Compile Data Set for Download or QSAR
Found 27 Enz. Inhib. hit(s) with all data for entry = 50040147
TargetAdenosine receptor A2a(Homo sapiens (Human))
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)copy SMILEScopy InChI
Affinity DataKi:  200nMAssay Description:Displacement of [3H]ZM241385 from human AA2AR expressed in HEK293T cells after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58NFZPubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50389831(CHEMBL2070727)copy SMILEScopy InChI
Affinity DataKi:  631nMAssay Description:Displacement of [3H]ZM241385 from human AA2AR expressed in HEK293T cells after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58NFZPubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50389841(CHEMBL2070717)copy SMILEScopy InChI
Affinity DataKi:  631nMAssay Description:Displacement of [3H]ZM241385 from human AA2AR expressed in HEK293T cells after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58NFZPubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50389828(CHEMBL2070834)copy SMILEScopy InChI
Affinity DataKi:  794nMAssay Description:Displacement of [3H]dihydroalprenolol from human ADRB2 expressed in HEK293T cells after 1 hr by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58NFZPubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50389839(CHEMBL2070719)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nMAssay Description:Displacement of [3H]ZM241385 from human AA2AR expressed in HEK293T cells after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58NFZPubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM44650(1-({6-[(cyanomethyl)thio]benzimidazo[1,2-c]quinazo...)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nMAssay Description:Displacement of [3H]ZM241385 from human AA2AR expressed in HEK293T cells after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58NFZPubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM51080(4-[(2Z)-2-(2-oxo-1-naphthalenylidene)hydrazinyl]-1...)copy SMILEScopy InChI
Affinity DataKi:  1.26E+3nMAssay Description:Displacement of [3H]ZM241385 from human AA2AR expressed in HEK293T cells after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58NFZPubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50389846(CHEMBL2070720)copy SMILEScopy InChI
Affinity DataKi:  1.59E+3nMAssay Description:Displacement of [3H]ZM241385 from human AA2AR expressed in HEK293T cells after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58NFZPubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50389837(CHEMBL2070721)copy SMILEScopy InChI
Affinity DataKi:  1.59E+3nMAssay Description:Displacement of [3H]ZM241385 from human AA2AR expressed in HEK293T cells after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58NFZPubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50389827(CHEMBL1907082)copy SMILEScopy InChI
Affinity DataKi:  2.00E+3nMAssay Description:Displacement of [3H]dihydroalprenolol from human ADRB2 expressed in HEK293T cells after 1 hr by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58NFZPubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50389834(CHEMBL2070725)copy SMILEScopy InChI
Affinity DataKi:  2.51E+3nMAssay Description:Displacement of [3H]ZM241385 from human AA2AR expressed in HEK293T cells after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58NFZPubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50389832(CHEMBL2070726)copy SMILEScopy InChI
Affinity DataKi:  2.51E+3nMAssay Description:Displacement of [3H]ZM241385 from human AA2AR expressed in HEK293T cells after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58NFZPubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50389845(CHEMBL1362986)copy SMILEScopy InChI
Affinity DataKi:  3.98E+3nMAssay Description:Displacement of [3H]ZM241385 from human AA2AR expressed in HEK293T cells after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58NFZPubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50389835(CHEMBL2070724)copy SMILEScopy InChI
Affinity DataKi:  3.98E+3nMAssay Description:Displacement of [3H]ZM241385 from human AA2AR expressed in HEK293T cells after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58NFZPubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50389833(CHEMBL1089322)copy SMILEScopy InChI
Affinity DataKi:  5.01E+3nMAssay Description:Displacement of [3H]ZM241385 from human AA2AR expressed in HEK293T cells after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58NFZPubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50389844(CHEMBL2070728)copy SMILEScopy InChI
Affinity DataKi:  5.01E+3nMAssay Description:Displacement of [3H]ZM241385 from human AA2AR expressed in HEK293T cells after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58NFZPubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50389830(CHEMBL1714515)copy SMILEScopy InChI
Affinity DataKi:  5.01E+3nMAssay Description:Displacement of [3H]ZM241385 from human AA2AR expressed in HEK293T cells after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58NFZPubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50389836(CHEMBL2070722)copy SMILEScopy InChI
Affinity DataKi:  5.01E+3nMAssay Description:Displacement of [3H]ZM241385 from human AA2AR expressed in HEK293T cells after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58NFZPubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50389829(CHEMBL2070833)copy SMILEScopy InChI
Affinity DataKi:  5.01E+3nMAssay Description:Displacement of [3H]ZM241385 from human AA2AR expressed in HEK293T cells after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58NFZPubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50389842(CHEMBL2070723)copy SMILEScopy InChI
Affinity DataKi:  6.31E+3nMAssay Description:Displacement of [3H]ZM241385 from human AA2AR expressed in HEK293T cells after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58NFZPubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50389824(CHEMBL2070835)copy SMILEScopy InChI
Affinity DataKi:  2.51E+4nMAssay Description:Displacement of [3H]dihydroalprenolol from human ADRB2 expressed in HEK293T cells after 1 hr by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58NFZPubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50389826(CHEMBL1620339)copy SMILEScopy InChI
Affinity DataKi:  3.98E+4nMAssay Description:Displacement of [3H]dihydroalprenolol from human ADRB2 expressed in HEK293T cells after 1 hr by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58NFZPubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50389843(CHEMBL1622248)copy SMILEScopy InChI
Affinity DataKi:  3.98E+4nMAssay Description:Displacement of [3H]dihydroalprenolol from human ADRB2 expressed in HEK293T cells after 1 hr by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58NFZPubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50389825(CHEMBL1626178)copy SMILEScopy InChI
Affinity DataKi:  7.94E+5nMAssay Description:Displacement of [3H]dihydroalprenolol from human ADRB2 expressed in HEK293T cells after 1 hr by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58NFZPubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50420173(CHEMBL582739 | GNF-Pf-590)copy SMILEScopy InChI
Affinity DataEC50:  5.01E+4nMAssay Description:Induction of beta-arrestin2 recruitment to human S1PR1 expressed in CHOK1 cells after 2 hrs by beta-galactosidase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58NFZPubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50420172(CHEMBL2070836)copy SMILEScopy InChI
Affinity DataEC50:  2.00E+4nMAssay Description:Induction of beta-arrestin2 recruitment to human S1PR1 expressed in CHOK1 cells after 2 hrs by beta-galactosidase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58NFZPubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50420174(CHEMBL2070837)copy SMILEScopy InChI
Affinity DataEC50:  3.16E+4nMAssay Description:Induction of beta-arrestin2 recruitment to human S1PR1 expressed in CHOK1 cells after 2 hrs by beta-galactosidase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58NFZPubMed