenyl)(methyl)amino)-3-...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JAR cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V1CPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50259274((R,S/S,R)-syn-1-((4-chlorophenyl)(methyl)amino)-3-...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V1CPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50259230((R,S/S,R)-syn-1-(methyl(p-tolyl)amino)-3-(methylam...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V1CPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50259227((R,S/S,R)-syn-1-(methyl(phenyl)amino)-3-(methylami...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V1CPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50259229((R,S/S,R)-syn-1-(methyl(m-tolyl)amino)-3-(methylam...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JAR cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V1CPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50259231((R,S/S,R)-syn-1-((4-fluorophenyl)(methyl)amino)-3-...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JAR cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V1CPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50259343((R,S/S,R)-syn-1-(4-methoxyphenyl)-1-(methyl(phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V1CPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50259273((R,S/S,R)-syn-1-((3-chlorophenyl)(methyl)amino)-3-...)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JAR cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V1CPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50366567(ATOMOXETINE)copy SMILEScopy InChI
Affinity DataIC50: 48nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JAR cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V1CPubMedDrugBank
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50259343((R,S/S,R)-syn-1-(4-methoxyphenyl)-1-(methyl(phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 55nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JAR cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V1CPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50259229((R,S/S,R)-syn-1-(methyl(m-tolyl)amino)-3-(methylam...)copy SMILEScopy InChI
Affinity DataIC50: 61nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V1CPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50259231((R,S/S,R)-syn-1-((4-fluorophenyl)(methyl)amino)-3-...)copy SMILEScopy InChI
Affinity DataIC50: 62nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V1CPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50259344((R,S/S,R)-syn-3-amino-1-(methyl(phenyl)amino)-1-ph...)copy SMILEScopy InChI
Affinity DataIC50: 68nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V1CPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50259341((R,S/S,R)-syn-1-(3-chlorophenyl)-1-(methyl(phenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 73nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V1CPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50259230((R,S/S,R)-syn-1-(methyl(p-tolyl)amino)-3-(methylam...)copy SMILEScopy InChI
Affinity DataIC50: 73nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JAR cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V1CPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50259227((R,S/S,R)-syn-1-(methyl(phenyl)amino)-3-(methylami...)copy SMILEScopy InChI
Affinity DataIC50: 76nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JAR cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V1CPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50259277((R,S/S,R)-syn-1-((4-methoxyphenyl)(methyl)amino)-3...)copy SMILEScopy InChI
Affinity DataIC50: 99nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V1CPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50259342((R,S/S,R)-syn-1-(4-chlorophenyl)-1-(methyl(phenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V1CPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50259340((1S,2R)-1-(3-fluorophenyl)-1-(methyl(phenyl)amino)...)copy SMILEScopy InChI
Affinity DataIC50: 112nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JAR cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V1CPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50259278((R,S/S,R)-syn-1-(methyl(naphthalen-1-yl)amino)-3-(...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V1CPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50259394((R,S/S,R)-syn-3-amino-1-(4-methoxyphenyl)-1-(methy...)copy SMILEScopy InChI
Affinity DataIC50: 156nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V1CPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50259342((R,S/S,R)-syn-1-(4-chlorophenyl)-1-(methyl(phenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 167nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JAR cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V1CPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50259394((R,S/S,R)-syn-3-amino-1-(4-methoxyphenyl)-1-(methy...)copy SMILEScopy InChI
Affinity DataIC50: 183nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JAR cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V1CPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50259344((R,S/S,R)-syn-3-amino-1-(methyl(phenyl)amino)-1-ph...)copy SMILEScopy InChI
Affinity DataIC50: 196nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JAR cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V1CPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50259228((1S,2R)-1-(methyl(o-tolyl)amino)-3-(methylamino)-1...)copy SMILEScopy InChI
Affinity DataIC50: 217nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V1CPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50259341((R,S/S,R)-syn-1-(3-chlorophenyl)-1-(methyl(phenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 237nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JAR cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V1CPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50259232((R,S/S,R)-syn-1-((2-chlorophenyl)(methyl)amino)-3-...)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V1CPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50124566((R)-2-((R)-(2-ethoxyphenoxy)(phenyl)methyl)morphol...)copy SMILEScopy InChI
Affinity DataIC50: 242nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JAR cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V1CPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50259232((R,S/S,R)-syn-1-((2-chlorophenyl)(methyl)amino)-3-...)copy SMILEScopy InChI
Affinity DataIC50: 286nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JAR cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V1CPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50259275((R,S/S,R)-syn-1-((2-methoxyphenyl)(methyl)amino)-3...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V1CPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50259276((R,S/S,R)-syn-1-((3-methoxyphenyl)(methyl)amino)-3...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V1CPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50259395((R,R/S,S)-anti-1-(methyl(phenyl)amino)-3-(methylam...)copy SMILEScopy InChI
Affinity DataIC50: 416nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JAR cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V1CPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50259393((R,S/S,R)-syn-3-amino-1-(3-fluorophenyl)-1-(methyl...)copy SMILEScopy InChI
Affinity DataIC50: 439nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JAR cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V1CPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50259393((R,S/S,R)-syn-3-amino-1-(3-fluorophenyl)-1-(methyl...)copy SMILEScopy InChI
Affinity DataIC50: 550nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V1CPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM30130(CHEMBL1201082 | CHEMBL41 | Fluoxetin | Fluoxetine ...)copy SMILEScopy InChI
Affinity DataIC50: 563nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V1CPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50259278((R,S/S,R)-syn-1-(methyl(naphthalen-1-yl)amino)-3-(...)copy SMILEScopy InChI
Affinity DataIC50: 836nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JAR cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V1CPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50259395((R,R/S,S)-anti-1-(methyl(phenyl)amino)-3-(methylam...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V1CPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50259275((R,S/S,R)-syn-1-((2-methoxyphenyl)(methyl)amino)-3...)copy SMILEScopy InChI
Affinity DataIC50: 2.11E+3nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JAR cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V1CPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50259228((1S,2R)-1-(methyl(o-tolyl)amino)-3-(methylamino)-1...)copy SMILEScopy InChI
Affinity DataIC50: 2.61E+3nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JAR cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V1CPubMed