Compile Data Set for Download or QSAR
Found 27 Enz. Inhib. hit(s) with all data for entry = 50039178
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM22372(4-[(2R,3S)-4-(3,4-dihydroxyphenyl)-2,3-dimethylbut...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of human N-terminal His6-tagged 5-lipoxygenase arachidonic acid by UV-vis spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB82TDPubMedDrugBank
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50240936(2-[(2E,6E)-3,7-Dimethyl-9-(2,6,6-trimethyl-cyclohe...)copy SMILEScopy InChI
Affinity DataIC50: 450nMAssay Description:Inhibition of human N-terminal His6-tagged 5-lipoxygenase arachidonic acid by UV-vis spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB82TDPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50320449((-)-ZILEUTON | CHEMBL1164975)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of human N-terminal His6-tagged 5-lipoxygenase arachidonic acid by UV-vis spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB82TDPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50240865((4aS,6aS,12aR,12bS)-10-Hydroxy-4,4,6a,12b-tetramet...)copy SMILEScopy InChI
Affinity DataIC50: 680nMAssay Description:Inhibition of human N-terminal His6-tagged 5-lipoxygenase arachidonic acid by UV-vis spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB82TDPubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM22372(4-[(2R,3S)-4-(3,4-dihydroxyphenyl)-2,3-dimethylbut...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human reticulocyte N-terminal His6-tagged 15-lipoxygenase by UV-vis spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB82TDPubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50320447(CHEMBL1164369 | isojaspic acid)copy SMILEScopy InChI
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of human 12-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB82TDPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50320451(CHEMBL1163875 | puupehedione)copy SMILEScopy InChI
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of human N-terminal His6-tagged 5-lipoxygenase arachidonic acid by UV-vis spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB82TDPubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50320448(CHEMBL1163939 | jaspic acid)copy SMILEScopy InChI
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of human reticulocyte N-terminal His6-tagged 15-lipoxygenase by UV-vis spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB82TDPubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50320447(CHEMBL1164369 | isojaspic acid)copy SMILEScopy InChI
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of human 15-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB82TDPubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM22372(4-[(2R,3S)-4-(3,4-dihydroxyphenyl)-2,3-dimethylbut...)copy SMILEScopy InChI
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of human platelet N-terminal His6-tagged 12-lipoxygenase by UV-vis spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB82TDPubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50240865((4aS,6aS,12aR,12bS)-10-Hydroxy-4,4,6a,12b-tetramet...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human reticulocyte N-terminal His6-tagged 15-lipoxygenase by UV-vis spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB82TDPubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50320451(CHEMBL1163875 | puupehedione)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of human reticulocyte N-terminal His6-tagged 15-lipoxygenase by UV-vis spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB82TDPubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50320448(CHEMBL1163939 | jaspic acid)copy SMILEScopy InChI
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of human platelet N-terminal His6-tagged 12-lipoxygenase by UV-vis spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB82TDPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50320448(CHEMBL1163939 | jaspic acid)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of human N-terminal His6-tagged 5-lipoxygenase arachidonic acid by UV-vis spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB82TDPubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50320447(CHEMBL1164369 | isojaspic acid)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of human reticulocyte N-terminal His6-tagged 15-lipoxygenase by UV-vis spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB82TDPubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50320451(CHEMBL1163875 | puupehedione)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of human platelet N-terminal His6-tagged 12-lipoxygenase by UV-vis spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB82TDPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50320447(CHEMBL1164369 | isojaspic acid)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of human N-terminal His6-tagged 5-lipoxygenase arachidonic acid by UV-vis spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB82TDPubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50240936(2-[(2E,6E)-3,7-Dimethyl-9-(2,6,6-trimethyl-cyclohe...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of human reticulocyte N-terminal His6-tagged 15-lipoxygenase by UV-vis spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB82TDPubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50240865((4aS,6aS,12aR,12bS)-10-Hydroxy-4,4,6a,12b-tetramet...)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of human platelet N-terminal His6-tagged 12-lipoxygenase by UV-vis spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB82TDPubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50320447(CHEMBL1164369 | isojaspic acid)copy SMILEScopy InChI
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of human platelet N-terminal His6-tagged 12-lipoxygenase by UV-vis spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB82TDPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50320452(20-hydroxyhaterumadienone | CHEMBL1165577)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human N-terminal His6-tagged 5-lipoxygenase arachidonic acid by UV-vis spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB82TDPubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50240936(2-[(2E,6E)-3,7-Dimethyl-9-(2,6,6-trimethyl-cyclohe...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human platelet N-terminal His6-tagged 12-lipoxygenase by UV-vis spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB82TDPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50320453(15-Oxo-puupehenoic Acid | CHEMBL1165243)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of human N-terminal His6-tagged 5-lipoxygenase arachidonic acid by UV-vis spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB82TDPubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50320453(15-Oxo-puupehenoic Acid | CHEMBL1165243)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of human reticulocyte N-terminal His6-tagged 15-lipoxygenase by UV-vis spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB82TDPubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50320453(15-Oxo-puupehenoic Acid | CHEMBL1165243)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of human platelet N-terminal His6-tagged 12-lipoxygenase by UV-vis spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB82TDPubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50320452(20-hydroxyhaterumadienone | CHEMBL1165577)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of human reticulocyte N-terminal His6-tagged 15-lipoxygenase by UV-vis spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB82TDPubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50320452(20-hydroxyhaterumadienone | CHEMBL1165577)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of human platelet N-terminal His6-tagged 12-lipoxygenase by UV-vis spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB82TDPubMed