Compile Data Set for Download or QSAR
Found 108 Enz. Inhib. hit(s) with all data for entry = 50039261
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324200(4-[(5R)-1-(3-Chloro-4-cyanophenyl)-5-cyclopentyl-4...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324215((+/-)-(3SR,3aRS)-2-(4-Cyano-3-methylphenyl)-3-cycl...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324201(4-[(5R)-1-(3-Chloro-4-cyanophenyl)-5-cyclopentyl-4...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324216((+/-)-(3SR,3aRS)-2-(4-Cyano-3-methoxyphenyl)-3-cyc...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50228080(2',15'-dimethyl-5,5'-dioxo-(9'R)-spiro[tetrahydrof...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324202(4-[(5R)-1-(3-Chloro-4-cyanophenyl)-5-cyclopentyl-4...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324199(4-[(5R)-1-(3-Chloro-4-cyanophenyl)-5-cyclopentyl-4...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324212((+/-)-(3RS,3aRS)-2-(3-Chloro-4-cyanophenyl)-3-cycl...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324196(4-[(5R)-1-(3-Chloro-4-cyanophenyl)-5-cyclopentyl-4...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324210((+/-)-(3SR,3aRS)-2-(3-Chloro-4-cyanophenyl)-3-cycl...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324211((+/-)-(3RS,3aSR)-2-(3-Chloro-4-cyanophenyl)-3-cycl...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324210((+/-)-(3SR,3aRS)-2-(3-Chloro-4-cyanophenyl)-3-cycl...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324224((3S,3aR)-2-(3-Chloro-4-cyanophenyl)-3-cyclopentyl-...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324198(2-Chloro-4-[(5R)-1-(3-chloro-4-cyanophenyl)-5-cycl...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324226((3S,3aR)-2-(4-Cyano-3-methylphenyl)-3-cyclopentyl-...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324163(4-[(5R)-5-(4-Fluorophenyl)-3-(2-oxo-2,3-dihydro-1,...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Displacement of [3H]dofetilide from human ERG at 10 uMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324227(4-[(5R)-1-(3-Chloro-4-cyanophenyl)-5-(4-fluorophen...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324165(4-[(5R)-3-(2,4-Dimethyl-1,3-thiazol-5-yl)-5-(4-flu...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324223((+/-)-(3RS,3aSR)-2-(4-Cyano-3-methylphenyl)-3-cycl...)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324209((3R,3aR)-2-(3-Chloro-4-cyanophenyl)-3-(4-fluorophe...)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324163(4-[(5R)-5-(4-Fluorophenyl)-3-(2-oxo-2,3-dihydro-1,...)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324197(4-[(5R)-1-(3-Chloro-4-cyanophenyl)-5-cyclopentyl-4...)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324195((+/-)-4-[1-(3-Chloro-4-cyanophenyl)-5-cyclopentyl-...)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324180((+/-)-4-[1-(4-Cyano-3-methylphenyl)-5-(4-fluorophe...)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324178((+/-)-4-[1-(3-Chloro-4-cyanophenyl)-5-(4-fluorophe...)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324162((+/-)-4-[5-(4-Fluorophenyl)-3-(2-oxo-2,3-dihydro-1...)copy SMILEScopy InChI
Affinity DataIC50: 58nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324221((+/-)-(3RS,3aSR)-2-(3-Chloro-4-cyanophenyl)-3-cycl...)copy SMILEScopy InChI
Affinity DataIC50: 65nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324205(4-[(4S,5S)-1-(3-Chloro-4-cyanophenyl)-5-cyclopenty...)copy SMILEScopy InChI
Affinity DataIC50: 69nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324203(4-[(5R)-1-(3-Chloro-4-cyanophenyl)-5-cyclopentyl-4...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324166((+/-)-4-[1-(4-Cyanophenyl)-5-(4-fluorophenyl)-4,5-...)copy SMILEScopy InChI
Affinity DataIC50: 83nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324160((+/-)-(3SR,3aRS)-2-(4-Cyanophenyl)-3-cyclopentyl-3...)copy SMILEScopy InChI
Affinity DataIC50: 89nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324170(4-[(5R)-1-(4-Cyanophenyl)-5-(4-fluorophenyl)-4,5-d...)copy SMILEScopy InChI
Affinity DataIC50: 101nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50318300(CHEMBL1095097 | EPLERENONE | SC-66110)copy SMILEScopy InChI
Affinity DataIC50: 122nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324181((+/-)-4-{1-[4-Cyano-3-(trifluoromethyl)phenyl]-5-(...)copy SMILEScopy InChI
Affinity DataIC50: 127nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324214((+/-)-(3SR,3aRS)-2-(3-Chloro-4-cyanophenyl)-3-(tet...)copy SMILEScopy InChI
Affinity DataIC50: 127nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324204(CHEMBL1215262 | {4-[(5R)-1-(3-Chloro-4-cyanophenyl...)copy SMILEScopy InChI
Affinity DataIC50: 135nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324222((+/-)-(3RS,3aRS)-2-(3-Chloro-4-cyanophenyl)-3-cycl...)copy SMILEScopy InChI
Affinity DataIC50: 146nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324217((+/-)-(3RS,3aSR)-2-(4-Cyano-3-(methoxymethyl)pheny...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324192((+/-)-4-[1-(4-Cyanophenyl)-5-cyclopentyl-4,5-dihyd...)copy SMILEScopy InChI
Affinity DataIC50: 151nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324166((+/-)-4-[1-(4-Cyanophenyl)-5-(4-fluorophenyl)-4,5-...)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Displacement of [3H]dofetilide from human ERG at 10 uMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324173((+/-)-4-{1-[4-(Ethoxycarbonyl)phenyl]-5-(4-fluorop...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324208((+/-)-(3RS,3aRS)-2-(3-Chloro-4-cyanophenyl)-3-(4-f...)copy SMILEScopy InChI
Affinity DataIC50: 223nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324208((+/-)-(3RS,3aRS)-2-(3-Chloro-4-cyanophenyl)-3-(4-f...)copy SMILEScopy InChI
Affinity DataIC50: 223nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324176((+/-)-4-[1-(4-Cyano-3-fluorophenyl)-5-(4-fluorophe...)copy SMILEScopy InChI
Affinity DataIC50: 243nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324169((+/-)-4-[1-(4-Cyanophenyl)-5-(4-fluorophenyl)-4,5-...)copy SMILEScopy InChI
Affinity DataIC50: 246nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324179((+/-)-4-[1-(2-Chloro-4-cyanophenyl)-5-(4-fluorophe...)copy SMILEScopy InChI
Affinity DataIC50: 284nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324193((+/-)-4-[1-(3-Chloro-4-cyanophenyl)-5-isopropyl-4,...)copy SMILEScopy InChI
Affinity DataIC50: 383nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324186((+/-)-4-[1-(4-Cyanophenyl)-5-(2-furyl)-4,5-dihydro...)copy SMILEScopy InChI
Affinity DataIC50: 410nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetProgesterone receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324210((+/-)-(3SR,3aRS)-2-(3-Chloro-4-cyanophenyl)-3-cycl...)copy SMILEScopy InChI
Affinity DataIC50: 416nMAssay Description:Antagonist activity at progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324189((+/-)-4-[1-(4-Cyanophenyl)-5-(3-fluorophenyl)-4,5-...)copy SMILEScopy InChI
Affinity DataIC50: 441nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
Displayed 1 to 50 (of 108 total ) | Next | Last >>
Jump to: