Compile Data Set for Download or QSAR
Found 41 Enz. Inhib. hit(s) with all data for entry = 50041957
TargetHistamine H3 receptor(Homo sapiens (Human))
VU University Amsterdam

Curated by ChEMBL
LigandPNGBDBM22542(4-(1H-imidazol-4-ylmethyl)piperidine | 4-(1H-imida...)copy SMILEScopy InChI
Affinity DataKi:  0.501nMAssay Description:Displacement of [3H]histamine from human H3 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2JDXPubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
VU University Amsterdam

Curated by ChEMBL
LigandPNGBDBM22916(5-{3-[(4-iodophenyl)methoxy]propyl}-1H-imidazole |...)copy SMILEScopy InChI
Affinity DataKi:  0.631nMAssay Description:Displacement of [3H]histamine from human H3 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2JDXPubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
VU University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50419448(CHEMBL1923026)copy SMILEScopy InChI
Affinity DataKi:  1.02nMAssay Description:Displacement of [3H]histamine from human H3 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2JDXPubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
VU University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50419444(CHEMBL43934 | VUF-5228)copy SMILEScopy InChI
Affinity DataKi:  1.05nMAssay Description:Displacement of [3H]histamine from human H3 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2JDXPubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
VU University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50419456(CHEMBL1923034)copy SMILEScopy InChI
Affinity DataKi:  1.15nMAssay Description:Displacement of [3H]histamine from human H3 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2JDXPubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
VU University Amsterdam

Curated by ChEMBL
LigandPNGBDBM22911(2-(3H-imidazol-4-yl)ethylsulfanylmethanimidamide |...)copy SMILEScopy InChI
Affinity DataKi:  1.58nMAssay Description:Displacement of [3H]histamine from human H3 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2JDXPubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
VU University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50419455(CHEMBL1923033)copy SMILEScopy InChI
Affinity DataKi:  1.62nMAssay Description:Displacement of [3H]histamine from human H3 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2JDXPubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
VU University Amsterdam

Curated by ChEMBL
LigandPNGBDBM22541(Clobenpropit | N''-[(4-chlorophenyl)methyl]{[3-(1H...)copy SMILEScopy InChI
Affinity DataKi:  2.82nMAssay Description:Displacement of [3H]histamine from human H3 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2JDXPubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
VU University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50419454(CHEMBL1923032)copy SMILEScopy InChI
Affinity DataKi:  4.68nMAssay Description:Displacement of [3H]histamine from human H3 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2JDXPubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
VU University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50419449(CHEMBL1923027)copy SMILEScopy InChI
Affinity DataKi:  4.90nMAssay Description:Displacement of [3H]histamine from human H3 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2JDXPubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
VU University Amsterdam

Curated by ChEMBL
LigandPNGBDBM7966(2-(1H-imidazol-4-yl)ethan-1-amine | CHEMBL544208 |...)copy SMILEScopy InChI
Affinity DataKi:  6.31nMAssay Description:Displacement of [3H]histamine from human H3 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2JDXPubMedDrugBank
TargetHistamine H4 receptor(Homo sapiens (Human))
VU University Amsterdam

Curated by ChEMBL
LigandPNGBDBM22911(2-(3H-imidazol-4-yl)ethylsulfanylmethanimidamide |...)copy SMILEScopy InChI
Affinity DataKi:  6.31nMAssay Description:Displacement of [3H]histamine from human H4 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
VU University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50419446(CHEMBL1923024)copy SMILEScopy InChI
Affinity DataKi:  9.77nMAssay Description:Displacement of [3H]histamine from human H3 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2JDXPubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
VU University Amsterdam

Curated by ChEMBL
LigandPNGBDBM22541(Clobenpropit | N''-[(4-chlorophenyl)methyl]{[3-(1H...)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:Displacement of [3H]histamine from human H4 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2JDXPubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
VU University Amsterdam

Curated by ChEMBL
LigandPNGBDBM22916(5-{3-[(4-iodophenyl)methoxy]propyl}-1H-imidazole |...)copy SMILEScopy InChI
Affinity DataKi:  12.6nMAssay Description:Displacement of [3H]histamine from human H4 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2JDXPubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
VU University Amsterdam

Curated by ChEMBL
LigandPNGBDBM22566(5-chloro-2-[(4-methylpiperazin-1-yl)carbonyl]-1H-i...)copy SMILEScopy InChI
Affinity DataKi:  15.8nMAssay Description:Displacement of [3H]histamine from human H4 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2JDXPubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
VU University Amsterdam

Curated by ChEMBL
LigandPNGBDBM7966(2-(1H-imidazol-4-yl)ethan-1-amine | CHEMBL544208 |...)copy SMILEScopy InChI
Affinity DataKi:  15.8nMAssay Description:Displacement of [3H]histamine from human H4 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2JDXPubMedDrugBank
TargetHistamine H4 receptor(Homo sapiens (Human))
VU University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50419447(CHEMBL1923025)copy SMILEScopy InChI
Affinity DataKi:  16.2nMAssay Description:Displacement of [3H]histamine from human H4 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2JDXPubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
VU University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50419450(CHEMBL1923028)copy SMILEScopy InChI
Affinity DataKi:  17.0nMAssay Description:Displacement of [3H]histamine from human H3 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2JDXPubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
VU University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50419452(CHEMBL1923030)copy SMILEScopy InChI
Affinity DataKi:  18.6nMAssay Description:Displacement of [3H]histamine from human H3 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2JDXPubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
VU University Amsterdam

Curated by ChEMBL
LigandPNGBDBM22542(4-(1H-imidazol-4-ylmethyl)piperidine | 4-(1H-imida...)copy SMILEScopy InChI
Affinity DataKi:  19.9nMAssay Description:Displacement of [3H]histamine from human H4 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2JDXPubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
VU University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50419453(CHEMBL1923031)copy SMILEScopy InChI
Affinity DataKi:  29.5nMAssay Description:Displacement of [3H]histamine from human H4 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2JDXPubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
VU University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50419443(CHEMBL1196470)copy SMILEScopy InChI
Affinity DataKi:  31.6nMAssay Description:Displacement of [3H]histamine from human H4 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2JDXPubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
VU University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50419452(CHEMBL1923030)copy SMILEScopy InChI
Affinity DataKi:  31.6nMAssay Description:Displacement of [3H]histamine from human H4 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2JDXPubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
VU University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50419451(CHEMBL1923029)copy SMILEScopy InChI
Affinity DataKi:  32.4nMAssay Description:Displacement of [3H]histamine from human H3 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2JDXPubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
VU University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50419445(CHEMBL1923023)copy SMILEScopy InChI
Affinity DataKi:  42.7nMAssay Description:Displacement of [3H]histamine from human H3 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2JDXPubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
VU University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50419445(CHEMBL1923023)copy SMILEScopy InChI
Affinity DataKi:  42.7nMAssay Description:Displacement of [3H]histamine from human H4 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2JDXPubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
VU University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50419447(CHEMBL1923025)copy SMILEScopy InChI
Affinity DataKi:  46.8nMAssay Description:Displacement of [3H]histamine from human H3 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2JDXPubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
VU University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50419444(CHEMBL43934 | VUF-5228)copy SMILEScopy InChI
Affinity DataKi:  47.9nMAssay Description:Displacement of [3H]histamine from human H4 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2JDXPubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
VU University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50419453(CHEMBL1923031)copy SMILEScopy InChI
Affinity DataKi:  67.6nMAssay Description:Displacement of [3H]histamine from human H3 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2JDXPubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
VU University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50419446(CHEMBL1923024)copy SMILEScopy InChI
Affinity DataKi:  75.9nMAssay Description:Displacement of [3H]histamine from human H4 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2JDXPubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
VU University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50419454(CHEMBL1923032)copy SMILEScopy InChI
Affinity DataKi:  89.1nMAssay Description:Displacement of [3H]histamine from human H4 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2JDXPubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
VU University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50419449(CHEMBL1923027)copy SMILEScopy InChI
Affinity DataKi:  89.1nMAssay Description:Displacement of [3H]histamine from human H4 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2JDXPubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
VU University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50419455(CHEMBL1923033)copy SMILEScopy InChI
Affinity DataKi:  126nMAssay Description:Displacement of [3H]histamine from human H4 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2JDXPubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
VU University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50419456(CHEMBL1923034)copy SMILEScopy InChI
Affinity DataKi:  135nMAssay Description:Displacement of [3H]histamine from human H4 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2JDXPubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
VU University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50419448(CHEMBL1923026)copy SMILEScopy InChI
Affinity DataKi:  148nMAssay Description:Displacement of [3H]histamine from human H4 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2JDXPubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
VU University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50001884(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)copy SMILEScopy InChI
Affinity DataKi:  200nMAssay Description:Displacement of [3H]histamine from human H4 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2JDXPubMedDrugBank
TargetHistamine H4 receptor(Homo sapiens (Human))
VU University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50419450(CHEMBL1923028)copy SMILEScopy InChI
Affinity DataKi:  229nMAssay Description:Displacement of [3H]histamine from human H4 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2JDXPubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
VU University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50419443(CHEMBL1196470)copy SMILEScopy InChI
Affinity DataKi:  316nMAssay Description:Displacement of [3H]histamine from human H3 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2JDXPubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
VU University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50419451(CHEMBL1923029)copy SMILEScopy InChI
Affinity DataKi:  380nMAssay Description:Displacement of [3H]histamine from human H4 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2JDXPubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
VU University Amsterdam

Curated by ChEMBL
LigandPNGBDBM22566(5-chloro-2-[(4-methylpiperazin-1-yl)carbonyl]-1H-i...)copy SMILEScopy InChI
Affinity DataKi:  5.01E+3nMAssay Description:Displacement of [3H]histamine from human H3 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2JDXPubMed