Compile Data Set for Download or QSAR
Found 44 Enz. Inhib. hit(s) with all data for entry = 50040282
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391864(CHEMBL2147287)copy SMILEScopy InChI
Affinity DataIC50: 0nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as unbound drug level causing inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391863(CHEMBL2147286)copy SMILEScopy InChI
Affinity DataIC50: 0.00100nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as unbound drug level causing inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391858(CHEMBL2147281)copy SMILEScopy InChI
Affinity DataIC50: 0.00100nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as unbound drug level causing inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391867(CHEMBL2147290)copy SMILEScopy InChI
Affinity DataIC50: 0.00200nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as unbound drug level causing inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391860(CHEMBL2147283)copy SMILEScopy InChI
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as unbound drug level causing inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50204367(CHEMBL410414 | dirlotapide)copy SMILEScopy InChI
Affinity DataIC50: 0.0110nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as unbound drug level causing inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391875(CHEMBL2147296)copy SMILEScopy InChI
Affinity DataIC50: 0.0210nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as unbound drug level causing inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391876(CHEMBL2147292)copy SMILEScopy InChI
Affinity DataIC50: 0.0250nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as unbound drug level causing inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391866(CHEMBL2147294)copy SMILEScopy InChI
Affinity DataIC50: 0.0580nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as unbound drug level causing inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391877(CHEMBL2147293)copy SMILEScopy InChI
Affinity DataIC50: 0.0660nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as unbound drug level causing inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391869(CHEMBL2147301)copy SMILEScopy InChI
Affinity DataIC50: 0.101nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as unbound drug level causing inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391871(CHEMBL2147298)copy SMILEScopy InChI
Affinity DataIC50: 0.105nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as unbound drug level causing inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391872(CHEMBL2147299)copy SMILEScopy InChI
Affinity DataIC50: 0.122nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as unbound drug level causing inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391874(CHEMBL2147295)copy SMILEScopy InChI
Affinity DataIC50: 0.253nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as unbound drug level causing inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391857(CHEMBL2147280)copy SMILEScopy InChI
Affinity DataIC50: 0.345nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as unbound drug level causing inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391856(CHEMBL2147279)copy SMILEScopy InChI
Affinity DataIC50: 0.378nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as unbound drug level causing inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391862(CHEMBL2147285)copy SMILEScopy InChI
Affinity DataIC50: 0.440nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391870(CHEMBL2147300)copy SMILEScopy InChI
Affinity DataIC50: 0.484nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as unbound drug level causing inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391861(CHEMBL2147284)copy SMILEScopy InChI
Affinity DataIC50: 0.550nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391875(CHEMBL2147296)copy SMILEScopy InChI
Affinity DataIC50: 0.560nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391863(CHEMBL2147286)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391869(CHEMBL2147301)copy SMILEScopy InChI
Affinity DataIC50: 0.630nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391858(CHEMBL2147281)copy SMILEScopy InChI
Affinity DataIC50: 0.740nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391867(CHEMBL2147290)copy SMILEScopy InChI
Affinity DataIC50: 0.770nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391865(CHEMBL2147291)copy SMILEScopy InChI
Affinity DataIC50: 0.830nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391876(CHEMBL2147292)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391873(CHEMBL2147297)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391873(CHEMBL2147297)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391868(CHEMBL2146489)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391864(CHEMBL2147287)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391868(CHEMBL2146489)copy SMILEScopy InChI
Affinity DataIC50: 1.21nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391857(CHEMBL2147280)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391856(CHEMBL2147279)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391860(CHEMBL2147283)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50204367(CHEMBL410414 | dirlotapide)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391878(CHEMBL2147289)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391859(CHEMBL2147282)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391879(CHEMBL2147288)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391866(CHEMBL2147294)copy SMILEScopy InChI
Affinity DataIC50: 4.30nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391877(CHEMBL2147293)copy SMILEScopy InChI
Affinity DataIC50: 7.5nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391872(CHEMBL2147299)copy SMILEScopy InChI
Affinity DataIC50: 9.40nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391871(CHEMBL2147298)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391874(CHEMBL2147295)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391870(CHEMBL2147300)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed