Compile Data Set for Download or QSAR
Found 25 Enz. Inhib. hit(s) with all data for entry = 50040213
TargetSolute carrier family 22 member 8(Homo sapiens (Human))
Kyorin University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50206509(4-Dipropylsulfamoyl-benzoic acid | 4-Dipropylsulfa...)copy SMILEScopy InChI
Affinity DataIC50: 4.93E+3nMAssay Description:TP_TRANSPORTER: inhibition of ES uptake (ES: 50nM) in hOAT3-expressing S2 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0915PubMedDrugBank
TargetSolute carrier family 22 member 8(Rattus norvegicus)
Kyorin University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50206509(4-Dipropylsulfamoyl-benzoic acid | 4-Dipropylsulfa...)copy SMILEScopy InChI
Affinity DataIC50: 6.03E+3nMAssay Description:TP_TRANSPORTER: inhibition of ES uptake (ES: 50nM) in rOAT3-expressing S2 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0915PubMed
TargetSolute carrier family 22 member 8(Homo sapiens (Human))
Kyorin University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50344964(Betamipron | CHEMBL1231530 | N-(phenylcarbonyl)-be...)copy SMILEScopy InChI
Affinity DataIC50: 9.92E+3nMAssay Description:TP_TRANSPORTER: inhibition of ES uptake (ES: 50nM) in hOAT3-expressing S2 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0915PubMed
TargetSolute carrier family 22 member 6(Homo sapiens (Human))
Kyorin University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50206509(4-Dipropylsulfamoyl-benzoic acid | 4-Dipropylsulfa...)copy SMILEScopy InChI
Affinity DataIC50: 1.23E+4nMAssay Description:TP_TRANSPORTER: inhibition of PHA uptake (PHA: 5uM) in hOAT1-expressing S2 cellsMore data for this Ligand-Target Pair
TargetSolute carrier family 22 member 8(Homo sapiens (Human))
Kyorin University School of Medicine

Curated by ChEMBL
LigandPNGBDBM20688((3R,5R)-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-...)copy SMILEScopy InChI
Affinity DataIC50: 1.37E+4nMAssay Description:TP_TRANSPORTER: inhibition of ES uptake (ES: 50nM) in hOAT3-expressing S2 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0915PubMedDrugBank
TargetSolute carrier family 22 member 8(Rattus norvegicus)
Kyorin University School of Medicine

Curated by ChEMBL
LigandPNGBDBM20688((3R,5R)-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-...)copy SMILEScopy InChI
Affinity DataIC50: 1.56E+4nMAssay Description:TP_TRANSPORTER: inhibition of ES uptake (ES: 50nM) in rOAT3-expressing S2 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0915PubMed
TargetSolute carrier family 22 member 11(Homo sapiens (Human))
Kyorin University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50206509(4-Dipropylsulfamoyl-benzoic acid | 4-Dipropylsulfa...)copy SMILEScopy InChI
Affinity DataIC50: 2.54E+4nMAssay Description:TP_TRANSPORTER: inhibition of ES uptake (ES: 50nM) in hOAT4-expressing S2 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0915PubMedDrugBank
TargetSolute carrier family 22 member 6(Homo sapiens (Human))
Kyorin University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50344964(Betamipron | CHEMBL1231530 | N-(phenylcarbonyl)-be...)copy SMILEScopy InChI
Affinity DataIC50: 3.90E+4nMAssay Description:TP_TRANSPORTER: inhibition of PHA uptake (PHA: 5uM) in hOAT1-expressing S2 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0915PubMed
TargetSolute carrier family 22 member 8(Rattus norvegicus)
Kyorin University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50344964(Betamipron | CHEMBL1231530 | N-(phenylcarbonyl)-be...)copy SMILEScopy InChI
Affinity DataIC50: 4.75E+4nMAssay Description:TP_TRANSPORTER: inhibition of ES uptake (ES: 50nM) in rOAT3-expressing S2 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0915PubMed
TargetSolute carrier family 22 member 8(Homo sapiens (Human))
Kyorin University School of Medicine

Curated by ChEMBL
LigandPNGBDBM22889((Cimetidine) N-Methyl-N''''-[2-(5-methyl-1H-imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 9.24E+4nMAssay Description:TP_TRANSPORTER: inhibition of ES uptake (ES: 50nM) in hOAT3-expressing S2 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0915PubMed
TargetSolute carrier family 22 member 8(Rattus norvegicus)
Kyorin University School of Medicine

Curated by ChEMBL
LigandPNGBDBM22889((Cimetidine) N-Methyl-N''''-[2-(5-methyl-1H-imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 1.66E+5nMAssay Description:TP_TRANSPORTER: inhibition of ES uptake (ES: 50nM) in rOAT3-expressing S2 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0915PubMed
TargetSolute carrier family 22 member 8(Homo sapiens (Human))
Kyorin University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50367502(CILASTATIN)copy SMILEScopy InChI
Affinity DataIC50: 2.49E+5nMAssay Description:TP_TRANSPORTER: inhibition of ES uptake (ES: 50nM) in hOAT3-expressing S2 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0915PubMedDrugBank
TargetSolute carrier family 22 member 7(Homo sapiens (Human))
Kyorin University School of Medicine

Curated by ChEMBL
LigandPNGBDBM20688((3R,5R)-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-...)copy SMILEScopy InChI
Affinity DataIC50: 3.52E+5nMAssay Description:TP_TRANSPORTER: inhibition of PGF2alpha uptake (PGF2: 50nM) in hOAT2-expressing S2 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0915PubMedDrugBank
TargetSolute carrier family 22 member 6(Homo sapiens (Human))
Kyorin University School of Medicine

Curated by ChEMBL
LigandPNGBDBM20688((3R,5R)-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-...)copy SMILEScopy InChI
Affinity DataIC50: 4.08E+5nMAssay Description:TP_TRANSPORTER: inhibition of PHA uptake (PHA: 5uM) in hOAT1-expressing S2 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0915PubMedDrugBank
TargetSolute carrier family 22 member 7(Rattus norvegicus)
Kyorin University School of Medicine

Curated by ChEMBL
LigandPNGBDBM20688((3R,5R)-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-...)copy SMILEScopy InChI
Affinity DataIC50: 4.49E+5nMAssay Description:TP_TRANSPORTER: inhibition of PGF2alpha uptake (PGF2: 50nM) in rOAT2-expressing S2 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0915PubMed
TargetSolute carrier family 22 member 11(Homo sapiens (Human))
Kyorin University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50344964(Betamipron | CHEMBL1231530 | N-(phenylcarbonyl)-be...)copy SMILEScopy InChI
Affinity DataIC50: 4.83E+5nMAssay Description:TP_TRANSPORTER: inhibition of ES uptake (ES: 50nM) in hOAT4-expressing S2 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0915PubMed
TargetSolute carrier family 22 member 6(Homo sapiens (Human))
Kyorin University School of Medicine

Curated by ChEMBL
LigandPNGBDBM22889((Cimetidine) N-Methyl-N''''-[2-(5-methyl-1H-imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 4.92E+5nMAssay Description:TP_TRANSPORTER: inhibition of PHA uptake (PHA: 5uM) in hOAT1-expressing S2 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0915PubMed
TargetSolute carrier family 22 member 11(Homo sapiens (Human))
Kyorin University School of Medicine

Curated by ChEMBL
LigandPNGBDBM20688((3R,5R)-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-...)copy SMILEScopy InChI
Affinity DataIC50: 5.91E+5nMAssay Description:TP_TRANSPORTER: inhibition of ES uptake (ES: 50nM) in hOAT4-expressing S2 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0915PubMedDrugBank
TargetSolute carrier family 22 member 7(Homo sapiens (Human))
Kyorin University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50206509(4-Dipropylsulfamoyl-benzoic acid | 4-Dipropylsulfa...)copy SMILEScopy InChI
Affinity DataIC50: 6.68E+5nMAssay Description:TP_TRANSPORTER: inhibition of PGF2alpha uptake (PGF2: 50nM) in hOAT2-expressing S2 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0915PubMedDrugBank
TargetSolute carrier family 22 member 8(Rattus norvegicus)
Kyorin University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50367502(CILASTATIN)copy SMILEScopy InChI
Affinity DataIC50: 7.42E+5nMAssay Description:TP_TRANSPORTER: inhibition of ES uptake (ES: 50nM) in rOAT3-expressing S2 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0915PubMed
TargetSolute carrier family 22 member 7(Rattus norvegicus)
Kyorin University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50206509(4-Dipropylsulfamoyl-benzoic acid | 4-Dipropylsulfa...)copy SMILEScopy InChI
Affinity DataIC50: 9.77E+5nMAssay Description:TP_TRANSPORTER: inhibition of PGF2alpha uptake (PGF2: 50nM) in rOAT2-expressing S2 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0915PubMed
TargetSolute carrier family 22 member 6(Rattus norvegicus)
Kyorin University School of Medicine

Curated by ChEMBL
LigandPNGBDBM22889((Cimetidine) N-Methyl-N''''-[2-(5-methyl-1H-imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+6nMAssay Description:TP_TRANSPORTER: inhibition of PHA uptake (PHA: 5uM) in rOAT1-expressing S2 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0915PubMed
TargetSolute carrier family 22 member 11(Homo sapiens (Human))
Kyorin University School of Medicine

Curated by ChEMBL
LigandPNGBDBM22889((Cimetidine) N-Methyl-N''''-[2-(5-methyl-1H-imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+6nMAssay Description:TP_TRANSPORTER: inhibition of ES uptake (ES: 50nM) in hOAT4-expressing S2 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0915PubMed
TargetSolute carrier family 22 member 6(Rattus norvegicus)
Kyorin University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50367502(CILASTATIN)copy SMILEScopy InChI
Affinity DataIC50: 2.39E+6nMAssay Description:TP_TRANSPORTER: inhibition of PHA uptake (PHA: 5uM) in rOAT1-expressing S2 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0915PubMed
TargetSolute carrier family 22 member 6(Homo sapiens (Human))
Kyorin University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50367502(CILASTATIN)copy SMILEScopy InChI
Affinity DataIC50: 2.55E+6nMAssay Description:TP_TRANSPORTER: inhibition of PHA uptake (PHA: 5uM) in hOAT1-expressing S2 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0915PubMedDrugBank