Found 19 Enz. Inhib. hit(s) with all data for entry = 50041757 
Affinity DataIC50: 316nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
Affinity DataIC50: 316nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 5.01E+4nMAssay Description:Displacement of dofetilide from human ERGMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 5.01E+4nMAssay Description:Displacement of dofetilide from human ERGMore data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 31.6nMAssay Description:Agonist activity at human TGR5 expressed in melanophores assessed as melanosome dispersion by melanophore assayMore data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Rattus norvegicus)
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 2.00E+3nMAssay Description:Agonist activity at rat TGR5 expressed in melanophores assessed as melanosome dispersion by melanophore assayMore data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 79.4nMAssay Description:Agonist activity at human TGR5 expressed in melanophores assessed as melanosome dispersion by melanophore assayMore data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 501nMAssay Description:Agonist activity at TGR5 expressed in human U2-OS cells assessed as increase in MRE/CRE-driven gene expression by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 5.01E+3nMAssay Description:Agonist activity at TGR5 expressed in human U2-OS cells assessed as increase in MRE/CRE-driven gene expression by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Rattus norvegicus)
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 631nMAssay Description:Agonist activity at rat TGR5 expressed in melanophores assessed as melanosome dispersion by melanophore assayMore data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 158nMAssay Description:Agonist activity at TGR5 expressed in human U2-OS cells assessed as increase in MRE/CRE-driven gene expression by luciferase reporter gene assayMore data for this Ligand-Target Pair
