Compile Data Set for Download or QSAR
Found 102 Enz. Inhib. hit(s) with all data for entry = 50039845
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50385037(CHEMBL2035600)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human 11beta-HSD1 using [3H]cortisone as substrate assessed as production of [3H]-cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5G07PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50385035(CHEMBL2035431)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human 11beta-HSD1 using [3H]cortisone as substrate assessed as production of [3H]-cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5G07PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50385037(CHEMBL2035600)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human 11beta-HSD1 expressed in human HEK293 cells using [3H]cortisone as substrate assessed as production of [3H]-cortisol by scintilla...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5G07PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50385046(CHEMBL2035410)copy SMILEScopy InChI
Affinity DataIC50: 3.10nMAssay Description:Inhibition of human 11beta-HSD1 using [3H]cortisone as substrate assessed as production of [3H]-cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5G07PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50385037(CHEMBL2035600)copy SMILEScopy InChI
Affinity DataIC50: 3.10nMAssay Description:Inhibition of human 11beta-HSD1 using [3H]cortisone as substrate assessed as production of [3H]-cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5G07PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50385051(CHEMBL2035418)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human 11beta-HSD1 using [3H]cortisone as substrate assessed as production of [3H]-cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5G07PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50385035(CHEMBL2035431)copy SMILEScopy InChI
Affinity DataIC50: 3.40nMAssay Description:Inhibition of human 11beta-HSD1 using [3H]cortisone as substrate assessed as production of [3H]-cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5G07PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50385024(CHEMBL2035419)copy SMILEScopy InChI
Affinity DataIC50: 4.5nMAssay Description:Inhibition of human 11beta-HSD1 using [3H]cortisone as substrate assessed as production of [3H]-cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5G07PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50385043(CHEMBL2035407)copy SMILEScopy InChI
Affinity DataIC50: 5.30nMAssay Description:Inhibition of human 11beta-HSD1 using [3H]cortisone as substrate assessed as production of [3H]-cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5G07PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50385035(CHEMBL2035431)copy SMILEScopy InChI
Affinity DataIC50: 5.80nMAssay Description:Inhibition of human 11beta-HSD1 expressed in human HEK293 cells using [3H]cortisone as substrate assessed as production of [3H]-cortisol by scintilla...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5G07PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50385039(CHEMBL2035403)copy SMILEScopy InChI
Affinity DataIC50: 6.60nMAssay Description:Inhibition of human 11beta-HSD1 expressed in human HEK293 cells using [3H]cortisone as substrate assessed as production of [3H]-cortisol by scintilla...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5G07PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50385040(CHEMBL2035404)copy SMILEScopy InChI
Affinity DataIC50: 7.40nMAssay Description:Inhibition of human 11beta-HSD1 using [3H]cortisone as substrate assessed as production of [3H]-cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5G07PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50385035(CHEMBL2035431)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of human 11beta-HSD1 expressed in human HEK293 cells using [3H]cortisone as substrate assessed as production of [3H]-cortisol by scintilla...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5G07PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50385037(CHEMBL2035600)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of human 11beta-HSD1 expressed in human HEK293 cells using [3H]cortisone as substrate assessed as production of [3H]-cortisol by scintilla...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5G07PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50385047(CHEMBL2035411)copy SMILEScopy InChI
Affinity DataIC50: 9.70nMAssay Description:Inhibition of human 11beta-HSD1 using [3H]cortisone as substrate assessed as production of [3H]-cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5G07PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50385040(CHEMBL2035404)copy SMILEScopy InChI
Affinity DataIC50: 9.90nMAssay Description:Inhibition of human 11beta-HSD1 expressed in human HEK293 cells using [3H]cortisone as substrate assessed as production of [3H]-cortisol by scintilla...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5G07PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50385048(CHEMBL2035415)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human 11beta-HSD1 using [3H]cortisone as substrate assessed as production of [3H]-cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5G07PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50385057(CHEMBL2035414)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human 11beta-HSD1 using [3H]cortisone as substrate assessed as production of [3H]-cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5G07PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50385028(CHEMBL2035423)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human 11beta-HSD1 using [3H]cortisone as substrate assessed as production of [3H]-cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5G07PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50385039(CHEMBL2035403)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of human 11beta-HSD1 using [3H]cortisone as substrate assessed as production of [3H]-cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5G07PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50385049(CHEMBL2035416)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of human 11beta-HSD1 using [3H]cortisone as substrate assessed as production of [3H]-cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5G07PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50385022(CHEMBL2035401)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of human 11beta-HSD1 using [3H]cortisone as substrate assessed as production of [3H]-cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5G07PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50385048(CHEMBL2035415)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of human 11beta-HSD1 expressed in human HEK293 cells using [3H]cortisone as substrate assessed as production of [3H]-cortisol by scintilla...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5G07PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50385051(CHEMBL2035418)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of human 11beta-HSD1 expressed in human HEK293 cells using [3H]cortisone as substrate assessed as production of [3H]-cortisol by scintilla...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5G07PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50385027(CHEMBL2035422)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of human 11beta-HSD1 expressed in human HEK293 cells using [3H]cortisone as substrate assessed as production of [3H]-cortisol by scintilla...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5G07PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50385056(CHEMBL2035412)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of human 11beta-HSD1 using [3H]cortisone as substrate assessed as production of [3H]-cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5G07PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50385024(CHEMBL2035419)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of human 11beta-HSD1 expressed in human HEK293 cells using [3H]cortisone as substrate assessed as production of [3H]-cortisol by scintilla...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5G07PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50385032(CHEMBL2035428)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of human 11beta-HSD1 using [3H]cortisone as substrate assessed as production of [3H]-cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5G07PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50385023(CHEMBL2035424)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human 11beta-HSD1 using [3H]cortisone as substrate assessed as production of [3H]-cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5G07PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50385037(CHEMBL2035600)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of human 11beta-HSD1 expressed in human HEK293 cells using [3H]cortisone as substrate assessed as production of [3H]-cortisol by scintilla...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5G07PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50385025(CHEMBL2035420)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of human 11beta-HSD1 using [3H]cortisone as substrate assessed as production of [3H]-cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5G07PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50385052(CHEMBL2035399)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of human 11beta-HSD1 using [3H]cortisone as substrate assessed as production of [3H]-cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5G07PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50385035(CHEMBL2035431)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of human 11beta-HSD1 expressed in human HEK293 cells using [3H]cortisone as substrate assessed as production of [3H]-cortisol by scintilla...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5G07PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50385055(CHEMBL2035402)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of human 11beta-HSD1 using [3H]cortisone as substrate assessed as production of [3H]-cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5G07PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50385032(CHEMBL2035428)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of human 11beta-HSD1 expressed in human HEK293 cells using [3H]cortisone as substrate assessed as production of [3H]-cortisol by scintilla...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5G07PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50385041(CHEMBL2035405)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of human 11beta-HSD1 expressed in human HEK293 cells using [3H]cortisone as substrate assessed as production of [3H]-cortisol by scintilla...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5G07PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50385041(CHEMBL2035405)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of human 11beta-HSD1 using [3H]cortisone as substrate assessed as production of [3H]-cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5G07PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50385042(CHEMBL2035406)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Inhibition of human 11beta-HSD1 using [3H]cortisone as substrate assessed as production of [3H]-cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5G07PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50385027(CHEMBL2035422)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of human 11beta-HSD1 using [3H]cortisone as substrate assessed as production of [3H]-cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5G07PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50385044(CHEMBL2035408)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of human 11beta-HSD1 using [3H]cortisone as substrate assessed as production of [3H]-cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5G07PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50385028(CHEMBL2035423)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Inhibition of human 11beta-HSD1 expressed in human HEK293 cells using [3H]cortisone as substrate assessed as production of [3H]-cortisol by scintilla...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5G07PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50385026(CHEMBL2035421)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Inhibition of human 11beta-HSD1 using [3H]cortisone as substrate assessed as production of [3H]-cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5G07PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50385023(CHEMBL2035424)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:Inhibition of human 11beta-HSD1 expressed in human HEK293 cells using [3H]cortisone as substrate assessed as production of [3H]-cortisol by scintilla...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5G07PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50385030(CHEMBL2035426)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:Inhibition of human 11beta-HSD1 using [3H]cortisone as substrate assessed as production of [3H]-cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5G07PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50385025(CHEMBL2035420)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Inhibition of human 11beta-HSD1 expressed in human HEK293 cells using [3H]cortisone as substrate assessed as production of [3H]-cortisol by scintilla...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5G07PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50385040(CHEMBL2035404)copy SMILEScopy InChI
Affinity DataIC50: 48nMAssay Description:Inhibition of human 11beta-HSD1 expressed in human HEK293 cells using [3H]cortisone as substrate assessed as production of [3H]-cortisol by scintilla...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5G07PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50385035(CHEMBL2035431)copy SMILEScopy InChI
Affinity DataIC50: 49nMAssay Description:Inhibition of human 11beta-HSD1 expressed in human HEK293 cells using [3H]cortisone as substrate assessed as production of [3H]-cortisol by scintilla...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5G07PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50385037(CHEMBL2035600)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:Inhibition of human 11beta-HSD1 expressed in human HEK293 cells using [3H]cortisone as substrate assessed as production of [3H]-cortisol by scintilla...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5G07PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50385029(CHEMBL2035425)copy SMILEScopy InChI
Affinity DataIC50: 61nMAssay Description:Inhibition of human 11beta-HSD1 using [3H]cortisone as substrate assessed as production of [3H]-cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5G07PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50385049(CHEMBL2035416)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Inhibition of human 11beta-HSD1 expressed in human HEK293 cells using [3H]cortisone as substrate assessed as production of [3H]-cortisol by scintilla...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5G07PubMed
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