Compile Data Set for Download or QSAR
Found 20 Enz. Inhib. hit(s) with all data for entry = 50039319
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50317662(3-[3-(3-Chloro-4-cyanophenyl)-5,5-dimethyl-4-oxo-2...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Antagonist activity at AR in human bicalutamide-resistant LNCAP cells assessed as inhibition of cell proliferation after 6 daysMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1S1PPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50331872(5-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethy...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Antagonist activity at AR in human bicalutamide-resistant LNCAP cells assessed as inhibition of cell proliferation after 6 daysMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1S1PPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50331871(5-[3-(3-Chloro-4-cyanophenyl)-5,5-dimethyl-4-oxo-2...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Antagonist activity at AR in human bicalutamide-resistant LNCAP cells assessed as inhibition of cell proliferation after 6 daysMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1S1PPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50331870(4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethy...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Antagonist activity at AR in human bicalutamide-resistant LNCAP cells assessed as inhibition of cell proliferation after 6 daysMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1S1PPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50331866(3-[3-(3-Chloro-4-cyanophenyl)-5,5-dimethyl-4-oxo-2...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Antagonist activity at AR in human bicalutamide-resistant LNCAP cells assessed as inhibition of cell proliferation after 6 daysMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1S1PPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50331869(6-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethy...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Antagonist activity at AR in human bicalutamide-resistant LNCAP cells assessed as inhibition of cell proliferation after 6 daysMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1S1PPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50331868(6-[3-(3-Chloro-4-cyanophenyl)-5,5-dimethyl-4-oxo-2...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Antagonist activity at AR in human bicalutamide-resistant LNCAP cells assessed as inhibition of cell proliferation after 6 daysMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1S1PPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50331867(3-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethy...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Antagonist activity at AR in human bicalutamide-resistant LNCAP cells assessed as inhibition of cell proliferation after 6 daysMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1S1PPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50331865(4-(3-Phenyl-4,4-dimethyl-5-oxo-2-thioxoimidazolidi...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Antagonist activity at AR in human bicalutamide-resistant LNCAP cells assessed as inhibition of cell proliferation after 6 daysMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1S1PPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50317662(3-[3-(3-Chloro-4-cyanophenyl)-5,5-dimethyl-4-oxo-2...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Antagonist activity at human AR expressed in human HeLa cells co-transfected with MMTV-Luc-Hyg after 48 hrs by transient-luciferase reporter gene ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1S1PPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM18525(Bicalutamide | CHEMBL409 | N-[4-cyano-3-(trifluoro...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Antagonist activity at human AR expressed in human HeLa cells co-transfected with MMTV-Luc-Hyg after 48 hrs by transient-luciferase reporter gene ass...More data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50331865(4-(3-Phenyl-4,4-dimethyl-5-oxo-2-thioxoimidazolidi...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Antagonist activity at human AR expressed in human HeLa cells co-transfected with MMTV-Luc-Hyg after 48 hrs by transient-luciferase reporter gene ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1S1PPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50331867(3-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethy...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Antagonist activity at human AR expressed in human HeLa cells co-transfected with MMTV-Luc-Hyg after 48 hrs by transient-luciferase reporter gene ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1S1PPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50331866(3-[3-(3-Chloro-4-cyanophenyl)-5,5-dimethyl-4-oxo-2...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Antagonist activity at human AR expressed in human HeLa cells co-transfected with MMTV-Luc-Hyg after 48 hrs by transient-luciferase reporter gene ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1S1PPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50331868(6-[3-(3-Chloro-4-cyanophenyl)-5,5-dimethyl-4-oxo-2...)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:Antagonist activity at human AR expressed in human HeLa cells co-transfected with MMTV-Luc-Hyg after 48 hrs by transient-luciferase reporter gene ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1S1PPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM18525(Bicalutamide | CHEMBL409 | N-[4-cyano-3-(trifluoro...)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:Antagonist activity at AR in human bicalutamide-resistant LNCAP cells assessed as inhibition of cell proliferation after 6 daysMore data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50331869(6-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethy...)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:Antagonist activity at human AR expressed in human HeLa cells co-transfected with MMTV-Luc-Hyg after 48 hrs by transient-luciferase reporter gene ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1S1PPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50331872(5-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethy...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human AR expressed in human HeLa cells co-transfected with MMTV-Luc-Hyg after 48 hrs by transient-luciferase reporter gene ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1S1PPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50331870(4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethy...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human AR expressed in human HeLa cells co-transfected with MMTV-Luc-Hyg after 48 hrs by transient-luciferase reporter gene ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1S1PPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50331871(5-[3-(3-Chloro-4-cyanophenyl)-5,5-dimethyl-4-oxo-2...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Antagonist activity at human AR expressed in human HeLa cells co-transfected with MMTV-Luc-Hyg after 48 hrs by transient-luciferase reporter gene ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1S1PPubMed