Compile Data Set for Download or QSAR
Found 281 Enz. Inhib. hit(s) with all data for entry = 50040092
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi Research& Development

Curated by ChEMBL
LigandPNGBDBM50365890(CHEMBL1957875)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human PI3Kbeta-mediated Akt phosphorylation at T308 residue expressed in PTEN-deficient human PC3 cells after 2 hrs by Western blot ana...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78G88PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi Research& Development

Curated by ChEMBL
LigandPNGBDBM50389047(CHEMBL2064328)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human PI3Kbeta-mediated Akt phosphorylation at T308 residue expressed in PTEN-deficient human PC3 cells after 2 hrs by Western blot ana...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78G88PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi Research& Development

Curated by ChEMBL
LigandPNGBDBM50389047(CHEMBL2064328)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human PI3Kbeta-mediated Akt phosphorylation at Ser473 residue expressed in PTEN-deficient human PC3 cells by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78G88PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi Research& Development

Curated by ChEMBL
LigandPNGBDBM50389048(CHEMBL2064417)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of human PI3Kbeta-mediated Akt phosphorylation at Ser473 residue expressed in PTEN-deficient human PC3 cells by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78G88PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi Research& Development

Curated by ChEMBL
LigandPNGBDBM50389069(CHEMBL2064344)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of human PI3Kbeta-mediated Akt phosphorylation at Ser473 residue expressed in PTEN-deficient human PC3 cells by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78G88PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi Research& Development

Curated by ChEMBL
LigandPNGBDBM50389048(CHEMBL2064417)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of N-terminus poly-His tagged human PI3Kbeta expressed in baculovirus infected insect S21 cells coexpressing p85alpha using PI(4,5)P2 as s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78G88PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi Research& Development

Curated by ChEMBL
LigandPNGBDBM50389072(CHEMBL2064341)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of human PI3Kbeta-mediated Akt phosphorylation at Ser473 residue expressed in PTEN-deficient human PC3 cells by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78G88PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi Research& Development

Curated by ChEMBL
LigandPNGBDBM50365890(CHEMBL1957875)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human PI3Kbeta-mediated Akt phosphorylation at Ser473 residue expressed in PTEN-deficient human PC3 cells by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78G88PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi Research& Development

Curated by ChEMBL
LigandPNGBDBM50389067(CHEMBL2064346)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of N-terminus poly-His tagged human PI3Kbeta expressed in baculovirus infected insect S21 cells coexpressing p85alpha using PI(4,5)P2 as s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78G88PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi Research& Development

Curated by ChEMBL
LigandPNGBDBM50365890(CHEMBL1957875)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of human PI3Kbeta-mediated Akt phosphorylation at Ser473 residue expressed in mouse MEF-3T3 cells after 0.5 to 2 hrs by Western blot analy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78G88PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi Research& Development

Curated by ChEMBL
LigandPNGBDBM50389054(CHEMBL2064411)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human PI3Kbeta-mediated Akt phosphorylation at Ser473 residue expressed in PTEN-deficient human PC3 cells by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78G88PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi Research& Development

Curated by ChEMBL
LigandPNGBDBM50389041(CHEMBL2064333)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of human PI3Kbeta-mediated Akt phosphorylation at Ser473 residue expressed in PTEN-deficient human PC3 cells by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78G88PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi Research& Development

Curated by ChEMBL
LigandPNGBDBM50389065(CHEMBL2064348)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of human PI3Kbeta-mediated Akt phosphorylation at Ser473 residue expressed in PTEN-deficient human PC3 cells by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78G88PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi Research& Development

Curated by ChEMBL
LigandPNGBDBM50389054(CHEMBL2064411)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of N-terminus poly-His tagged human PI3Kbeta expressed in baculovirus infected insect S21 cells coexpressing p85alpha using PI(4,5)P2 as s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78G88PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Sanofi Research& Development

Curated by ChEMBL
LigandPNGBDBM50389070(CHEMBL2064343)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of poly-His tagged human PI3Kdelta expressed in baculovirus infected insect sf9 cells coexpressing p85alpha using PI(4,5)P2 as substrate p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78G88PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi Research& Development

Curated by ChEMBL
LigandPNGBDBM50389052(CHEMBL2064413)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of human PI3Kbeta-mediated Akt phosphorylation at Ser473 residue expressed in PTEN-deficient human PC3 cells by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78G88PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi Research& Development

Curated by ChEMBL
LigandPNGBDBM50389073(CHEMBL2064340)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of human PI3Kbeta-mediated Akt phosphorylation at Ser473 residue expressed in PTEN-deficient human PC3 cells by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78G88PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi Research& Development

Curated by ChEMBL
LigandPNGBDBM50389066(CHEMBL2064347)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of human PI3Kbeta-mediated Akt phosphorylation at Ser473 residue expressed in PTEN-deficient human PC3 cells by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78G88PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi Research& Development

Curated by ChEMBL
LigandPNGBDBM50389062(CHEMBL2064352)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of human PI3Kbeta-mediated Akt phosphorylation at Ser473 residue expressed in PTEN-deficient human PC3 cells by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78G88PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi Research& Development

Curated by ChEMBL
LigandPNGBDBM50389047(CHEMBL2064328)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of N-terminus poly-His tagged human PI3Kbeta expressed in baculovirus infected insect S21 cells coexpressing p85alpha using PI(4,5)P2 as s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78G88PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi Research& Development

Curated by ChEMBL
LigandPNGBDBM50389072(CHEMBL2064341)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of N-terminus poly-His tagged human PI3Kbeta expressed in baculovirus infected insect S21 cells coexpressing p85alpha using PI(4,5)P2 as s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78G88PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi Research& Development

Curated by ChEMBL
LigandPNGBDBM50365890(CHEMBL1957875)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of N-terminus poly-His tagged human PI3Kbeta expressed in baculovirus infected insect S21 cells coexpressing p85alpha using PI(4,5)P2 as s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78G88PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi Research& Development

Curated by ChEMBL
LigandPNGBDBM50389042(CHEMBL2064331)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of N-terminus poly-His tagged human PI3Kbeta expressed in baculovirus infected insect S21 cells coexpressing p85alpha using PI(4,5)P2 as s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78G88PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi Research& Development

Curated by ChEMBL
LigandPNGBDBM50389046(CHEMBL2064327)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of N-terminus poly-His tagged human PI3Kbeta expressed in baculovirus infected insect S21 cells coexpressing p85alpha using PI(4,5)P2 as s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78G88PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Sanofi Research& Development

Curated by ChEMBL
LigandPNGBDBM50389069(CHEMBL2064344)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of poly-His tagged human PI3Kdelta expressed in baculovirus infected insect sf9 cells coexpressing p85alpha using PI(4,5)P2 as substrate p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78G88PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Sanofi Research& Development

Curated by ChEMBL
LigandPNGBDBM50389072(CHEMBL2064341)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of poly-His tagged human PI3Kdelta expressed in baculovirus infected insect sf9 cells coexpressing p85alpha using PI(4,5)P2 as substrate p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78G88PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi Research& Development

Curated by ChEMBL
LigandPNGBDBM50389042(CHEMBL2064331)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of human PI3Kbeta-mediated Akt phosphorylation at Ser473 residue expressed in PTEN-deficient human PC3 cells by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78G88PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi Research& Development

Curated by ChEMBL
LigandPNGBDBM50389035(CHEMBL2064419)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Inhibition of N-terminus poly-His tagged human PI3Kbeta expressed in baculovirus infected insect S21 cells coexpressing p85alpha using PI(4,5)P2 as s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78G88PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi Research& Development

Curated by ChEMBL
LigandPNGBDBM50389050(CHEMBL2064415)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Inhibition of human PI3Kbeta-mediated Akt phosphorylation at Ser473 residue expressed in PTEN-deficient human PC3 cells by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78G88PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi Research& Development

Curated by ChEMBL
LigandPNGBDBM50389062(CHEMBL2064352)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:Inhibition of N-terminus poly-His tagged human PI3Kbeta expressed in baculovirus infected insect S21 cells coexpressing p85alpha using PI(4,5)P2 as s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78G88PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi Research& Development

Curated by ChEMBL
LigandPNGBDBM50389052(CHEMBL2064413)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:Inhibition of N-terminus poly-His tagged human PI3Kbeta expressed in baculovirus infected insect S21 cells coexpressing p85alpha using PI(4,5)P2 as s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78G88PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi Research& Development

Curated by ChEMBL
LigandPNGBDBM50389049(CHEMBL2064416)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Inhibition of human PI3Kbeta-mediated Akt phosphorylation at Ser473 residue expressed in PTEN-deficient human PC3 cells by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78G88PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi Research& Development

Curated by ChEMBL
LigandPNGBDBM50389061(CHEMBL2064353)copy SMILEScopy InChI
Affinity DataIC50: 49nMAssay Description:Inhibition of human PI3Kbeta-mediated Akt phosphorylation at Ser473 residue expressed in PTEN-deficient human PC3 cells by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78G88PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi Research& Development

Curated by ChEMBL
LigandPNGBDBM50389066(CHEMBL2064347)copy SMILEScopy InChI
Affinity DataIC50: 57nMAssay Description:Inhibition of N-terminus poly-His tagged human PI3Kbeta expressed in baculovirus infected insect S21 cells coexpressing p85alpha using PI(4,5)P2 as s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78G88PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi Research& Development

Curated by ChEMBL
LigandPNGBDBM50389065(CHEMBL2064348)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of N-terminus poly-His tagged human PI3Kbeta expressed in baculovirus infected insect S21 cells coexpressing p85alpha using PI(4,5)P2 as s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78G88PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi Research& Development

Curated by ChEMBL
LigandPNGBDBM50389044(CHEMBL2064418)copy SMILEScopy InChI
Affinity DataIC50: 62nMAssay Description:Inhibition of human PI3Kbeta-mediated Akt phosphorylation at Ser473 residue expressed in PTEN-deficient human PC3 cells by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78G88PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi Research& Development

Curated by ChEMBL
LigandPNGBDBM50389076(CHEMBL2064336)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Inhibition of human PI3Kbeta-mediated Akt phosphorylation at Ser473 residue expressed in PTEN-deficient human PC3 cells by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78G88PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi Research& Development

Curated by ChEMBL
LigandPNGBDBM50389067(CHEMBL2064346)copy SMILEScopy InChI
Affinity DataIC50: 65nMAssay Description:Inhibition of human PI3Kbeta-mediated Akt phosphorylation at Ser473 residue expressed in PTEN-deficient human PC3 cells by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78G88PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi Research& Development

Curated by ChEMBL
LigandPNGBDBM50389073(CHEMBL2064340)copy SMILEScopy InChI
Affinity DataIC50: 72nMAssay Description:Inhibition of N-terminus poly-His tagged human PI3Kbeta expressed in baculovirus infected insect S21 cells coexpressing p85alpha using PI(4,5)P2 as s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78G88PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi Research& Development

Curated by ChEMBL
LigandPNGBDBM50389046(CHEMBL2064327)copy SMILEScopy InChI
Affinity DataIC50: 72nMAssay Description:Inhibition of human PI3Kbeta-mediated Akt phosphorylation at Ser473 residue expressed in PTEN-deficient human PC3 cells by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78G88PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi Research& Development

Curated by ChEMBL
LigandPNGBDBM50389038(CHEMBL2064406)copy SMILEScopy InChI
Affinity DataIC50: 75nMAssay Description:Inhibition of human PI3Kbeta-mediated Akt phosphorylation at Ser473 residue expressed in PTEN-deficient human PC3 cells by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78G88PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi Research& Development

Curated by ChEMBL
LigandPNGBDBM50389069(CHEMBL2064344)copy SMILEScopy InChI
Affinity DataIC50: 75nMAssay Description:Inhibition of N-terminus poly-His tagged human PI3Kbeta expressed in baculovirus infected insect S21 cells coexpressing p85alpha using PI(4,5)P2 as s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78G88PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi Research& Development

Curated by ChEMBL
LigandPNGBDBM50389043(CHEMBL2064330)copy SMILEScopy InChI
Affinity DataIC50: 76nMAssay Description:Inhibition of human PI3Kbeta-mediated Akt phosphorylation at Ser473 residue expressed in PTEN-deficient human PC3 cells by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78G88PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi Research& Development

Curated by ChEMBL
LigandPNGBDBM50389044(CHEMBL2064418)copy SMILEScopy InChI
Affinity DataIC50: 82nMAssay Description:Inhibition of N-terminus poly-His tagged human PI3Kbeta expressed in baculovirus infected insect S21 cells coexpressing p85alpha using PI(4,5)P2 as s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78G88PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi Research& Development

Curated by ChEMBL
LigandPNGBDBM50389041(CHEMBL2064333)copy SMILEScopy InChI
Affinity DataIC50: 82nMAssay Description:Inhibition of N-terminus poly-His tagged human PI3Kbeta expressed in baculovirus infected insect S21 cells coexpressing p85alpha using PI(4,5)P2 as s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78G88PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Sanofi Research& Development

Curated by ChEMBL
LigandPNGBDBM50389068(CHEMBL2064345)copy SMILEScopy InChI
Affinity DataIC50: 84nMAssay Description:Inhibition of poly-His tagged human PI3Kdelta expressed in baculovirus infected insect sf9 cells coexpressing p85alpha using PI(4,5)P2 as substrate p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78G88PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi Research& Development

Curated by ChEMBL
LigandPNGBDBM50389077(CHEMBL2064335)copy SMILEScopy InChI
Affinity DataIC50: 85nMAssay Description:Inhibition of human PI3Kbeta-mediated Akt phosphorylation at Ser473 residue expressed in PTEN-deficient human PC3 cells by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78G88PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi Research& Development

Curated by ChEMBL
LigandPNGBDBM50389043(CHEMBL2064330)copy SMILEScopy InChI
Affinity DataIC50: 86nMAssay Description:Inhibition of human PI3Kbeta-mediated Akt phosphorylation at Ser473 residue expressed in mouse MEF-3T3 cells after 0.5 to 2 hrs by Western blot analy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78G88PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi Research& Development

Curated by ChEMBL
LigandPNGBDBM50389060(CHEMBL2064354)copy SMILEScopy InChI
Affinity DataIC50: 88nMAssay Description:Inhibition of human PI3Kbeta-mediated Akt phosphorylation at Ser473 residue expressed in PTEN-deficient human PC3 cells by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78G88PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi Research& Development

Curated by ChEMBL
LigandPNGBDBM50389053(CHEMBL2064412)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Inhibition of N-terminus poly-His tagged human PI3Kbeta expressed in baculovirus infected insect S21 cells coexpressing p85alpha using PI(4,5)P2 as s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78G88PubMed
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