Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with all data for entry = 50039970
TargetUbiquitin-like modifier-activating enzyme 1(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50387035(CHEMBL2046768)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of FLAG-tagged ubiquitin-activating enzyme E1 assessed as inhibition of GST-ubiquitin/FLAG-E1 intermediate formation by Western blot analy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2R2MPubMed
TargetUbiquitin-like modifier-activating enzyme 1(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50322422(CHEMBL1173445 | Largazole)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of recombinant fluorescein-tagged E1 assessed as inhibition of ubiquitin-E1 adduct formation incubated for 15 mins prior to ATP addition m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2R2MPubMed
TargetUbiquitin-like modifier-activating enzyme 1(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50387034(CHEMBL2046769)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of FLAG-tagged ubiquitin-activating enzyme E1 assessed as inhibition of GST-ubiquitin/FLAG-E1 intermediate formation by Western blot analy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2R2MPubMed
TargetUbiquitin-like modifier-activating enzyme 1(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50387036(CHEMBL2046774)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of ubiquitin-activating enzyme E1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2R2MPubMed