Compile Data Set for Download or QSAR
Found 18 Enz. Inhib. hit(s) with all data for entry = 50040273
LigandPNGBDBM104963(CHEMBL507361 | US11147816, PD0325901 | US11701360,...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
LigandPNGBDBM50391802((3,4-difluoro-2-(2-fluoro-4-iodophenylamino)phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
LigandPNGBDBM50391804(CHEMBL2146893)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5P80PubMed
LigandPNGBDBM50391805(CHEMBL2146894)copy SMILEScopy InChI
Affinity DataIC50: 4.80nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5P80PubMed
LigandPNGBDBM50391811(CHEMBL2146895)copy SMILEScopy InChI
Affinity DataIC50: 5.10nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5P80PubMed
LigandPNGBDBM50391800(CHEMBL2146898)copy SMILEScopy InChI
Affinity DataIC50: 5.20nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5P80PubMed
LigandPNGBDBM50391803(CHEMBL2146888)copy SMILEScopy InChI
Affinity DataIC50: 6.60nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
LigandPNGBDBM50391801(CHEMBL2146892)copy SMILEScopy InChI
Affinity DataIC50: 7.20nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5P80PubMed
LigandPNGBDBM50391808(CHEMBL2146896)copy SMILEScopy InChI
Affinity DataIC50: 7.60nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5P80PubMed
LigandPNGBDBM50391806(CHEMBL2146899)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5P80PubMed
LigandPNGBDBM50391812(CHEMBL2146885)copy SMILEScopy InChI
Affinity DataIC50: 19.5nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5P80PubMed
LigandPNGBDBM50391797(CHEMBL2146890)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5P80PubMed
LigandPNGBDBM50391809(CHEMBL2146887)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
LigandPNGBDBM50391807(CHEMBL2146889)copy SMILEScopy InChI
Affinity DataIC50: 82nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5P80PubMed
LigandPNGBDBM50391798(CHEMBL2146891)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5P80PubMed
LigandPNGBDBM50391813(CHEMBL2146886)copy SMILEScopy InChI
Affinity DataIC50: 535nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5P80PubMed
LigandPNGBDBM50391810(CHEMBL2146884)copy SMILEScopy InChI
Affinity DataIC50: 801nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5P80PubMed
LigandPNGBDBM50391799(CHEMBL2146897)copy SMILEScopy InChI
Affinity DataIC50: 1.71E+3nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5P80PubMed