Compile Data Set for Download or QSAR
Found 46 Enz. Inhib. hit(s) with all data for entry = 50040754
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50331095(CHEMBL1289494 | Tivozanib | US10464902, Tivozanib)copy SMILEScopy InChI
Affinity DataIC50: 0.160nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP03XZPubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50331095(CHEMBL1289494 | Tivozanib | US10464902, Tivozanib)copy SMILEScopy InChI
Affinity DataIC50: 0.210nMAssay Description:Inhibition of VEGFR1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP03XZPubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50331095(CHEMBL1289494 | Tivozanib | US10464902, Tivozanib)copy SMILEScopy InChI
Affinity DataIC50: 0.240nMAssay Description:Inhibition of VEGFR3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP03XZPubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50399540(FORETINIB | US10464902, Foretinib | US10882853, Co...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of METMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50399540(FORETINIB | US10464902, Foretinib | US10882853, Co...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Inhibition of VEGFR1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP03XZPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50399537(CHEMBL2180604)copy SMILEScopy InChI
Affinity DataIC50: 0.950nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP03XZPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50331096(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-6-methoxy-7...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP03XZPubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50399537(CHEMBL2180604)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of VEGFR3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP03XZPubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
University of Genoa

Curated by ChEMBL
LigandPNGBDBM24773(AMG 706 | AMG-706 | Motesanib | N-(3,3-dimethyl-1,...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of VEGFR1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP03XZPubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50399540(FORETINIB | US10464902, Foretinib | US10882853, Co...)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:Inhibition of VEGFR3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP03XZPubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50331096(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-6-methoxy-7...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of VEGFR3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP03XZPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University of Genoa

Curated by ChEMBL
LigandPNGBDBM24773(AMG 706 | AMG-706 | Motesanib | N-(3,3-dimethyl-1,...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50399537(CHEMBL2180604)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of VEGFR1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP03XZPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50331094(4-(3-chloro-4-(3-cyclopropylureido)phenoxy)-7-meth...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50399538(BAY-579352 | CHEMBL2079588)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of VEGFR3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP03XZPubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50399535(CHEMBL2180602)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of RETMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP03XZPubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50399535(CHEMBL2180602)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of c-KitMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP03XZPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50399535(CHEMBL2180602)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of FLT3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP03XZPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50399535(CHEMBL2180602)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP03XZPubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50331096(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-6-methoxy-7...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of VEGFR1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP03XZPubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50331094(4-(3-chloro-4-(3-cyclopropylureido)phenoxy)-7-meth...)copy SMILEScopy InChI
Affinity DataIC50: 5.20nMAssay Description:Inhibition of VEGFR3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP03XZPubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
University of Genoa

Curated by ChEMBL
LigandPNGBDBM24773(AMG 706 | AMG-706 | Motesanib | N-(3,3-dimethyl-1,...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of VEGFR3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP03XZPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University of Genoa

Curated by ChEMBL
LigandPNGBDBM25115(3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-({[4-(py...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of VEGFR2 by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP03XZPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50399538(BAY-579352 | CHEMBL2079588)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP03XZPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50399540(FORETINIB | US10464902, Foretinib | US10882853, Co...)copy SMILEScopy InChI
Affinity DataIC50: 6.80nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP03XZPubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50399539(CHEMBL2180605)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of VEGFR1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP03XZPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50356877(CHEMBL1614710)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP03XZPubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50356877(CHEMBL1614710)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of c-KitMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP03XZPubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50399539(CHEMBL2180605)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of VEGFR3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP03XZPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University of Genoa

Curated by ChEMBL
LigandPNGBDBM25115(3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-({[4-(py...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP03XZPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50399540(FORETINIB | US10464902, Foretinib | US10882853, Co...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of VEGFR2 phosphorylation in HUVECMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP03XZPubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50399539(CHEMBL2180605)copy SMILEScopy InChI
Affinity DataIC50: 17.5nMAssay Description:Inhibition of FGFR1More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50356877(CHEMBL1614710)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP03XZPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50399539(CHEMBL2180605)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP03XZPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50399536(CHEMBL2180603)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP03XZPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50356877(CHEMBL1614710)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of c-RafMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP03XZPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University of Genoa

Curated by ChEMBL
LigandPNGBDBM4851((4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-...)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP03XZPubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
University of Genoa

Curated by ChEMBL
LigandPNGBDBM26105(6-{4-[(4-ethylpiperazin-1-yl)methyl]phenyl}-N-[(1R...)copy SMILEScopy InChI
Affinity DataIC50: 59nMAssay Description:Inhibition of VEGFR1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP03XZPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50141809(2-(2-{4-[4-(4-tert-Butyl-phenylamino)-phenoxy]-6-m...)copy SMILEScopy InChI
Affinity DataIC50: 69nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP03XZPubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50141809(2-(2-{4-[4-(4-tert-Butyl-phenylamino)-phenoxy]-6-m...)copy SMILEScopy InChI
Affinity DataIC50: 69nMAssay Description:Inhibition of PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP03XZPubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50141809(2-(2-{4-[4-(4-tert-Butyl-phenylamino)-phenoxy]-6-m...)copy SMILEScopy InChI
Affinity DataIC50: 69nMAssay Description:Inhibition of c-KitMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP03XZPubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50141809(2-(2-{4-[4-(4-tert-Butyl-phenylamino)-phenoxy]-6-m...)copy SMILEScopy InChI
Affinity DataIC50: 69nMAssay Description:Inhibition of FGFR2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP03XZPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University of Genoa

Curated by ChEMBL
LigandPNGBDBM26105(6-{4-[(4-ethylpiperazin-1-yl)methyl]phenyl}-N-[(1R...)copy SMILEScopy InChI
Affinity DataIC50: 77nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP03XZPubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50399539(CHEMBL2180605)copy SMILEScopy InChI
Affinity DataIC50: 82.5nMAssay Description:Inhibition of FGFR2More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
University of Genoa

Curated by ChEMBL
LigandPNGBDBM4851((4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of VEGFR1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP03XZPubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
University of Genoa

Curated by ChEMBL
LigandPNGBDBM4851((4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-...)copy SMILEScopy InChI
Affinity DataIC50: 195nMAssay Description:Inhibition of VEGFR3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP03XZPubMed