Compile Data Set for Download or QSAR
Found 40 Enz. Inhib. hit(s) with all data for entry = 50040597
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM20880((2S,3R,4R,5S,6R)-2-{4-chloro-3-[(4-ethoxyphenyl)me...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of sodium-dependent [14C]methyl-alpha-D-glucopyranoside uptake after 45 minsMore data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50303243((1S,3'R,4'S,5'S,6'R)-5-chloro-6-(4-ethylbenzyl)-6'...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of sodium-dependent [14C]methyl-alpha-D-glucopyranoside uptake after 45 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J9KPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50396767(CHEMBL2172387)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of sodium-dependent [14C]methyl-alpha-D-glucopyranoside uptake after 45 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J9KPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50396768(CHEMBL2172386)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of sodium-dependent [14C]methyl-alpha-D-glucopyranoside uptake after 45 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J9KPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50396776(CHEMBL2172494)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of sodium-dependent [14C]methyl-alpha-D-glucopyranoside uptake after 45 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J9KPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50396779(TOFOGLIFLOZIN)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of sodium-dependent [14C]methyl-alpha-D-glucopyranoside uptake after 45 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J9KPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50396777(CHEMBL2172493)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of sodium-dependent [14C]methyl-alpha-D-glucopyranoside uptake after 45 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J9KPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50396769(CHEMBL2172385)copy SMILEScopy InChI
Affinity DataIC50: 3.60nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of sodium-dependent [14C]methyl-alpha-D-glucopyranoside uptake after 45 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J9KPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50396780(CHEMBL2172491)copy SMILEScopy InChI
Affinity DataIC50: 4.80nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of sodium-dependent [14C]methyl-alpha-D-glucopyranoside uptake after 45 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J9KPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50396778(CHEMBL2172492)copy SMILEScopy InChI
Affinity DataIC50: 7.5nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of sodium-dependent [14C]methyl-alpha-D-glucopyranoside uptake after 45 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J9KPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50396781(CHEMBL2172389)copy SMILEScopy InChI
Affinity DataIC50: 9.10nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of sodium-dependent [14C]methyl-alpha-D-glucopyranoside uptake after 45 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J9KPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50303241((1S,3'R,4'S,5'S,6'R)-6-(4-ethoxybenzyl)-6'-(hydrox...)copy SMILEScopy InChI
Affinity DataIC50: 9.60nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of sodium-dependent [14C]methyl-alpha-D-glucopyranoside uptake after 45 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J9KPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50396771(CHEMBL2172383)copy SMILEScopy InChI
Affinity DataIC50: 14.2nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of sodium-dependent [14C]methyl-alpha-D-glucopyranoside uptake after 45 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J9KPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50396770(CHEMBL2172384)copy SMILEScopy InChI
Affinity DataIC50: 14.5nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of sodium-dependent [14C]methyl-alpha-D-glucopyranoside uptake after 45 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J9KPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM20875(1-(2,4-dihydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihyd...)copy SMILEScopy InChI
Affinity DataIC50: 16.4nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of sodium-dependent [14C]methyl-alpha-D-glucopyranoside uptake after 45 minsMore data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50396773(CHEMBL2172381)copy SMILEScopy InChI
Affinity DataIC50: 16.8nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of sodium-dependent [14C]methyl-alpha-D-glucopyranoside uptake after 45 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J9KPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50396775(CHEMBL2172379)copy SMILEScopy InChI
Affinity DataIC50: 29.9nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of sodium-dependent [14C]methyl-alpha-D-glucopyranoside uptake after 45 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J9KPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50396772(CHEMBL2172382)copy SMILEScopy InChI
Affinity DataIC50: 118nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of sodium-dependent [14C]methyl-alpha-D-glucopyranoside uptake after 45 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J9KPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50396774(CHEMBL2172380)copy SMILEScopy InChI
Affinity DataIC50: 123nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of sodium-dependent [14C]methyl-alpha-D-glucopyranoside uptake after 45 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J9KPubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50396768(CHEMBL2172386)copy SMILEScopy InChI
Affinity DataIC50: 126nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of sodium-dependent [14C]methyl-alpha-D-glucopyranoside uptake after 45 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J9KPubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50303243((1S,3'R,4'S,5'S,6'R)-5-chloro-6-(4-ethylbenzyl)-6'...)copy SMILEScopy InChI
Affinity DataIC50: 158nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of sodium-dependent [14C]methyl-alpha-D-glucopyranoside uptake after 45 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J9KPubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM20875(1-(2,4-dihydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihyd...)copy SMILEScopy InChI
Affinity DataIC50: 185nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of sodium-dependent [14C]methyl-alpha-D-glucopyranoside uptake after 45 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J9KPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50396766(CHEMBL2172388)copy SMILEScopy InChI
Affinity DataIC50: 241nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of sodium-dependent [14C]methyl-alpha-D-glucopyranoside uptake after 45 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J9KPubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50396767(CHEMBL2172387)copy SMILEScopy InChI
Affinity DataIC50: 388nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of sodium-dependent [14C]methyl-alpha-D-glucopyranoside uptake after 45 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J9KPubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM20880((2S,3R,4R,5S,6R)-2-{4-chloro-3-[(4-ethoxyphenyl)me...)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of sodium-dependent [14C]methyl-alpha-D-glucopyranoside uptake after 45 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J9KPubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50396780(CHEMBL2172491)copy SMILEScopy InChI
Affinity DataIC50: 3.09E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of sodium-dependent [14C]methyl-alpha-D-glucopyranoside uptake after 45 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J9KPubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50396775(CHEMBL2172379)copy SMILEScopy InChI
Affinity DataIC50: 4.99E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of sodium-dependent [14C]methyl-alpha-D-glucopyranoside uptake after 45 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J9KPubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50396766(CHEMBL2172388)copy SMILEScopy InChI
Affinity DataIC50: 5.13E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of sodium-dependent [14C]methyl-alpha-D-glucopyranoside uptake after 45 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J9KPubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50396776(CHEMBL2172494)copy SMILEScopy InChI
Affinity DataIC50: 5.31E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of sodium-dependent [14C]methyl-alpha-D-glucopyranoside uptake after 45 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J9KPubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50396769(CHEMBL2172385)copy SMILEScopy InChI
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of sodium-dependent [14C]methyl-alpha-D-glucopyranoside uptake after 45 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J9KPubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50396773(CHEMBL2172381)copy SMILEScopy InChI
Affinity DataIC50: 6.28E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of sodium-dependent [14C]methyl-alpha-D-glucopyranoside uptake after 45 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J9KPubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50396779(TOFOGLIFLOZIN)copy SMILEScopy InChI
Affinity DataIC50: 8.44E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of sodium-dependent [14C]methyl-alpha-D-glucopyranoside uptake after 45 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J9KPubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50396781(CHEMBL2172389)copy SMILEScopy InChI
Affinity DataIC50: 8.48E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of sodium-dependent [14C]methyl-alpha-D-glucopyranoside uptake after 45 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J9KPubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50396777(CHEMBL2172493)copy SMILEScopy InChI
Affinity DataIC50: 1.23E+4nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of sodium-dependent [14C]methyl-alpha-D-glucopyranoside uptake after 45 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J9KPubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50396778(CHEMBL2172492)copy SMILEScopy InChI
Affinity DataIC50: 1.31E+4nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of sodium-dependent [14C]methyl-alpha-D-glucopyranoside uptake after 45 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J9KPubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50396774(CHEMBL2172380)copy SMILEScopy InChI
Affinity DataIC50: 1.87E+4nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of sodium-dependent [14C]methyl-alpha-D-glucopyranoside uptake after 45 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J9KPubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50303241((1S,3'R,4'S,5'S,6'R)-6-(4-ethoxybenzyl)-6'-(hydrox...)copy SMILEScopy InChI
Affinity DataIC50: 1.87E+4nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of sodium-dependent [14C]methyl-alpha-D-glucopyranoside uptake after 45 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J9KPubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50396771(CHEMBL2172383)copy SMILEScopy InChI
Affinity DataIC50: 2.41E+4nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of sodium-dependent [14C]methyl-alpha-D-glucopyranoside uptake after 45 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J9KPubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50396770(CHEMBL2172384)copy SMILEScopy InChI
Affinity DataIC50: 2.89E+4nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of sodium-dependent [14C]methyl-alpha-D-glucopyranoside uptake after 45 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J9KPubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50396772(CHEMBL2172382)copy SMILEScopy InChI
Affinity DataIC50: 8.15E+4nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of sodium-dependent [14C]methyl-alpha-D-glucopyranoside uptake after 45 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J9KPubMed